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Browsing Doktorsritgerðir- HÍ by Department "Faculty of Medicine (UI)"
Now showing items 41-60 of 91
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(2021-04)A better understanding of normal organ development can give deeper insight into which genes are harnessed by aberrant cells during cancer formation and progression. In my thesis, I have investigated two seemingly different, however, related, developmental ... -
(University of Iceland, School of Health Sciences, Faculty of Medicine, 2022-12)Neurodevelopmental disorders on the impulsivity-compulsivity spectrum are chronic disabling conditions with an early onset. High rates of comorbidity have been reported between Tourette syndrome (TS), Tics disorder (Tics), obsessive compulsive ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2021-10-08)Kransæðasjúkdómur dregur fleiri til dauða á hverju ári en nokkur annar sjúkdómur á heimsvísu. Sjúkdómurinn einkennist af framvindu æðakölkunar, sem er flókið og margþætt ferli. Á undanförnum 14 árum hafa rannsóknir með víðtækri erfðamengisleit leitt ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2023-06)Introduction and aims: Development of the nervous system is a complex and highly regulated process that, when impaired, can result in a multitude of disorders of varying behavioural, cognitive, and functional severity. Variation in brain structure and ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2016-12)Background and aims: Previous studies in geothermal and volcanic areas have shown high risk of certain types of cancers. The aim was to study the association between residence in geothermal areas and the incidence and mortality of cancer in ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-08)The microenvironment is increasingly being recognized as a key player in supporting cancer progression. Therefore, investigating heterotypic interactions between cancer cells and their microenvironment is important for improving our understanding ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2021-06)Aims: The aims of this thesis were: (1) to describe functioning and contextual factors of community-dwelling stroke survivors 1-2 years after their first stroke, based on the International Classification of Functioning, Disability and Health (ICF) ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2021-06-15)Breast cancer is the most common type of cancer in women worldwide. It is also a highly heterogeneous disease that is characterized by an array of genetic rearrangements, including copy number alterations (CNA), translocations, inversions, ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2016-12)Psoriasis is a chronic immune-mediated inflammatory skin disease with a strong genetic background and profound effects on psychosocial wellbeing. Streptococcal throat infections are known to trigger or exacerbate psoriasis in some patients, and several ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2018-12)Pneumococci are commonly carried asymptomatically in the nasopharynx, especially in children. Pneumococci are also one of the major bacterial pathogens causing both severe infections and non-severe infections in both children and adults. The most severe ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2022-09)Introduction: Interstitial lung diseases (ILD), such as idiopathic pulmonary fibrosis (IPF), are diseases of elderly people that are characterised by pulmonary deposition of fibrous tissue and often have a poor prognosis. Interstitial lung abnormalities ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2021-09)Vitað er að mikil aukning hefur verið á grunnfrumu og flöguþekjumeinum í húð síðustu ár í vestrænum löndum en ekki er alveg skýrt hvers vegna svo er. Helstu áhættuþættir þessara meina eru ljós húð og útfjólublá geislun, og einnig hafa sum lyf verið ...
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Lífefni í mænuvökva nýbura: forspárgildi fyrir heilaskaða. Tengsl við lifun og röskun á taugaþroska (University of Iceland, School of Health Sciences, Faculty of Medicine, 2022-06)Bakgrunnur Ágrip Börn sem verða fyrir súrefnisskorti í fæðingu og börn sem fæðast fyrir fulla meðgöngu eiga á hættu að lifa ekki af eða hljóta varanlegan heilaskaða. Hættan á þessum fylgikvillum hefur ekki minnkað á síðustu áratugum þrátt fyrir miklar ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2023-01-06)Injuries involving major arteries and the thorax are major causes of mortality and morbidity worldwide. Studies on the epidemiology of vascular trauma are scarce and preventive measures are of utmost importance, such as improved roads and safer vehicles. ...
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(University of Iceland, School of Health Sciences, Faculty of Medcine, 2016-11)Background and aims: Macroeconomic fluctuations have shown various effects on population health, but the evidence base for their influence on maternal health and birth outcomes is scarce and inconclusive. The overall aim of this thesis was to examine ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2023-05-22)Background: Transdiagnostic mechanisms of change (txMOC) in cognitive behaviour therapy (CBT) are seldom studied. Despite this omission, transdiagnostic CBT (txCBT) is established as effective for common mental health problems such as anxiety and ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-04)Transcriptional regulatory mechanisms drive the maturation of B cells to plasma cells, with a dramatic transcriptional rewiring taking place during the transition. This rewiring is dependent on a number of factors, including the transcription factor B ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2026-09-16)Wiedemann-Steiner heilkenni (WDSTS) er sjaldgæfur erfðasjúkdómur sem veldur greindarskerðingu sem enn reynist ólæknandi og lítið er vitað um sjúkdómsmyndun þess. Orsakir WDSTS eru arfblendnar stökkbreytingar í geni sem táknar fyrir ensíminu ...
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Metabolic systems analysis of breast epithelial cells following epithelial-to-mesenchymal transition (University of Iceland, School of Health Sciences, Faculty of Medicine, 2022-02-25)Breast cancer is a heterogenous disease in which the mechanism for signalling, gene expression, metabolism and growth in breast tissue is deranged. Breast cancer is responsible for the death of over 600,000 people worldwide on a yearly basis. By ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2023-03-30)Breast cancer is the most frequently diagnosed cancer today, with approximately 2.3 million new cases for the year 2020. Regardless of gender, these diagnoses represent 11.7% of all cases. For women, breast cancer falls under roughly one-third of cancer ...
Now showing items 41-60 of 91