This is the digital repository for peer reviewed articles published in open access by the Agricultural University of Iceland, the Iceland Academy of the Arts, the National and University Library of Iceland, Reykjavik University, the University of Akureyri, Bifröst University, Hólar University College and the University of Iceland. Open access to research results is in accordance with article 10 from the Act on public support for research / 2003 No 3 and is compliant with requirements from international and domestic research fund programs. The purpose of the Open Science repository is to make results of research conducted at Icelandic universities accessible to the public online without hindrance or charge. Deposits to the repository are permanent and are intended to ensure future access to all published scientific material of the Icelandic research community. By collecting this material together in one collection access is made simple and easy for anyone who wishes to study the considerable scientific work conducted in Iceland.

The repository is OpenAIRE / OpenAIREplus compliant and in accordance with requirements for publication of research results from projects supported by the European research programs FP7 and H2020.

The repository uses the open software DSpace.

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    Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism 
    Sapkota, Yadav; Steinthorsdottir, Valgerdur; Morris, Andrew P.; Fassbender, Amelie; Rahmioglu, Nilufer; De Vivo, Immaculata; Buring, Julie E.; Zhang, Futao; Edwards, Todd L.; Jones, Sarah; O, Dorien; Peterse, Daniëlle; Rexrode, Kathryn M.; Ridker, Paul M.; Schork, Andrew J.; MacGregor, Stuart; Martin, Nicholas G.; Becker, Christian M.; Adachi, Sosuke; Yoshihara, Kosuke; Enomoto, Takayuki; Takahashi, Atsushi; Kamatani, Yoichiro; Matsuda, Koichi; Kubo, Michiaki; Þorleifsson, Guðmar; Geirsson, Reynir T.; Thorsteinsdottir, Unnur; Wallace, Leanne M.; Werge, Thomas M.; Thompson, Wesley K.; Yang, Jian; Velez Edwards, Digna R.; Nyegaard, Mette; Low, Siew-Kee; Zondervan, Krina T.; Missmer, Stacey A.; D'Hooghe, Thomas; Montgomery, Grant W.; Chasman, Daniel I.; Stefánsson, Kári; Tung, Joyce Y.; Nyholt, Dale R. (Springer Nature, 2017-05-24)
    Endometriosis is a heritable hormone-dependent gynecological disorder, associated with severe pelvic pain and reduced fertility; however, its molecular mechanisms remain largely unknown. Here we perform a meta-analysis of 11 genome-wide association ...
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    Feather holes of rock ptarmigan are associated with amblyceran chewing lice 
    Stenkewitz, Ute; Nielsen, Ólafur K.; Skirnisson, Karl; Stefansson, Gunnar (Bio One, 2017-06)
    Feather holes have traditionally been suggested to be feeding traces of chewing lice (mallophagans). There is controversy whether mallophagans are the real source of feather holes. We studied mallophagan infestations and holes in tail feathers of 528 ...
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    Metabolic Profiling as a Screening Tool for Cytotoxic Compounds: Identification of 3-Alkyl Pyridine Alkaloids from Sponges Collected at a Shallow Water Hydrothermal Vent Site North of Iceland 
    Einarsdóttir, Eydís; Magnúsdóttir, Manuela; Astarita, Giuseppe; Köck, Matthias; Ögmundsdóttir, Helga M.; Þorsteinsdóttir, Margrét; Rapp, Hans; Omarsdottir, Sesselja; Paglia, Giuseppe (MDPI AG, 2017-02-22)
    Twenty-eight sponge specimens were collected at a shallow water hydrothermal vent site north of Iceland. Extracts were prepared and tested in vitro for cytotoxic activity, and eight of them were shown to be cytotoxic. A mass spectrometry (MS)-based ...
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    Shock induced endotheliopathy (SHINE) in acute critical illness - a unifying pathophysiologic mechanism 
    Johansson, Pär Ingemar; Stensballe, Jakob; Ostrowski, SisseRye (Springer Nature, 2017-02-09)
    One quarter of patients suffering from acute critical illness such as severe trauma, sepsis, myocardial infarction (MI) or post cardiac arrest syndrome (PCAS) develop severe hemostatic aberrations and coagulopathy, which are associated with excess ...
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    The use of viscoelastic haemostatic assays in goal-directing treatment with allogeneic blood products – A systematic review and meta-analysis 
    Fahrendorff, Mathilde; Oliveri, Roberto S.; Johansson, Pär Ingemar (Springer Nature, 2017-04-13)
    Background Management of the critically bleeding patient can be encountered in many medical and surgical settings. Common for these patients is a high risk of dying from exsanguination secondary to developing coagulopathy. The purpose of this meta-analysis ...

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