Opin vísindi: Síðast bætt við

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    GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome 
    Simovski, Boris; Vodák, Daniel; Gundersen, Sveinung; Domanska, Diana; Azab, Abdulrahman; Holden, Lars; Holden, Marit; Grytten, Ivar; Rand, Knut; Drabløs, Finn; Johansen, Morten; Mora, Antonio; Lund-Andersen, Christin; Fromm, Bastian; Eskeland, Ragnhild; Gabrielsen, Odd Stokke; Ferkingstad, Egil; Nakken, Sigve; Bengtsen, Mads; Nederbragt, Alexander Johan; Thorarensen, Hildur Sif; Akse, Johannes Andreas; Glad, Ingrid; Hovig, Eivind; Sandve, Geir Kjetil (Oxford University Press (OUP), 2017-04-27)
    Background: Recent large-scale undertakings such as ENCODE and Roadmap Epigenomics have generated experimental data mapped to the human reference genome (as genomic tracks) representing a variety of functional elements across a large number of cell ...
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    Winter mass balance of Drangajökull ice cap (NW Iceland) derived from satellite sub-meter stereo images 
    Belart, Joaquín M. C.; Berthier, Etienne; Magnússon, Eyjólfur; Anderson, Leif S.; Pálsson, Finnur; Þorsteinsson, Þorsteinn; Howat, Ian M.; Adalgeirsdottir, Gudfinna; Jóhannesson, Tómas; Jarosch, Alexander H. (Copernicus GmbH, 2017-06-30)
    Sub-meter resolution, stereoscopic satellite images allow for the generation of accurate and high-resolution digital elevation models (DEMs) over glaciers and ice caps. Here, repeated stereo images of Drangajökull ice cap (NW Iceland) from Pléiades and ...
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    Transcriptional dynamics of a conserved gene expression network associated with craniofacial divergence in Arctic charr 
    Pashay Ahi, Ehsan; Kapralova, Kalina; Palsson, Arnar; Maier, Valerie; Guðbrandsson, Jóhannes; Snorrason, Sigurður S.; Jónsson, Zophonías Oddur; Franzdottir, Sigridur Rut (Springer Nature, 2014)
    Background Understanding the molecular basis of craniofacial variation can provide insights into key developmental mechanisms of adaptive changes and their role in trophic divergence and speciation. Arctic charr (Salvelinus alpinus) is a polymorphic ...
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    Differential expression of the aryl hydrocarbon receptor pathway associates with craniofacial polymorphism in sympatric Arctic charr 
    Pashay Ahi, Ehsan; Steinhäuser, Sophie S.; Palsson, Arnar; Franzdottir, Sigridur Rut; Snorrason, Sigurður S.; Maier, Valerie H.; Jónsson, Zophonías Oddur (Springer Nature, 2015-09-16)
    Background The developmental basis of craniofacial morphology hinges on interactions of numerous signalling systems. Extensive craniofacial variation in the polymorphic Arctic charr, a member of the salmonid family, from Lake Thingvallavatn (Iceland), ...
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    Quantum chemical calculation of electron ionization mass spectra for general organic and inorganic molecules 
    Ásgeirsson, Vilhjálmur; Bauer, Christoph A.; Grimme, Stefan (Royal Society of Chemistry (RSC), 2017)
    We introduce a fully stand-alone version of the Quantum Chemistry Electron Ionization Mass Spectra (QCEIMS) program [S. Grimme, Angew. Chem. Int. Ed., 2013, 52, 6306] allowing efficient simulations for molecules composed of elements with atomic numbers ...
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    CpG promoter methylation of the ALKBH3 alkylation repair gene in breast cancer 
    Stefansson, Olafur; Hermanowicz, Stefan; van der Horst, Jasper; Hilmarsdóttir, Hólmfríður; Staszczak, Zuzanna; Jónasson, Jón Gunnlaugur; Tryggvadottir, Laufey; Guðjónsson, Þorkell; Sigurðsson, Stefán (Springer Nature, 2017-07-05)
    Background DNA repair of alkylation damage is defective in various cancers. This occurs through somatically acquired inactivation of the MGMT gene in various cancer types, including breast cancers. In addition to MGMT, the two E. coli AlkB homologs ...
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    Non-skeletal health effects of vitamin D supplementation: A systematic review on findings from meta-analyses summarizing trial data 
    Rejnmark, Lars; Bislev, Lise Sofie; Cashman, Kevin D.; Eiríksdóttir, Guðný; Gaksch, Martin; Grübler, Martin; Grimnes, Guri; Gudnason, Vilmundur; Lips, Paul; Pilz, Stefan; van Schoor, Natasja M.; Kiely, Mairead; Jorde, Rolf (Public Library of Science (PLoS), 2017-07-07)
    Background A large number of observational studies have reported harmful effects of low 25-hydroxyvitamin D (25OHD) levels on non-skeletal outcomes. We performed a systematic quantitative review on characteristics of randomized clinical trials (RCTs) ...
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    The importance of accurate glacier albedo for estimates of surface mass balance on Vatnajökull: evaluating the surface energy budget in a regional climate model with automatic weather station observations 
    Schmidt, Louise Steffensen; Adalgeirsdottir, Gudfinna; Guðmundsson, Sverrir; Langen, Peter L.; Pálsson, Finnur; Mottram, Ruth; Gascoin, Simon; Björnsson, Helgi (Copernicus GmbH, 2017-07-14)
    A simulation of the surface climate of Vatnajökull ice cap, Iceland, carried out with the regional climate model HIRHAM5 for the period 1980–2014, is used to estimate the evolution of the glacier surface mass balance (SMB). This simulation uses a new ...
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    Facing unemployment: study protocol for the implementation and evaluation of a community-based intervention for psychological well-being promotion 
    Virgolino, Ana; Heitor, Maria João; Carreiras, Joana; Lopes, Elisa; Øverland, Simon; Torp, Steffen; Guðmundsdóttir, Dóra; Miguel, José Pereira; Fátima Reis, M.; Santos, Osvaldo (Springer Nature, 2017-07-19)
    Background Economic crises and unemployment have profound impact on mental health and well-being. Main goal of the Healthy Employment (HE) project is to enhance intersectoral actions promoting mental health among unemployed, namely through the ...
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    Maternal Macronutrient Intake and Offspring Blood Pressure 20 Years Later 
    Hrolfsdottir, Laufey; Halldorsson, Thorhallur; Rytter, Dorte; Bech, Bodil Hammer; Birgisdottir, Bryndis Eva; Gunnarsdottir, Ingibjorg; Granström, Charlotta; Henriksen, Tine Brink; Olsen, Sjurdur F.; Maslova, Ekaterina (Ovid Technologies (Wolters Kluwer Health), 2017-04)
    Background Results from 2 cohort studies in Scotland established in the 1940s and 1950s (Aberdeen and Motherwell) suggested that a high protein diet during pregnancy might adversely influence offspring blood pressure at adult age. Our objective was to ...
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    MEGGASENSE - The Metagenome/Genome Annotated Sequence Natural Language Search Engine: A Platform for the Construction of Sequence Data Warehouses 
    Gacesa, Ranko; Zucko, Jurica; Petursdottir, Solveig; Gudmundsdottir, Elisabet Eik; Fridjonsson, Olafur; Diminic, Janko; Long, Paul; Cullum, John; Hranueli, Daslav; Hreggvidsson, Gudmundur Oli; Starcevic, Antonio (Faculty of Food Technology and Biotechnology, University of Zagreb, Croatia, 2017-04)
    The MEGGASENSE platform constructs relational databases of DNA or protein sequences. The default functional analysis uses 14 106 hidden Markov model (HMM) profiles based on sequences in the KEGG database. The Solr search engine allows sophisticated queries ...
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    Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults 
    Graff, Mariaelisa; Scott, Robert A.; Justice, Anne E.; Young, Kristin L.; Feitosa, Mary F.; Barata, Llilda; Winkler, Thomas W.; Chu, Audrey Y.; Mahajan, Anubha; Hadley, David; Xue, Luting; Workalemahu, Tsegaselassie; Heard-Costa, Nancy L.; den Hoed, Marcel; Ahluwalia, Tarunveer S.; Qi, Qibin; Ngwa, Julius S.; Renström, Frida; Quaye, Lydia; Eicher, John D.; Hayes, James E.; Cornelis, Marilyn; Kutalik, Zoltán; Lim, Elise; Luan, Jian’an; Huffman, Jennifer E.; Zhang, Weihua; Zhao, Wei; Griffin, Paula J.; Haller, Toomas; Ahmad, Shafqat; Marques-Vidal, Pedro M.; Bien, Stephanie A.; Yengo, Loic; Teumer, Alexander; Smith, Albert Vernon; Kumari, Meena; Harder, Marie Neergaard; Justesen, Johanne Marie; Kleber, Marcus E.; Hollensted, Mette; Lohman, Kurt; Rivera, Natalia V.; Whitfield, John B.; Zhao, Jing Hua; Stringham, Heather M.; Lyytikäinen, Leo-Pekka; Huppertz, Charlotte; Willemsen, Gonneke; Peyrot, Wouter J.; Wu, Ying; Kristiansson, Kati; Demirkan, Ayse; Fornage, Myriam; Hassinen, Maija; Bielak, Lawrence F.; Cadby, Gemma; Tanaka, Toshiko; Mägi, Reedik; van der Most, Peter J.; Jackson, Anne U.; Bragg-Gresham, Jennifer L.; Vitart, Veronique; Marten, Jonathan; Navarro, Pau; Bellis, Claire; Pasko, Dorota; Johansson, Åsa; Snitker, Søren; Cheng, Yu-Ching; Eriksson, Joel; Lim, Unhee; Aadahl, Mette; Adair, Linda S.; Amin, Najaf; Balkau, Beverley; Auvinen, Juha; Beilby, John; Bergman, Richard N.; Bergmann, Sven; Bertoni, Alain G.; Blangero, John; Bonnefond, Amélie; Bonnycastle, Lori L.; Borja, Judith B.; Brage, Søren; Busonero, Fabio; Buyske, Steve; Campbell, Harry; Chines, Peter S.; Collins, Francis S.; Corre, Tanguy; Smith, George Davey; Delgado, Graciela E.; Dueker, Nicole; Dörr, Marcus; Ebeling, Tapani; Eiríksdóttir, Guðný; Esko, Tõnu; Faul, Jessica D.; Fu, Mao; Færch, Kristine; Gieger, Christian; Gläser, Sven; Gong, Jian; Gordon-Larsen, Penny; Grallert, Harald; Grammer, Tanja B.; Grarup, Niels; van Grootheest, Gerard; Harald, Kennet; Hastie, Nicholas D.; Havulinna, Aki S.; Hernandez, Dena; Hindorff, Lucia; Hocking, Lynne J.; Holmen, Oddgeir L.; Holzapfel, Christina; Hottenga, Jouke Jan; Huang, Jie; Huang, Tao; Hui, Jennie; Huth, Cornelia; Hutri-Kähönen, Nina; James, Alan L.; Jansson, John-Olov; Jhun, Min A.; Juonala, Markus; Kinnunen, Leena; Koistinen, Heikki A.; Kolcic, Ivana; Komulainen, Pirjo; Kuusisto, Johanna; Kvaløy, Kirsti; Kähönen, Mika; Lakka, Timo; Launer, Lenore J.; Lehne, Benjamin; Lindgren, Cecilia M.; Lorentzon, Mattias; Luben, Robert; Marre, Michel; Milaneschi, Yuri; Monda, Keri L.; Montgomery, Grant W.; De Moor, Marleen H. M.; Mulas, Antonella; Müller-Nurasyid, Martina; Musk, A.W.; Männikkö, Reija; Männistö, Satu; Narisu, Narisu; Nauck, Matthias; Nettleton, Jennifer A.; Nolte, Ilja M.; Oldehinkel, Albertine J.; Olden, Matthias; Ong, Ken K.; Padmanabhan, Sandosh; Paternoster, Lavinia; Perez, Jeremiah; Perola, Markus; Peters, Annette; Peters, Ulrike; Peyser, Patricia A.; Prokopenko, Inga; Puolijoki, Hannu; Raitakari, Olli T.; Rankinen, Tuomo; Rasmussen-Torvik, Laura J.; Rawal, Rajesh; Ridker, Paul M.; Rose, Lynda M.; Rudan, Igor; Sarti, Cinzia; Sarzynski, Mark A.; Savonen, Kai; Scott, William R.; Sanna, Serena; Shuldiner, Alan R.; Sidney, Steve; Silbernagel, Günther; Smith, Blair H.; Smith, Jennifer A.; Snieder, Harold; Stančáková, Alena; Sternfeld, Barbara; Swift, Amy J.; Tammelin, Tuija; Tan, Sian-Tsung; Thorand, Barbara; Thuillier, Dorothée; Vandenput, Liesbeth; Vestergaard, Henrik; van Vliet-Ostaptchouk, Jana V.; Vohl, Marie-Claude; Völker, Uwe; Waeber, Gérard; Walker, Mark; Wild, Sarah; Wong, Andrew; Wright, Alan F.; Zillikens, M. Carola; Zubair, Niha; Haiman, Christopher A.; Lemarchand, Loic; Gyllensten, Ulf; Ohlsson, Claes; Hofman, Albert; Rivadeneira, Fernando; Uitterlinden, André G.; Pérusse, Louis; Wilson, James F.; Hayward, Caroline; Polasek, Ozren; Cucca, Francesco; Hveem, Kristian; Hartman, Catharina A.; Tönjes, Anke; Bandinelli, Stefania; Palmer, Lyle J.; Kardia, Sharon L. R.; Rauramaa, Rainer; Sørensen, Thorkild I. A.; Tuomilehto, Jaakko; Salomaa, Veikko; Penninx, Brenda W. J. H.; de Geus, Eco J. C.; Boomsma, Dorret I.; Lehtimäki, Terho; Mangino, Massimo; Laakso, Markku; Bouchard, Claude; Martin, Nicholas G.; Kuh, Diana; Liu, Yongmei; Linneberg, Allan; März, Winfried; Strauch, Konstantin; Kivimäki, Mika; Harris, Tamara B.; Gudnason, Vilmundur; Völzke, Henry; Qi, Lu; Järvelin, Marjo-Riitta; Chambers, John C.; Kooner, Jaspal S.; Froguel, Philippe; Kooperberg, Charles; Vollenweider, Peter; Hallmans, Göran; Hansen, Torben; Pedersen, Oluf; Metspalu, Andres; Wareham, Nicholas J.; Langenberg, Claudia; Weir, David R.; Porteous, David J.; Boerwinkle, Eric; Chasman, Daniel I.; Abecasis, Gonçalo R.; Barroso, Inês; McCarthy, Mark I.; Frayling, Timothy M.; O’Connell, Jeffrey R.; van Duijn, Cornelia M.; Boehnke, Michael; Heid, Iris M.; Mohlke, Karen L.; Strachan, David P.; Fox, Caroline S.; Liu, Ching-Ti; Hirschhorn, Joel N.; Klein, Robert J.; Johnson, Andrew D.; Borecki, Ingrid B.; Franks, Paul W.; North, Kari E.; Cupples, L. Adrienne; Loos, Ruth J. F.; Kilpeläinen, Tuomas O. (Public Library of Science (PLoS), 2017-04-27)
    Physical activity (PA) may modify the genetic effects that give rise to increased risk of obesity. To identify adiposity loci whose effects are modified by PA, we performed genome-wide interaction meta-analyses of BMI and BMI-adjusted waist circumference ...
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    Plio-Pleistocene phylogeography of the Southeast Asian Blue Panchax killifish, Aplocheilus panchax 
    Beck, Samantha V.; Carvalho, Gary R.; Barlow, Axel; Rüber, Lukas; Hui Tan, Heok; Nugroho, Estu; Wowor, Daisy; Mohd Nor, Siti Azizah; Herder, Fabian; Muchlisin, Zainal A.; de Bruyn, Mark (Public Library of Science (PLoS), 2017-07-25)
    The complex climatic and geological history of Southeast Asia has shaped this region’s high biodiversity. In particular, sea level fluctuations associated with repeated glacial cycles during the Pleistocene both facilitated, and limited, connectivity ...
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    Artistic actions for sustainability : potential of art in education for sustainability 
    Jónsdóttir, Ásthildur B. (Lapland University Press, 2017)
    This review focuses on the potential of art in education for sustainability in the context of teacher education and art creation. Both action research and art-based research are used to explore the role that art and art education might play in Education ...
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    Economic Recession Affects Gambling Participation But Not Problematic Gambling: Results from a Population-Based Follow-up Study 
    Olason, Daniel; Hayer, Tobias; Meyer, Gerhard; Brosowski, Tim (Frontiers Media SA, 2017-07-25)
    In October 2008, Iceland experienced the fastest and deepest financial crisis recorded in modern times when all three major banks went bankrupt in less than 2 weeks. The purpose of this follow-up study is to examine potential changes in participation ...
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    Thyrotoxicosis in a 13-year-old girl following pituitary adenectomy for Cushing′s disease 
    Sigmarsdottir, Arndis; Ólafsson, Ingvar Hákon; Kjartansson, Olafur; Bjarnason, Ragnar Grímur (Wiley-Blackwell, 2017-07-06)
    Our objective is to report a case of thyrotoxicosis following pituitary adenectomy for Cushing0 s disease, the only pediatric case to our knowledge. No thyroid antibodies were detected, and the thyrotoxicosis was successfully treated for 3 months ...
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    Talent management in a microeconomy 
    Gudmundsdottir, Svala; Aðalsteinsson, Gylfi Dalmann; Helgudóttir, Jessica (Ardabil Industrial Management Institute, 2017)
    In recent years, there has been a growing interest in talent management, but there is still considerable debate with regard to understanding of the meaning of talent. While talent management has been criticized for the lack of conceptual and intellectual ...
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    Can life-cycle assessment produce reliable policy guidelines in the building sector? 
    Säynäjoki, Antti; Heinonen, Jukka; Junnila, Seppo; Horvath, Arpad (IOP Publishing, 2017-01-05)
    Life-cycle assessment (LCA) is an established methodology that can provide decision-makers with comprehensive data on the environmental impacts of products and processes during the entire life cycle. However, the literature on building LCAs consists ...
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    Pharmaceutical polymorph control in a drug-mimetic supramolecular gel 
    Foster, Jonathan A.; Damodaran, Krishna Kumar; Maurin, Antoine; Day, Graeme M.; Thompson, Hugh P. G.; Cameron, Gary J.; Bernal, Jenifer Cuesta; Steed, Jonathan W. (Royal Society of Chemistry (RSC), 2017)
    We report the synthesis of a bis(urea) gelator designed to specifically mimic the chemical structure of the highly polymorphic drug substance ROY. Crystallization of ROY from toluene gels of this gelator results in the formation of the metastable red ...
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    Secondary sclerosing cholangitis in critically ill patients: current perspectives 
    Guðnason, Hafsteinn Ó.; Björnsson, Einar Stefán (Dove Medical Press Ltd., 2017-06)
    Secondary sclerosing cholangitis (SSC) is a term used for a group of chronic cholestatic disease affecting the intra- and/or extrahepatic biliary tree with inflammation and progressive stricture formation, which can lead to biliary cirrhosis. A newly ...