The aim of this study was to develop a stable aqueous formulation containing a combination of doxycycline and monocaprin in clinically relevant concentrations. Increase in expression of Matrix metalloproteinases (MMPs) and microbial role in oral ...

Fluoropyrimidine-based chemotherapy is extensively used for the treatment of solid cancers, including colorectal cancer. However, fluoropyrimidine-driven toxicities are a major problem in the management of the disease. The grade and type of the ...

This paper examines the story of the last female drifters in Iceland from the voices of women who remembered them. It examines the advantages of the woman-on-woman oral history interview when obtaining women’s perspectives on women’s history. An ...

The effectiveness of a drug treatment regimen relies on the efficient delivery to afflicted target areas. Drug delivery devices aim to achieve a sustained release and maintain a steady drug concentration level that falls within a therapeutic range. ...

A subgroup of patients treated with infliximab lose response to the treatment and one reason for this is the development of anti-drug antibodies (ADA). If used optimally, measuring drug and ADA level could lead to a more personalized and efficient ...

In this study we have developed biodegradable polymeric nanoparticles (NPs) containing the cytostatic drugs mertansine (MRT) or cabazitaxel (CBZ). The NPs are based on chitosan (CS) conjugate polymers synthesized with different amounts of the photosensitizer ...

The TACSI trial (ClinicalTrials.gov Identifier: NCT03560310) tests the hypothesis that 1-year treatment with dual antiplatelet therapy with acetylsalicylic acid (ASA) and ticagrelor is superior to only ASA after isolated coronary artery bypass grafting ...

This article explores the working conditions of Icelandic local councillors in relation to voluntary retirement from the council. In the past three elections, the turnover in councils has been very high, with approximately six out of every 10 council ...

Ein leið til að sinna mannkostamenntun er að lesa bókmenntir og greina og ræða mannkosti í þeim með nemendum. Í þessari grein er fjallað um forsendur þess að nota Íslendingasögur til mannkostamenntunar með nemendum á unglingsaldri. Rætt er um mikilvægi ...

Helical edge states of two-dimensional topological insulators show a gap in the density of states (DOS) and suppressed conductance in the presence of ordered magnetic impurities. Here we will consider the dynamical effects on the DOS and transmission ...