Opin vísindi: Síðast bætt við

  • Ostacolo, Kevin (University of Iceland, School of Health Sciences, Faculty of Medicine, 2023-11-16)
    ATG7, an essential protein for cellular homeostasis, plays a pivotal role in regulating autophagy. The autophagy process ensures the degradation and recycling of cellular components for proper cell function. ATG7 facilitates the lipidation of ATG8 ...
  • Klarenberg, Ingeborg J.; Keuschnig, Christoph; Russi Colmenares, Ana J.; Warshan, Denis; Jungblut, Anne D.; Jónsdóttir, Ingibjörg S.; Vilhelmsson, Oddur (Wiley, 2021-11)
    Bacterial communities form the basis of biogeochemical processes and determine plant growth and health. Mosses harbour diverse bacterial communities that are involved in nitrogen fixation and carbon cycling. Global climate change is causing changes in ...
  • TBnet (2023-10-01)
    BackgroundEuropean-specific policies for tuberculosis (TB) elimination require identification of key populations that benefit from TB screening.AimWe aimed to identify groups of foreign-born individuals residing in European countries that benefit most ...
  • Stacey, Simon N.; Zink, Florian; Halldórsson, Gísli Hreinn; Stefánsdóttir, Lilja; Guðjónsson, Sigurjón Axel; Einarsson, Gudmundur; Hjörleifsson, Grimur; Eiríksdóttir, Þjóðbjörg; Helgadottir, Anna; Björnsdottir, Gyda; Thorgeirsson, Thorgeir E.; Ólafsdóttir, Þórunn Ásta; Jónsdóttir, Ingileif; Gretarsdottir, Solveig; Tragante, Vinicius; Magnússon, Magnús Karl; Jonsson, Hakon; Gudmundsson, Julius; Olafsson, Sigurgeir; Holm, Hilma; Gudbjartsson, Daniel F.; Sulem, Patrick; Helgason, Agnar Sturla; Þorsteinsdóttir, Unnur; Tryggvadottir, Laufey; Rafnar, Thorunn; Melsted, Páll; Úlfarsson, Magnús Örn; Viðarsson, Brynjar; Thorleifsson, Gudmar; Stefánsson, Kári (2023-12)
    Clonal hematopoiesis (CH) arises when a substantial proportion of mature blood cells is derived from a single hematopoietic stem cell lineage. Using whole-genome sequencing of 45,510 Icelandic and 130,709 UK Biobank participants combined with a mutational ...
  • Jónasdóttir, Ásta Dögg; Manojlovic, Milena; Vojinovic, Jelena; Nordin, Annica; Bruchfeld, Annette; Gunnarsson, Iva; Mobarrez, Fariborz; Antovic, Aleksandra (2023-10-17)
    Objectives: To study circulating myeloperoxidase (MPO)-positive extracellular vesicles (MPO+EVs) exposing citrullinated histone-3 (H3Cit), tissue factor (TF), and plasminogen (Plg) in association to thrombin generation in patients with anti-neutrophil ...
  • Jónsdóttir, Helga; Halldórsdóttir, Bryndís Stefanía; Ingadóttir, Þorbjörg Sóley (2024-04)
    Aim: The increase in the number of people with chronic obstructive pulmonary disease (COPD) and the disease burden, has prompted concerted efforts to improve healthcare, particularly outpatient services. In line with these attempts the Partnership-Based ...
  • Rögnvaldsson, Kristján Godsk (University of Iceland, School of Health Sciences, Faculty of Medicine, 2023-11)
    Inngangur. Þrátt fyrir að næstum öld sé liðin frá uppgötvun penisillíns og að langt sé liðið síðan bólusetningar hófust gegn Streptococcus pneumoniae (pneumokokkum), algengasta orsakavaldi lungnabólgu fullorðinna, er enn um algengan og alvarlegan sjúkdóm ...
  • Eldjarn, Grimur Hjorleifsson; Ferkingstad, Egil; Lund, Sigrun H.; Helgason, Hannes; Magnusson, Olafur Th; Gunnarsdottir, Kristbjorg; Olafsdottir, Thorunn A.; Halldorsson, Bjarni V.; Olason, Pall I.; Zink, Florian; Gudjonsson, Sigurjon A.; Sveinbjornsson, Gardar; Magnusson, Magnus I.; Helgason, Agnar; Oddsson, Asmundur; Halldorsson, Gisli H.; Magnusson, Magnus K.; Sævarsdóttir, Sædís; Eiriksdottir, Thjodbjorg; Masson, Gisli; Stefansson, Hreinn; Jonsdottir, Ingileif; Holm, Hilma; Rafnar, Thorunn; Melsted, Pall; Saemundsdottir, Jona; Norddahl, Gudmundur L.; Thorleifsson, Gudmar; Ulfarsson, Magnus O.; Gudbjartsson, Daniel F.; Thorsteinsdottir, Unnur; Sulem, Patrick; Stefansson, Kari (2023-10-04)
    High-throughput proteomics platforms measuring thousands of proteins in plasma combined with genomic and phenotypic information have the power to bridge the gap between the genome and diseases. Here we performed association studies of Olink Explore ...
  • Koskinen, Sanna; Brugnolli, Anna; Fuster-Linares, Pilar; Hourican, Susan; Istomina, Natalja; Leino-Kilpi, Helena; Löyttyniemi, Eliisa; Nemcová, Jana; Meyer, Gabriele; De Oliveira, Célia Simão; Palese, Alvisa; Rua, Marília; Salminen, Leena; Sveinsdóttir, Herdís; Visiers-Jiménez, Laura; Zeleníková, Renáta; Kajander-Unkuri, Satu (2023-08-14)
    Background: Job satisfaction is a key factor for the successful transition of newly graduated nurses (NGNs) and for retaining NGNs in their workplaces. However, there is limited evidence of the relationship between satisfaction regarding the nursing ...
  • Boretti, Gabriele; Giordano, Emanuele; Ionita, Mariana; Vlasceanu, George Mihail; Sigurjónsson, Ólafur Eysteinn; Gargiulo, Paolo; Lovecchio, Joseph (2023-09-01)
    Tissue-engineered bone tissue grafts are a promising alternative to the more conventional use of natural donor bone grafts. However, choosing an appropriate biomaterial/scaffold to sustain cell survival, proliferation, and differentiation in a 3D ...
  • Erlingsdottir, Helga Ýr; Ketilsdóttir, Auður; Hendriks, Jeroen M.; Ingadóttir, Brynja (2023)
    Purpose: To evaluate the disease-related knowledge of outpatients with atrial fibrillation (AF), and the relationship with health literacy and other background variables. Patients and Methods: In this cross-sectional survey study, conducted in Iceland, ...
  • Xu, Shanshan; Marcon, Alessandro; Bertelsen, Randi Jacobsen; Benediktsdóttir, Bryndís; Brandt, Jørgen; Engemann, Kristine; Frohn, Lise Marie; Geels, Camilla; Gíslason, Þórarinn; Heinrich, Joachim; Holm, Mathias; Janson, Christer; Markevych, Iana; Modig, Lars; Orru, Hans; Schlünssen, Vivi; Sigsgaard, Torben; Johannessen, Ane (2023-11)
    Background: Air pollution has been linked to mortality, but there are few studies examining the association with different exposure time windows spanning across several decades. The evidence for the effects of green space and mortality is contradictory. ...
  • Goodman, Sarah Jessica; Luperchio, Teresa Romeo; Ellegood, Jacob; Chater-Diehl, Eric; Lerch, Jason P.; Björnsson, Hans Tómas; Weksberg, Rosanna (2023-12)
    Background: Recent findings from studies of mouse models of Mendelian disorders of epigenetic machinery strongly support the potential for postnatal therapies to improve neurobehavioral and cognitive deficits. As several of these therapies move into ...
  • Capone, Emily; Tryggvason, Þórður; Cela, Ilaria; Dufrusine, Beatrice; Pinti, Morena; Del Pizzo, Francesco; Gunnarsdóttir, Helga Sigrún; Grottola, Tommaso; De Laurenzi, Vincenzo; Iacobelli, Stefano; Lattanzio, Rossano; Sala, Gianluca (2023-10-28)
    HER-3 (also known as ErbB-3) is a human epidermal growth factor receptor tyrosine kinases family member, and its expression in CRC (colorectal cancer) tissues was previously associated with poor prognosis. In this study, HER-3 expression was analyzed ...
  • Sigurdarson, Sigurdur S.; Kristjánsson, Már; Björnsson, Einar Stefán (2024-03-01)
    Liver injury associated with the use of a number of different of herbal and dietary supplements are increasingly recognized. It is though often unclear which of the sometimes multiple ingredients are responsible for the liver injury. Several case reports ...
  • Bjornsdottir, Gyda; Chalmer, Mona A.; Stefánsdóttir, Lilja; Skuladottir, Astros Th; Einarsson, Gudmundur; Andrésdóttir, Margrét; Beyter, Doruk; Ferkingstad, Egil; Gretarsdottir, Solveig; Halldórsson, Bjarni Vilhjálmur; Halldórsson, Gísli Hreinn; Helgadottir, Anna; Helgason, Hannes; Hjorleifsson Eldjarn, Grimur; Jonasdottir, Adalbjorg; Jonasdottir, Aslaug; Jónsdóttir, Ingileif; Knowlton, Kirk U.; Nadauld, Lincoln D.; Lund, Sigrún Helga; Magnusson, Olafur Th; Melsted, Páll; Moore, Kristjan H.S.; Oddsson, Asmundur; Olason, Pall I.; Sigurdsson, Asgeir; Stefansson, Olafur A.; Saemundsdottir, Jona; Sveinbjornsson, Gardar; Tragante, Vinicius; Unnsteinsdottir, Unnur; Walters, Guðmundur Bragi; Zink, Florian; Rødevand, Linn; Andreassen, Ole A.; Igland, Jannicke; Lie, Rolv T.; Haavik, Jan; Banasik, Karina; Brunak, Søren; Didriksen, Maria; T. Bruun, Mie; Erikstrup, Christian; Kogelman, Lisette J.A.; Nielsen, Kaspar R.; Sørensen, Erik; Pedersen, Ole B.; Ullum, Henrik; Bay, Jakob; Boldsen, Jens K.; Brodersen, Thorsten; Burgdorf, Kristoffer; Dinh, Khoa M.; Dowsett, Joseph; Feenstra, Bjarke; Geller, Frank; Hindhede, Lotte; Hjalgrim, Henrik; Jacobsen, Rikke L.; Jemec, Gregor; Kaspersen, Katrine; Kjerulf, Bertram D.; Larsen, Margit A.H.; Louloudis, Ioannis; Lundgaard, Agnete; Mikkelsen, Susan; Mikkelsen, Christina; Nissen, Ioanna; Nyegaard, Mette; Henriksen, Alexander P.; Rohde, Palle D.; Rostgaard, Klaus; Swinn, Michael; Thørner, Lise W.; Bruun, Mie T.; Werge, Thomas; Westergaard, David; Masson, Gisli; Þorsteinsdóttir, Unnur; Olesen, Jes; Ludvigsson, Petur; Thorarensen, Ólafur; Bjornsdottir, Anna; Sigurdardottir, Gudrun R.; Sveinsson, Ólafur Árni; Ostrowski, Sisse R.; Holm, Hilma; Gudbjartsson, Daniel F.; Thorleifsson, Gudmar; Sulem, Patrick; Stefansson, Hreinn; Thorgeirsson, Thorgeir E.; Hansen, Thomas F.; Stefánsson, Kári (2023-11)
    Migraine is a complex neurovascular disease with a range of severity and symptoms, yet mostly studied as one phenotype in genome-wide association studies (GWAS). Here we combine large GWAS datasets from six European populations to study the main migraine ...
  • Forss, Mikko; Bolsunovskyi, Kostiantyn; Lee, Yung; Kilpeläinen, Tuomas P.; Aoki, Yoshitaka; Gudjonsson, Sigurdur; Hervé, François; Järvinen, Petrus; Malde, Sachin; Miyazawa, Katsuhito; Sairanen, Jukka; Sander, Lotte; Violette, Philippe D.; Witte, Lambertus P.W.; Guyatt, Gordon H.; Tikkinen, Kari A.O. (2023-12)
    Background: Although hydrocele is one of the most common urologic pathologies, it is seldom studied, and the major urologic associations have no guidelines for the management of adult hydroceles. Objective: To characterize international practice variation ...
  • Unnsteinsdóttir Kristensen, Ingunn (2022-12)
    Concussion symptoms are complex. They are non-specific to a concussion, and there is no gold standard for diagnosis and evaluation. For most, symptoms will resolve in days or weeks following a concussion. However, symptoms can become more serious, ...
  • Stensrud, Jens; Oskarsson, Oskar Orn; Erlendsdóttir, Helga; Thors, Valtýr Stefánsson (2023-11)
    Ellefu mánaða gömul stúlka var send á bráðamóttöku Barnaspítala Hringsins vegna hita og slappleika. Stúlkan var bráðveik við skoðun með sveiflukennda meðvitund. Henni versnaði mjög hratt stuttu eftir komu og reyndist hún vera með heilahimnubólgu af ...
  • Ólafsson, Ragnar Pétur; Kvaran, Karol; Ketilsdottir, Kristin; Hallgrimsdottir, Kolbrun; Sigurdsson, Emil L; Sigurðsson, Engilbert (2023-11)
    Ágrip INNGANGUR Áhugi á notkun hugvíkkandi efna, oft ofskynjunarefna, hefur aukist á undanförnum árum samhliða fréttum af mögulegum meðferðarávinningi þeirra. Ekkert er þó vitað um þekkingu og viðhorf heilbrigðisstarfsfólks til efnanna hér á landi. ...