Opin vísindi: Síðast bætt við

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    Premature menopause and autoimmune primary ovarian insufficiency in two international multi-center cohorts 
    Vogt, Elinor Chelsom; Real, Francisco Gómez; Husebye, Eystein Sverre; Björnsdottir, Sigridur; Benediktsdóttir, Bryndís; Bertelsen, Randi Jacobsen; Demoly, Pascal; Franklin, Karl Anders; Gallastegui, Leire Sainz de Aja; González, Francisco Javier Callejas; Heinrich, Joachim; Holm, Mathias; Jogi, Nils Oscar; Leynaert, Benedicte; Lindberg, Eva; Malinovschi, Andrei; Martínez-Moratalla, Jesús; Mayoral, Raúl Godoy; Oudin, Anna; Pereira-Vega, Antonio; Semjen, Chantal Raherison; Schlünssen, Vivi; Triebner, Kai; Øksnes, Marianne (2022-05)
    Objective: To investigate markers of premature menopause (<40 years) and specifically the prevalence of autoimmune primary ovarian insufficiency (POI) in European women. Design: Postmenopausal women were categorized according to age at menopause and ...
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    Fyrirkomulag og upplifun nemenda af matssamtali í raunfærnimati í leikskólakennarafræði við Háskóla Íslands 
    Hreinsdóttir, Anna Magnea; Sigurðardóttir, Ingibjörg Ósk (2022-10-31)
    Í þessari grein er fjallað um raunfærnimat í leikskólakennarafræði við Háskóla Íslands sem byggir á norrænni fyrirmynd. Umfjöllunin er afmörkuð við þróun matsgagna og aðferða í matssamtali í raunfærnimatinu til að meta þá þekkingu og hæfni sem nemendur ...
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    Screen Time and Body Image in Icelandic Adolescents : Sex-Specific Cross-Sectional and Longitudinal Associations 
    Hrafnkelsdottir, Soffia M.; Brychta, Robert J.; Rognvaldsdottir, Vaka; Chen, Kong Y.; Johannsson, Erlingur; Guðmundsdottir, Sigridur L.; Arngrimsson, Sigurbjorn A. (2022-01-24)
    Studies of adolescent body image and screen use are mostly limited to girls, and longitudinal data are scarce. We examined cross-sectional and longitudinal associations between these variables in mid-adolescent boys and girls. Data was collected when ...
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    Ideation, playful learning, and making in a Minecraft Virtual Learning Makerspace 
    Kjartansdóttir, Skúlína Hlíf; Þorsteinsson, Gisli; Kumpulainen, Kristiina; Kajamaa, Anu; Erstad, Ola; Mäkitalo, Åsa; Drotner, Kirsten; Jakobsdóttir, Sólveig (Routledge Taylor & Francis Group, 2022-07-05)
    This chapter discusses a study on Minecraft Virtual Learning Makerspace (MVLM), a virtual playground in an Icelandic rural school. The aim was to understand the pedagogy of using MVLM, focusing on learners’ ability to ideate and build in a playful ...
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    Quantifying the Effect of Wind on Volcanic Plumes: Implications for Plume Modeling 
    Dürig, Tobias; Guðmundsson, Magnús T.; Dioguardi, Fabio; Schmidt, Louise Steffensen (American Geophysical Union (AGU), 2023-01-13)
    The considerable effects that wind can have on estimates of mass eruption rates (MERs) in explosive eruptions based on volcanic plume height are well known but difficult to quantify rigorously. Many explicitly wind-affected plume models have the ...
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    Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology 
    Nielsen, K.R.; Pedersen, O.B.; Sørensen, E.; Ostrowski, S.; Johansson, P.I.; Gudbjartsson, D.; Stefansson, H.; Larsen, M.A.H.; Didriksen, M.; Sækmose, S.; Zeggini, E.; Hatzikotoulas, K.; Southam, L.; Gilly, A.; Barysenka, A.; van Meurs, J.B.J.; Boer, C.G.; Uitterlinden, A.G.; Styrkársdóttir, U.; Stefánsdóttir, L.; Esko, T.; Mägi, R.; Teder-Laving, M.; Ikegawa, S.; Terao, C.; Takuwa, H.; Meulenbelt, I.; Coutinho de Almeida, R.; Kloppenburg, M.; Tuerlings, M.; Slagboom, P.E.; Nelissen, R.R.G.H.H.; Valdes, A.M.; Mangino, M.; Tsezou, A.; Zengini, E.; Alexiadis, G.; Babis, G.C.; Cheah, K.S.E.; Wu, T.T.; Samartzis, D.; Cheung, J.P.Y.; Sham, P.C.; Kraft, P.; Kang, J.H.; Hveem, K.; Zwart, J.-A.; Luetge, A.; Skogholt, A.H.; Johnsen, M.B.; Thomas, L.F.; Winsvold, B.; Gabrielsen, M.E.; Lee, M.T.M.; Zhang, Y.; Lietman, S.A.; Shivakumar, M.; Smith, G.D.; Tobias, J.H.; Hartley, A.; Gaunt, T.R.; Zheng, J.; Wilkinson, J.M.; Steinberg, J.; Morris, A.P.; Ulfarsson, E.; Blondal, J.; Brunak, S.; Ostrowski, S.R.; Ullum, H.; Þorsteinsdóttir, U.; Stefansson, H.; Gudbjartsson, D.F.; Thorgeirsson, T.E.; Stefansson, K.; DBDS Genetic Consortium; GO Consortium (2022-02-02)
    Back pain is a common and debilitating disorder with largely unknown underlying biology. Here we report a genome-wide association study of back pain using diagnoses assigned in clinical practice; dorsalgia (119,100 cases, 909,847 controls) and ...
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    Incidence of Kidney Replacement Therapy and Subsequent Outcomes Among Patients With Systemic Lupus Erythematosus : Findings From the ERA Registry 
    Derner, Ondrej; Kramer, Anneke; Hruskova, Zdenka; Arici, Mustafa; Collart, Frederic; Finne, Patrik; Fuentes Sánchez, Laura; Harambat, Jérôme; Hemmelder, Marc H.; Hommel, Kristine; Kerschbaum, Julia; De Meester, Johan; Palsson, Runolfur; Segelmark, Mårten; Skrunes, Rannveig; Traynor, Jamie P.; Zurriaga, Oscar; Massy, Ziad A.; Jager, Kitty J.; Stel, Vianda S.; Tesar, Vladimir (2022-05)
    RATIONALE & OBJECTIVE: There is a dearth of data characterizing patients receiving kidney replacement therapy (KRT) for kidney failure due to systemic lupus erythematosus (SLE) and their clinical outcomes. The aim of this study was to describe trends ...
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    Framtíð sjúkrahúsþjónustu á Stór-Reykjavíkursvæðinu : Verður nýi meðferðarkjarninn skammgóður vermir? 
    Eyþórsson, Elías Sæbjörn; Guðmundsdóttir, Elísabet; Jónasdóttir, Kristlaug Helga; Pálsson, Runólfur (2022)
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    Associations of Pulmonary Function with MRI Brain Volumes : A Coordinated Multi-Study Analysis 
    Frenzel, Stefan; Bis, Joshua C.; Gudmundsson, Elias F.; O'Donnell, Adrienne; Simino, Jeannette; Yaqub, Amber; Bartz, Traci M.; Brusselle, Guy G.O.; Bülow, Robin; DeCarli, Charles S.; Ewert, Ralf; Gharib, Sina A.; Ghosh, Saptaparni; Gireud-Goss, Monica; Gottesman, Rebecca F.; Ikram, M. Arfan; Knopman, David S.; Launer, Lenore J.; London, Stephanie J.; Longstreth, W. T.; Lopez, Oscar L.; Melo van Lent, Debora; O'Connor, George; Satizabal, Claudia L.; Shrestha, Srishti; Sigurdsson, Sigurdur; Stubbe, Beate; Talluri, Rajesh; Vasan, Ramachandran S.; Vernooij, Meike W.; Völzke, Henry; Wiggins, Kerri L.; Yu, Bing; Beiser, Alexa S.; Gudnason, Vilmundur; Mosley, Thomas; Psaty, Bruce M.; Wolters, Frank J.; Grabe, Hans J.; Seshadri, Sudha (2022-11-22)
    BACKGROUND: Previous studies suggest poor pulmonary function is associated with increased burden of cerebral white matter hyperintensities and brain atrophy among elderly individuals, but the results are inconsistent. OBJECTIVE: To study the cross-sectional ...
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    Exploratory Investigation of the Plasma Proteome Associated with the Endotheliopathy of Trauma 
    Krocker, Joseph D.; Lee, Kyung Hyun; Henriksen, Hanne H.; Wang, Yao Wei Willa; Schoof, Erwin M.; Karvelsson, Sigurdur T.; Rolfsson, Óttar; Johansson, P. I.; Pedroza, Claudia; Wade, Charles E. (2022-06-01)
    Background: The endotheliopathy of trauma (EoT) is associated with increased mortality following injury. Herein, we describe the plasma proteome related to EoT in order to provide insight into the role of the endothelium within the systemic response ...
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    Association between service readiness and PMTCT cascade effectiveness : a 2018 cross-sectional analysis from Manica province, Mozambique 
    Dinis, Aneth; Augusto, Orvalho; Ásbjörnsdóttir, Kristjana H.; Crocker, Jonny; Gimbel, Sarah; Inguane, Celso; Ramiro, Isaías; Coutinho, Joana; Agostinho, Mery; Cruz, Emilia; Amaral, Fernando; Tavede, Esperança; Isidoro, Xavier; Sidat, Yaesh; Nassiaca, Regina; Murgorgo, Filipe; Cuembelo, Fátima; Hazim, Carmen E.; Sherr, Kenneth (2022-11-28)
    Background: Despite high coverage of maternal and child health services in Mozambique, prevention of mother-to-child transmission of HIV (PMTCT) cascade outcomes remain sub-optimal. Delivery effectiveness is modified by health system preparedness. ...
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    Neither low social support nor low decision latitude at work is associated with disease remission among patients with rheumatoid arthritis : results from the Swedish EIRA study 
    Hedenstierna, Louise; Hedström, Anna Karin; Klareskog, Lars; Di Giuseppe, Daniela; Alfredsson, Lars; Askling, Johan; Ernestam, Sofia; Saevarsdottir, Saedis; Ljung, Lotta (2022-08-23)
    Objectives: To investigate the association between psychosocial vulnerability, defined as either low social support or low decision latitude at work, and disease remission at 3, 12, and 60 months in patients with rheumatoid arthritis (RA). Methods: ...
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    Rate of SARS-CoV-2 Reinfection during an Omicron Wave in Iceland 
    Eythorsson, Elias; Runólfsdóttir, Hrafnhildur L.; Ingvarsson, Ragnar Freyr; Sigurðsson, Martin Ingi; Pálsson, Runólfur (2022-08-01)
    This cohort study estimates the proportion of persons who became reinfected with SARS-CoV-2 during the Omicron wave in Iceland.
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    Stafræn hæfni : Gagnsemi sjálfsmatsverkfæra og leiðarlykla í skólaþróun 
    Pétursdóttir, Svava; Þorsteinsdóttir, Þorbjörg St.; Jakobsdóttir, Sólveig (2022-11-12)
    Til að bregðast við breytingum sem fylgja stafrænni tækni og nýtingu hennar við nám og kennslu er í ýmsum stefnuskjölum lögð áhersla á hæfni kennara, starfsþróun og kennaramenntun. Evrópuráðið hefur sett fram ramma um stafræna hæfni í menntun (DigCompEdu ...
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    Antipsychotic use in pregnancy and risk of attention/deficit-hyperactivity disorder and autism spectrum disorder : a Nordic cohort study 
    Hálfdánarson, Óskar; Cohen, Jacqueline M.; Karlstad, Øystein; Cesta, Carolyn E.; Bjørk, Marte Helene; Håberg, Siri Eldevik; Einarsdóttir, Kristjana; Furu, Kari; Gissler, Mika; Hjellvik, Vidar; Kieler, Helle; Leinonen, Maarit K.; Nørgaard, Mette; Öztürk Essen, Buket; Ulrichsen, Sinna Pilgaard; Reutfors, Johan; Zoega, Helga (2022-05-01)
    BACKGROUND: Antipsychotics are increasingly used among women of childbearing age and during pregnancy. OBJECTIVE: To determine whether children exposed to antipsychotics in utero are at increased risk of attention-deficit/hyperactivity disorder (ADHD) ...
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    Prescription opioids among older adults : ten years of data across five countries 
    Hamina, A.; Muller, A. E.; Clausen, T.; Skurtveit, S.; Hesse, M.; Tjagvad, C.; Thylstrup, B.; Odsbu, I.; Zoega, H.; Jónsdóttir, Harpa Lind; Taipale, H. (2022-05-16)
    Abstract: Background: Opioid use has increased globally in the recent decade. Although pain remains a significant problem among older adults, susceptibility to opioid-related harms highlights the importance of careful opioid therapy monitoring on ...
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    Association of Maternal Autoimmune Diseases with Risk of Mental Disorders in Offspring in Denmark 
    He, Hua; Yu, Yongfu; Liew, Zeyan; Gissler, Mika; László, Krisztina D.; Valdimarsdóttir, Unnur Anna; Zhang, Jun; Li, Fei; Li, Jiong (2022-04-01)
    Importance: Maternal immune activation during pregnancy is associated with increased risks of several mental disorders in offspring during childhood, but little is known about how maternal autoimmune diseases during pregnancy are associated with mental ...
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    Neuroendocrine pathways and breast cancer progression : a pooled analysis of somatic mutations and gene expression from two large breast cancer cohorts 
    Hu, Kejia; Wang, Chengshi; Luo, Chuanxu; Zheng, Hong; Song, Huan; Bergstedt, Jacob; Fall, Katja; Luo, Ting; Czene, Kamila; Valdimarsdóttir, Unnur A.; Fang, Fang; Lu, Donghao (2022-06-21)
    Background: Experimental studies indicate that neuroendocrine pathways might play a role in progression of breast cancer. We aim to test the hypothesis that somatic mutations in the genes of neuroendocrine pathways influence breast cancer prognosis, ...
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    Perinatal mental health : how nordic data sources have contributed to existing evidence and future avenues to explore 
    Karalexi, Maria A.; Eberhard-Gran, Malin; Valdimarsdóttir, Unnur Anna; Karlsson, Hasse; Munk-Olsen, Trine; Skalkidou, Alkistis (2022-08)
    Purpose: Perinatal mental health disorders affect a significant number of women with debilitating and potentially life-threatening consequences. Researchers in Nordic countries have access to high quality, population-based data sources and the possibility ...
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    Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset 
    Sævarsdóttir, Sædís; Stefansdottir, Lilja; Sulem, P.; Thorleifsson, G.; Ferkingstad, E.; Rutsdottir, G.; Glintborg, B.; Westerlind, H.; Gröndal, Gerður María; Loft, I.C.; Sorensen, S.B.; Lie, B.A.; Brink, M.; Arlestig, L.; Arnthorsson, A.O.; Baecklund, E.; Banasik, K.; Bank, S.; Bjorkman, L.I.; Ellingsen, T.; Erikstrup, C.; Frei, O.; Gjertsson, I.; Gudbjartsson, D.F.; Gudjonsson, S.A.; Halldorsson, G.H.; Hendricks, O.; Hillert, J.; Hogdall, E.; Jacobsen, Sø; Jensen, D.V.; Jonsson, Helgi; Kastbom, A.; Kockum, I.; Kristensen, S.; Kristjansdottir, Helga; Larsen, M.H.; Linauskas, A.; Hauge, E.-M.; Loft, A.G.; Lúðvíksson, Björn Rúnar; Lund, S.H.; Markusson, Þorsteinn; Masson, G.; Melsted, P.; Moore, K.H.S.; Munk, H.; Nielsen, K.R.; Norddahl, G.L.; Oddsson, A.; Olafsdottir, T.A.; Olason, P.I.; Olsson, T.; Ostrowski, S.R.; Hørslev-Petersen, K.; Rognvaldsson, S.; Sanner, H.; Silberberg, G.N.; Stefansson, H.; Sørensen, E.; Sørensen, I.J.; Turesson, C.; Bergman, T.; Alfredsson, L.; Kvien, T.K.; Brunak, Sø; Steinsson, K.; Andersen, V.; Andreassen, O.A.; Rantapää-Dahlqvist, S.; Hetland, M.L.; Klareskog, L.; Askling, J.; Padyukov, L.; Pedersen, O.B.V.; Thorsteinsdottir, U.; Jonsdottir, I.; Stefánsson, Kári (2022-04-25)
    Objectives To find causal genes for rheumatoid arthritis (RA) and its seropositive (RF and/or ACPA positive) and seronegative subsets. Methods We performed a genome-wide association study (GWAS) of 31 313 RA cases (68% seropositive) and ∼1 million ...