Opin vísindi

Fletta eftir deild "Læknadeild (HÍ)"

Fletta eftir deild "Læknadeild (HÍ)"

Röðun: Raða: Niðurstöður:

  • Maret-Ouda, John; Wahlin, Karl; Artama, Miia; Brusselaers, Nele; Färkkilä, Martti; Lynge, Elsebeth; Mattsson, Fredrik; Pukkala, Eero; Romundstad, Pål; Tryggvadottir, Laufey; Euler-Chelpin, My von; Lagergren, Jesper (BMJ, 2017-06)
    Purpose To describe a newly created all-Nordic cohort of patients with gastro-oesophageal reflux disease (GORD), entitled the Nordic Antireflux Surgery Cohort (NordASCo), which will be used to compare participants having undergone antireflux surgery ...
  • Yi, Zhiqian; Su, Yixi; Cherek, Paulina; Nelson, David R.; Lin, Jianping; Rolfsson, Óttar; Wu, Hua; Salehi-Ashtiani, Kourosh; Brynjolfsson, Sigurdur; Fu, Weiqi (Springer Science and Business Media LLC, 2019-12-02)
    Background: Diatoms, which can accumulate large amounts of carotenoids, are a major group of microalgae and the dominant primary producer in marine environments. Phaeodactylum tricornutum, a model diatom species, acquires little silicon for its growth ...
  • Handsaker, Joseph C.; Brown, Steven J.; Petrovic, Milos; Bowling, Frank L.; Rajbhandari, Satyan; Marple-Horvat, Dilwyn E; Boulton, Andrew J.M.; Reeves, Neil D. (Elsevier BV, 2019-10)
    Introduction: Patients with diabetes and diabetic peripheral neuropathy (DPN) place their feet with less accuracy whilst walking, which may contribute to the increased falls-risk. This study examines the effects of a multi-faceted intervention on ...
  • Hjálmarsdóttir, Martha Ásdís; Quirk, Sigríður Júlía; Haraldsson, Gunnsteinn; Erlendsdóttir, Helga; Haraldsson, Ásgeir; Kristinsson, Karl G. (Public Library of Science (PLoS), 2017-01-26)
    Background Information on pneumococcal serotype distribution before vaccination is a prerequisite for evaluation of vaccine effect. The aim was to investigate the prevalence of pneumococcal serotypes isolated from middle ear (ME), lower respiratory ...
  • Arnardóttir, Nanna Ýr; Óskarsdóttir, Nína Dóra; Brychta, Robert J.; Koster, Annemarie; van Domelen, Dane R.; Caserotti, Paolo; Eiriksdottir, Gudny; Sverrisdóttir, Jóhanna E.; Jóhannsson, Erlingur; Launer, Lenore J.; Gudnason, Vilmundur; Harris, Tamara B.; Chen, Kong Y.; Sveinsson, Thorarinn (MDPI AG, 2017-10-21)
    In Iceland, there is a large variation in daylight between summer and winter. The aim of the study was to identify how this large variation influences physical activity (PA) and sedentary behavior (SB). Free living PA was measured by a waist-worn ...
  • Haraldsdottir, Sigurdis; Rafnar, Thorunn; Frankel, Wendy L.; Einarsdóttir, Sylvía; Sigurðsson, Ásgeir; Hampel, Heather; Snaebjornsson, Petur; Másson, Gísli; Weng, Daniel; Arngrimsson, Reynir; Kehr, Birte; Yilmaz, Ahmet; Haraldsson, Stefan; sulem, patrick; Stefansson, Tryggvi; Shields, Peter G.; Sigurðsson, Fridbjörn; Bekaii-Saab, Tanios; Moller, Pall H.; Steinarsdóttir, Margrét; Alexíusdóttir, Kristín; Hitchins, Megan; Pritchard, Colin C.; de la Chapelle, Albert; Jónasson, Jón Gunnlaugur; Goldberg, Richard M.; Stefansson, Kari (Springer Nature, 2017-05-03)
    Lynch syndrome, caused by germline mutations in the mismatch repair genes, is associated with increased cancer risk. Here using a large whole-genome sequencing data bank, cancer registry and colorectal tumour bank we determine the prevalence of Lynch ...
  • Ingason, Arnar; Sigfússon, Gunnlaugur; Torfason, Bjarni (Springer Nature, 2018-06-07)
    Background Unicuspid unicommissural aortic valve is an extremely rare congenital anomaly that usually presents in adulthood but can rarely present in infancy. We report a 17-year-old patient with congenital aortic stenosis secondary to unicuspid ...
  • Jensson, Brynjar Örn; Hansdottir, Sif; Arnadottir, Gudny; Sulem, Gerald; Kristjansson, Ragnar; Oddsson, Asmundur; Benonisdottir, Stefania; Jónsson, Hákon; Helgason, Agnar; Sæmundsdóttir, Jóna; Magnússon, Ólafur T.; Másson, Gísli; Thorisson, Gudmundur; Jónasdóttir, Aðalbjörg; Jónasdóttir, Áslaug; Sigurðsson, Ásgeir; Jonsdottir, Ingileif; Pétursdóttir, Vigdís; Kristinsson, Jón R.; Gudbjartsson, Daniel; Thorsteinsdottir, Unnur; Arngrimsson, Reynir; sulem, patrick; Guðmundsson, Gunnar; Stefansson, Kari (Springer Nature, 2017-11-14)
    Background: Rare missense mutations in the gene encoding coatomer subunit alpha (COPA) have recently been shown to cause autoimmune interstitial lung, joint and kidney disease, also known as COPA syndrome, under a dominant mode of inheritance. Case ...
  • Sigurgeirsdottir, Jonina; Halldorsdottir, Sigridur; Arnardóttir, Ragnheiður Harpa; Gudmundsson, Gunnar; Björnsson, Eythor (Dove Medical Press Ltd., 2019-05-16)
    Background: COPD is a common cause of morbidity and mortality. The aim of this study was to explore patients’ experiences, self-reported needs, and needs-driven strategies to cope with self-management of COPD. Patients and methods: In this phenomenological ...
  • Frick, Elisabet; Gudjonsson, Thorkell; Eyfjörð, Jórunn Erla; Jonasson, Jon; Tryggvadóttir, Laufey; Stefansson, Olafur; Sigurdsson, Stefan (Impact Journals, LLC, 2019-07-23)
    Estrogen receptor-positive breast cancer is subdivided into subtypes LuminalA and LuminalB, based on different expression patterns. MicroRNA-190b has been reported to be up-regulated in estrogen receptor-positive breast cancers. In this study we aimed ...
  • Stefansson, Olafur; Hermanowicz, Stefan; van der Horst, Jasper; Hilmarsdóttir, Hólmfríður; Staszczak, Zuzanna; Jónasson, Jón Gunnlaugur; Tryggvadottir, Laufey; Guðjónsson, Þorkell; Sigurðsson, Stefán (Springer Nature, 2017-07-05)
    Background DNA repair of alkylation damage is defective in various cancers. This occurs through somatically acquired inactivation of the MGMT gene in various cancer types, including breast cancers. In addition to MGMT, the two E. coli AlkB homologs ...
  • Sigmarsdóttir, Þóra; McGarrity, Sarah; Rolfsson, Óttar; Yurkovich, James T.; Sigurjónsson, Ólafur E. (Frontiers Media SA, 2020-03-31)
    Mesenchymal stem cells are a promising source for externally grown tissue replacements and patient-specific immunomodulatory treatments. This promise has not yet been fulfilled in part due to production scaling issues and the need to maintain the correct ...
  • Káradóttir, Harpa; Nikhil Nitin, Kulkarn; Guðjónsson, Þórarinn; Karason, Sigurbergur; Guðmundsson, Guðmundur Hrafn (PeerJ, 2015-12-07)
    Mechanical ventilation (MV) of patients can cause damage to bronchoalveolar epithelium, leading to a sterile inflammatory response, infection and in severe cases sepsis. Limited knowledge is available on the effects of MV on the innate immune defense ...
  • Wang, Juan; Janson, Christer; Lindberg, Eva; Holm, Mathias; Gislason, Thorarinn; Benediktsdóttir, Bryndís; Johannessen, Ane; Schlünssen, Vivi; Jogi, Rain; Franklin, Karl A.; Norbäck, Dan (Elsevier BV, 2020-06)
    Aim: To investigate whether exposure to dampness and mold at home and at work induce sleep disturbances and daytime sleepiness among adults. Materials and methods: Associations between onset of sleep disturbances and dampness, mold and mold odor at ...
  • Einarsson, Einar Jón; Patel, Mitesh; Petersen, Hannes; Wiebe, Thomas; Fransson, Per-Anders; Magnusson, Måns; Moëll, Christian (Springer Nature, 2016-11-10)
    The objective of cancer treatment is to secure survival. However, as chemotherapeutic agents can affect the central and peripheral nervous systems, patients must undergo a process of central compensation. We explored the effectiveness of this compensation ...
  • Triebner, Kai; Johannessen, Ane; Svanes, Cecilie; Leynaert, Bénédicte; Benediktsdóttir, Bryndís; Demoly, Pascal; Dharmage, Shyamali C.; Franklin, Karl A.; Heinrich, Joachim; Holm, Mathias; Jarvis, Deborah; Lindberg, Eva; Rovira, Jesús Martínez Moratalla; Muniozguren Agirre, Nerea; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Skulstad, Svein Magne; Hustad, Steinar; Rodriguez, Francisco J.; Gómez Real, Francisco (Public Library of Science (PLoS), 2020-06-30)
    Objective: Most women live to experience menopause and will spend 4–8 years transitioning from fertile age to full menstrual stop. Biologically, reproductive ageing is a continuous process, but by convention, it is defined categorically as pre-, peri- ...
  • Ólafsdóttir, Steinunn A.; Jonsdottir, Helga; Magnusson, Charlotte; Caltenco, Héctor; Kytö, Mikko; Maye, Laura; McGookin, David; Bjartmarz, Ingibjörg; Arnadottir, Solveig A; Hjaltadóttir, Ingibjörg; Hafsteinsdóttir, Þóra B. (Springer Science and Business Media LLC, 2020-05-25)
    Background: Novel technical solutions are called for to promote home-based exercise among community-dwelling stroke survivors supported by their caregivers. Lack of resources and knowledge about how to accomplish it, has been demonstrated. The objective ...
  • Hrolfsdottir, Laufey; Halldorsson, Thorhallur; Birgisdottir, Bryndis Eva; Hreiðarsdóttir, Ingibjörg Th.; Hardardottir, Hildur; Gunnarsdottir, Ingibjorg (Wiley, 2018-07-23)
    Excessive gestational weight gain (GWG) is a risk factor for several adverse pregnancy outcomes, including macrosomia. Diet is one of the few modifiable risk factors identified. However, most dietary assessment methods are impractical for use in maternal ...
  • van der Roest, Henriëtte G.; Jónsson, Pálmi V. (Springer Science and Business Media LLC, 2019-05-15)
    Background: Europe's ageing society leads to an increased demand for long-term care, thereby putting a strain on the sustainability of health care systems. The 'Identifying best practices for care-dependent elderly by Benchmarking Costs and outcomes ...
  • Haraldsdottir, Alfheidur; Torfadottir, Johanna; Valdimarsdottir, Unnur; Adami, Hans-Olov; Aspelund, Thor; Tryggvadottir, Laufey; Þórðardóttir, Maríanna; Birgisdottir, Bryndis Eva; Harris, Tamara B.; Launer, Lenore J.; Gudnason, Vilmundur; Steingrimsdottir, Laufey (Public Library of Science (PLoS), 2018-05-30)
    Recent studies indicate that lifestyle factors in early life affect breast cancer risk. We therefore explored the association of high consumption of meat, milk, and whole grain products in adolescence and midlife, on breast cancer risk. We used data ...