• 

  A homozygous loss-of-function mutation leading to CYBC1 deficiency causes chronic granulomatous disease 

  Arnadottir, Gudny; Norðdahl, Guðmundur L.; Gudmundsdottir, Steinunn; Ágústsdóttir, Arna B.; Sigurðsson, Snævar; Jensson, Brynjar O.; Bjarnadóttir, Kristbjörg; Theodórs, Fannar; Benonisdottir, Stefania; Ívarsdóttir, Erna V.; Oddsson, Asmundur; Kristjánsson, Ragnar P.; Sulem, Gerald; Alexandersson, Kristján F.; Júlíusdóttir, Þórhildur; Guðmundsson, Kjartan R.; Sæmundsdóttir, Jóna; Jónasdóttir, Aðalbjörg; Jónasdóttir, Áslaug; Sigurðsson, Ásgeir; Manzanillo, Paolo; Guðjónsson, Sigurjón Axel; Thorisson, Gudmundur A.; Magnússon, Ólafur Þ.; Másson, Gísli; Örvar, Kjartan B.; Holm, Hilma; Björnsson, Sigurður; Arngrimsson, Reynir; Gudbjartsson, Daniel; Thorsteinsdottir, Unnur; Jonsdottir, Ingileif; Haraldsson, Ásgeir; Sulem, Patrick; Stefansson, Kari (Springer Science and Business Media LLC, 2018-10-25)

  Mutations in genes encoding subunits of the phagocyte NADPH oxidase complex are recognized to cause chronic granulomatous disease (CGD), a severe primary immunodeficiency. Here we describe how deficiency of CYBC1, a previously uncharacterized protein ...
• 

  Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA 

  Gudmundsson, Julius; Sigurðsson, Jón K.; Stefánsdóttir, Lilja; Agnarsson, Bjarni A.; Ísaksson, Helgi J.; Stefánsson, Ólafur A.; Guðjónsson, Sigurjón Axel; Gudbjartsson, Daniel; Másson, Gísli; Frigge, Michael L.; Stacey, Simon N.; Sulem, Patrick; Halldorsson, Gisli H.; Tragante, Vinicius; Hólm, Hilma; Eyjólfsson, Guðmundur I.; Sigurðardóttir, Ólöf; Olafsson, Isleifur; Jónsson, Þorvaldur; Jónsson, Eirikur; Barkardóttir, Rósa B.; Hilmarsson, Rafn; Asselbergs, Folkert W.; Geirsson, Guðmundur; Thorsteinsdottir, Unnur; Rafnar, Thorunn; Thorleifsson, Gudmar; Stefansson, Kari (Springer Science and Business Media LLC, 2018-11-08)

  Benign prostatic hyperplasia and associated lower urinary tract symptoms (BPH/LUTS) are common conditions affecting the majority of elderly males. Here we report the results of a genome-wide association study of symptomatic BPH/LUTS in 20,621 patients ...
• 

  Genome-wide association meta-analysis yields 20 loci associated with gallstone disease 

  Ferkingstad, Egil; Oddsson, Asmundur; Gretarsdottir, Solveig; Benonisdottir, Stefania; Thorleifsson, Gudmar; Deaton, Aimee M.; Jónsson, Stefán; Stefánsson, Ólafur A.; Norðdahl, Guðmundur L.; Zink, Florian; Arnadottir, Gudny; Gunnarsson, Bjarni; Halldorsson, Gisli; Helgadottir, Anna; Jensson, Brynjar O.; Kristjánsson, Ragnar P.; Sveinbjörnsson, Garðar; Sverrisson, Davíð A.; Másson, Gísli; Olafsson, Isleifur; Eyjólfsson, Guðmundur I.; Sigurðardóttir, Ólöf; Hólm, Hilma; Jonsdottir, Ingileif; Ólafsson, Sigurður; Steingrimsdottir, Thora; Rafnar, Thorunn; Björnsson, Einar S.; Thorsteinsdottir, Unnur; Gudbjartsson, Daniel; Sulem, Patrick; Stefansson, Kari (Springer Science and Business Media LLC, 2018-11-30)

  Gallstones are responsible for one of the most common diseases in the Western world and are commonly treated with cholecystectomy. We perform a meta-analysis of two genomewide association studies of gallstone disease in Iceland and the UK, totaling ...
• 

  Biomechanical risk factors for ACL injury: Development of analysis methods specific to injury mechanism 

  Sigurðsson, Haraldur Björn (University of Iceland, School of Health Sciences, Faculty of Medicine, 2019)

  Aims: The aim of the doctoral project was to develop and assess data extraction and analysis methods specific to the anterior cruciate ligament injury mechanism. The aim of paper I was to evaluate differences in the timing of the peak knee valgus moment ...
• 

  Vegakerfið og ferðamálin 

  Valsson, Trausti (Vegagerðin, 2000)

  Ferðamálin hafa fylgt framþróuninni í samgöngumálum. Rakið er upphaf fastra ferða til Íslands og síðan áfangar í þróun samgangna á landi. Könnun á samgöngumöguleikum sýnir síðan ýmislegt um hvernig ferðaþjónustan muni þróast í framtíðinni. Bókin er ...
• 

  Land sem auðlind: um mótun byggðamynsturs á Suðvesturlandi í fortíð, nútíð, framtíð 

  Valsson, Trausti (Fjölvi, 1993)
• 

  Framtíðarsýn: Ísland á 21. öld 

  Valsson, Trausti (Fjölvi, 1991)
• 

  Reykjavík - vaxtarbroddur: þróun höfuðborgar 

  Valsson, Trausti (Fjölvi, 1986)
• 

  Hugmynd að fyrsta heildarskipulagi Íslands: byggt á könnun á helstu byggðaforsendum á Íslandi 

  Valsson, Trausti (1987)
• 

  Exploration of Planetary Hyperspectral Images with Unsupervised Spectral Unmixing: A Case Study of Planet Mars 

  Liu, Jun; Luo, Bin; Douté, Sylvain; Chanussot, Jocelyn (MDPI AG, 2018-05-10)

  We propose to replace traditional spectral index methods by unsupervised spectral unmixing methods for the exploration of large datasets of planetary hyperspectral images. The main goal of this article is to test the ability of these analysis techniques ...
• 

  Weed suppression greatly increased by plant diversity in intensively managed grasslands: A continental-scale experiment 

  Connolly, John; Sebastià, Maria-Teresa; Kirwan, Laura; Finn, John Anthony; Llurba, Rosa; Suter, Matthias; Collins, Rosemary P.; Porqueddu, Claudio; Helgadóttir, Áslaug; Baadshaug, Ole H.; Bélanger, Gilles; Black, Alistair; Brophy, Caroline; Čop, Jure; Dalmannsdottir, Sigridur; Delgado, Ignacio; Elgersma, Anjo; Fothergill, Michael; Frankow-Lindberg, Bodil E.; Ghesquiere, An; Golinski, Piotr; Grieu, Philippe; Gustavsson, Anne-Maj; Höglind, Mats; Huguenin-Elie, Olivier; Jørgensen, Marit; Kadziuliene, Zydre; Lunnan, Tor; Nykanen-Kurki, Paivi; Ribas, Angela; Taube, Friedhelm; Thumm, Ulrich; De Vliegher, Alex; Lüscher, Andreas (Wiley, 2017-09-27)

  Grassland diversity can support sustainable intensification of grassland production through increased yields, reduced inputs and limited weed invasion. We report the effects of diversity on weed suppression from 3 years of a 31-site continental-scale ...
• 

  Northern lights assay: a versatile method for comprehensive detection of DNA damage 

  Guðmundsson, Bjarki; Þormar, Hans G; Sigurðsson, Albert; Dankers, Wendy; Steinarsdóttir, Margrét; Hermanowicz, Stefan; Sigurðsson, Stefán; Ólafsson, Davið; Halldorsdottir, Anna; Meyn, Stephen; Jonsson, Jon J. (Oxford University Press (OUP), 2018-07-24)

  DNA damage assays have various limitations in types of lesions detected, sensitivity, specificity and samples that can be analyzed. The Northern Lights Assay (NLA) is based on 2D Strandness-Dependent Electrophoresis (2D-SDE), a technique that separates ...
• 

  Uniaxial and lateral strain behavior of ribbed reinforcement bars inspected with digital image correlation 

  Eiriksson, Haukur; Bessason, Bjarni; Unnthorsson, Runar (Wiley-Blackwell, 2018-05-30)

  Knowledge about the plastic behavior of reinforcement steel bars in reinforced concrete (RC) structures is important, especially for seismic design. This paper presents the results of experimental tests where the main aim was to map the plastic ...
• 

  Observation of bosonic condensation in a hybrid monolayer MoSe2-GaAs microcavity 

  Waldherr, Max; Lundt, Nils; Klaas, Martin; Betzold, Simon; Wurdack, Matthias; Baumann, Vasilij; Estrecho, Eliezer; Nalitov, Anton; Cherotchenko, Evgenia; Cai, Hui; Ostrovskaya, Elena A.; Kavokin, Alexey V.; Tongay, Sefaattin; Klembt, Sebastian; Höfling, Sven; Schneider, Christian (Springer Science and Business Media LLC, 2018-08-16)

  Bosonic condensation belongs to the most intriguing phenomena in physics, and was mostly reserved for experiments with ultra-cold quantum gases. More recently, it became accessible in exciton-based solid-state systems at elevated temperatures. Here, ...
• 

  Fish Intake in Pregnancy and Offspring Metabolic Parameters at Age 9–16—Does Gestational Diabetes Modify the Risk? 

  Maslova, Ekaterina; Hansen, Susanne; Strøm, Marin; Halldorsson, Thorhallur; Grunnet, Louise; Vaag, Allan; Olsen, Sjurdur (MDPI AG, 2018-10-17)

  Oily fish, an important source of marine n-3 long-chain polyunsaturated fatty acids (LCPUFA), has shown to reduce cardiometabolic risk in adults. Whether maternal fish intake affects offspring metabolic health is less established, especially among ...
• 

  The Troll Inside You: Paranormal Activity in the Medieval North 

  Jakobsson, Ármann (Punctum Books, 2017-07-18)
• 

  Sequence variants in the PTCH1 gene associate with spine bone mineral density and osteoporotic fractures 

  Styrkarsdottir, Unnur; Thorleifsson, Gudmar; Gudjonsson, Sigurjon A.; Sigurdsson, Asgeir; Center, Jacqueline R.; Lee, Seung Hun; Nguyen, Tuan V.; Kwok, Timothy C.Y.; Lee, Jenny S.W.; Ho, Suzanne C.; Woo, Jean; Leung, Ping-C.; Kim, Beom-Jun; Rafnar, Thorunn; Kiemeney, Lambertus A.; Ingvarsson, Thorvaldur; Koh, Jung-Min; Tang, Nelson L.S.; Eisman, John A.; Christiansen, Claus; Sigurdsson, Gunnar; Thorsteinsdottir, Unnur; Stefansson, Kari (Springer Science and Business Media LLC, 2016-01-06)

  Bone mineral density (BMD) is a measure of osteoporosis and is useful in evaluating the risk of fracture. In a genome-wide association study of BMD among 20,100 Icelanders, with follow-up in 10,091 subjects of European and East-Asian descent, we found ...
• 

  Demodex folliculorum, hársekkjamítill, vangreind orsök hvarmabólgu 

  Gunnarsdóttir, Sigurlaug; Kristmundsson, Árni; Freeman, Mark A.; Björnsson, Ólafur Már; Zoëga, Gunnar Már (Laeknabladid/The Icelandic Medical Journal, 2016-05-04)

  Vanstarfsemi í fitukirtlum augnloka er algeng ástæða augnþurrks. Demodex-mítlar geta valdið slíkri vanstarfsemi og þar með hvarmabólgu með kláða, þurrki og almennri vanlíðan á augnsvæði. Það er mikilvægt að hafa Demodex-mítla í huga við greiningu ...
• 

  Electronic Genealogy and Cancer Databases in Cancer Genetic Counselling 

  Stefánsdóttir, Vigdís (University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-09)

  The overall aim of this PhD thesis was to cohesively assess the availability and use of electronic genealogy databases and information from cancer registries to construct electronically generated pedigrees for risk assessment in genetic counselling. ...
• 

  Dietary intake is associated with risk of multiple myeloma and its precursor disease 

  Thordardottir, Marianna; Lindqvist, Ebba K.; Lund, Sigrún Helga; Costello, Rene; Burton, Debra; Steingrimsdottir, Laufey; Korde, Neha; Mailankody, Sham; Eiriksdottir, Gudny; Launer, Lenore J.; Gudnason, Vilmundur; Harris, Tamara B.; Landgren, Ola; Torfadottir, Johanna; Kristinsson, Sigurður Yngvi (Public Library of Science (PLoS), 2018-11-01)

  The etiology of monoclonal gammopathy of undetermined significance (MGUS), the precursor state of multiple myeloma (MM), is mostly unknown and no studies have been conducted on the effect of diet on MGUS or progression from MGUS to MM. We aimed to ...

View more