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Fletta eftir efnisorði "Krabbamein"
Atriði 1-20 af 36
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(Springer Science and Business Media LLC, 2020-09-09)Background: Cancer patients have a highly increased risk of psychiatric disorders following diagnosis, compared with cancer-free individuals. Inflammation is involved in the development of both cancer and psychiatric disorders. The role of non-steroidal ... -
(University of Iceland, School of Engineering and Natural Sciences, Faculty of Physical Sciences, 2021-04)Application of external beam radiation therapy (EBRT) to localized cancer has long been regarded as a standard treatment option with its purpose being to deliver a ho- mogeneous high-dose distribution within the tumor volume while protecting organs at ...
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(Springer Science and Business Media LLC, 2020-06-13)Purpose: Obesity increases the risk of several cancers, but the influence of bariatric surgery on the risk of individual obesity-related cancers is unclear. This study aimed to assess the impact of bariatric surgery on cancer risk in a multi-national ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2023-11-16)ATG7, an essential protein for cellular homeostasis, plays a pivotal role in regulating autophagy. The autophagy process ensures the degradation and recycling of cellular components for proper cell function. ATG7 facilitates the lipidation of ATG8 ...
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(Cold Spring Harbor Laboratory, 2019-03-11)Coding variants in epigenetic regulators are emerging as causes of neurological dysfunction and cancer. However, a comprehensive effort to identify disease candidates within the human epigenetic machinery (EM) has not been performed; it is unclear ...
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(BMJ, 2017-06)Purpose To describe a newly created all-Nordic cohort of patients with gastro-oesophageal reflux disease (GORD), entitled the Nordic Antireflux Surgery Cohort (NordASCo), which will be used to compare participants having undergone antireflux surgery ...
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(Springer Nature, 2017-05-03)Lynch syndrome, caused by germline mutations in the mismatch repair genes, is associated with increased cancer risk. Here using a large whole-genome sequencing data bank, cancer registry and colorectal tumour bank we determine the prevalence of Lynch ...
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(Springer Nature, 2016-11-10)The objective of cancer treatment is to secure survival. However, as chemotherapeutic agents can affect the central and peripheral nervous systems, patients must undergo a process of central compensation. We explored the effectiveness of this compensation ...
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(University of Iceland, School of Health Sciences, Faculty of Nursing, 2021-06)Markmið: Markmið doktorsrannsóknarinnar var að lýsa stöðu þekkingar á meðferðarrannsóknum eftir greiningu og meðferð krabbameins sem ætlað er að draga úr kynlífsvanda og efla nánd hjá pörum. Ennfremur var markmiðið að þróa og meta árangur nýrrar ...
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(MDPI AG, 2018-12-13)Fluoropyrimidine-based chemotherapy is extensively used for the treatment of solid cancers, including colorectal cancer. However, fluoropyrimidine-driven toxicities are a major problem in the management of the disease. The grade and type of the ...
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(Springer Science and Business Media LLC, 2019-11-01)Breast cancer is a common disease partially caused by genetic risk factors. Germline pathogenic variants in DNA repair genes BRCA1, BRCA2, PALB2, ATM, and CHEK2 are associated with breast cancer risk. FANCM, which encodes for a DNA translocase, has ...
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(Springer Science and Business Media LLC, 2019-04-15)Genome-wide association studies (GWAS) have identified more than 170 breast cancer susceptibility loci. Here we hypothesize that some risk-associated variants might act in non-breast tissues, specifically adipose tissue and immune cells from blood and ...
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(Springer Nature, 2017-02-14)The great majority of thyroid cancers are of the non-medullary type. Here we report findings from a genome-wide association study of non-medullary thyroid cancer, including in total 3,001 patients and 287,550 controls from five study groups of European ...
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(Springer Science and Business Media LLC, 2018-11-08)Benign prostatic hyperplasia and associated lower urinary tract symptoms (BPH/LUTS) are common conditions affecting the majority of elderly males. Here we report the results of a genome-wide association study of symptomatic BPH/LUTS in 20,621 patients ...
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(Springer Science and Business Media LLC, 2020-02-10)Cutaneous squamous cell carcinoma (SCC) is one of the most common cancers in the United States. Previous genome-wide association studies (GWAS) have identified 14 single nucleotide polymorphisms (SNPs) associated with cutaneous SCC. Here, we report the ...
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(Læknafélag Íslands / Icelandic Medical Association, 2017-01-05)Hnútar í skjaldkirtli eru algengt vandamál og nýgengi þeirra hefur aukist mikið. Kerfisbundin nálgun við uppvinnslu er nauðsynleg til að greining fáist fljótt en ekki síður til að koma í veg fyrir ofgreiningu og ofmeðhöndlun sjúklinga. Það er mikilvægt ...
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(Springer Science and Business Media LLC, 2018-09-13)Genome-wide association studies (GWAS) have transformed our understanding of susceptibility to multiple myeloma (MM), but much of the heritability remains unexplained. We report a new GWAS, a meta-analysis with previous GWAS and a replication series, ...
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(Dove Medical Press Ltd., 2018-05)Background: A parental cancer diagnosis is a stressful life event, potentially leading to increased risks of mental and physical problems among children. This study aimed to investigate the associations of parental cancer with IQ, stress resilience, ...
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(Wiley, 2017-10-06)Objectives There are currently few data on the long‐term risk of cancer and death in individuals taking raltegravir (RAL). The aim of this analysis was to evaluate whether there is evidence for an association. Methods The EuroSIDA cohort was divided ...
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(Public Library of Science (PLoS), 2017-05-09)Background Survivors of childhood cancer are at increased risk for a wide range of late effects. However, no large population-based studies have included the whole range of somatic diagnoses including subgroup diagnoses and all main types of childhood ...
Atriði 1-20 af 36