Insect bite hypersensitivity (IBH) is a type I allergy of horses with production of IgE and release of inflammatory mediators. It is caused by bites of midges of the genus Culicoides. The disease is a recurrent dermatitis characterized by pruritic skin ...

Idiopathic pulmonary fibrosis is a severe lung disease with unknown aetiology. The lifespan is approximately 3 to 5 years after diagnosis, and the treatments available such as lung transplant are high risk and are not suitable for all patients. In ...

Abstract Psoriasis is a chronic immune-mediated inflammatory skin disease with profound effects on psychosocial wellbeing. Narrowband UVB phototherapy is a known effective treatment for chronic plaque psoriasis and previous studies suggest an ...

Introduction and aims: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and its complex pathophysiology is incompletely understood. At the time of beginning of this work, genome-wide association studies (GWAS) on AF had yielded ...

Background: Various theories regarding the link between emotion dysregulation and Oppositional Defiant Disorder symptoms are presented in the current literature. Firstly, with ODD now being viewed as a multi-dimensional construct placing irritability ...

Purpose and aims: Multiple sclerosis (MS) is an autoimmune disease that leads to damage in the central nervous system. Although the cause of MS is still unknown, the generally accepted view is that environmental and life-style factors influence the ...

Þekkt er að kæling frumna (32-36°C) eykur tjáningu fáeinna þekktra gena. Margt er á huldu um þá innanfrumu- og millifrumuferla sem kæling snertir við og kallaðir hafa verið kælisvarið. Kæling er notuð í læknisfræðilegum tilgangi til að fá fram ...

Epitranscriptomics refers to post-transcriptional regulation of gene expression via RNA modifications, which can affect the function and structure of RNAs but do not entail any changes to the ribonucleotide sequence. RNA modifications are found on all ...

Mælingar á fíkniefnum og lyfseðilsskyldum lyfjum í frárennslisvatni hafa undanfarin ár verið notaðar til þess að meta notkun efnanna. Aðferðafræðin byggir á þeirri kenningu að hægt sé að líta á frárennslisvatn sem samansafn þvagsýna frá heilu samfélagi. ...

Mesenchymal stromal cells (MSC) are promising candidates for cellular therapy due to their ability to regenerate bone and cartilage and modulate immune responses. The use of MSC in cellular therapy is problematic due to the need for fetal bovine serum ...