Opin vísindi: Recent submissions

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    The contribution of individual items to the global ensemble representation 
    Iakovlev, Aleksei (University of Iceland, School of Health Sciences, Faculty of Psychology, 2024-12-03)
    In daily life, people often see groups of similar objects compressed into a single percept. For instance, many people standing together form a crowd, and individual cars moving along the road form traffic. The general impression of traffic speed or ...
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    Standardised and hierarchically classified heart failure and complementary disease monitoring outcome measures : european Unified Registries for heart Care evaluation and randomised trials (EuroHeart) 
    Bhatty, Asad; Wilkinson, Chris; Batra, Gorav; Aktaa, Suleman; Smith, Adam B; Wahab, Ali; Chappell, Sam; Alfredsson, Joakim; Erlinge, David; Ferreira, Jorge; Guðmundsdóttir, Ingibjörg Jóna; Hrafnkelsdóttir, Þórdís Jóna; Ingimarsdóttir, Inga Jóna; Irs, Alar; Jánosi, András; Járai, Zoltán; Oliveira-Santos, Manuel; Popescu, Bogdan A; Vasko, Peter; Vinereanu, Dragos; Yap, Jonathan; Bugiardini, Raffaele; Cenko, Edina; Nadarajah, Ramesh; Sydes, Matthew R; James, Stefan; Maggioni, Aldo P; Wallentin, Lars; Casadei, Barbara; Gale, Chris P (2024-10-09)
    AIMS: The lack of standardised definitions for heart failure outcome measures limits the ability to reliably assess effectiveness of heart failure therapies. The European Unified Registries for Heart Care Evaluation and Randomised Trials (EuroHeart) ...
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    Representation of the ICF in research of speech intelligibility : A systematic review of literature describing deaf and hard-of-hearing children 
    Magnússon, Egill; Crowe, Kathryn Margaret; Stefánsdóttir, Harpa; Guiberson, Mark; Másdóttir, Thora; Ágústsdóttir, Inga; Baldursdóttir, Ösp Vilberg (2024-11-01)
    PURPOSE: The purpose of this review was to map speech intelligibility measures used for assessing d/Deaf and hard-of-hearing children onto the International Classification of Functioning, Disability and Health. METHOD: This review considered perceptual ...
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    Birth satisfaction and symptoms of childbirth related PTSD among women in Iceland : A population-based study 
    Swift, Emma Marie; Guðmundsdóttir, Fjóla; Einarsdóttir, Kristjana; Sigurðardóttir, Valgerður Lísa (2024-12)
    Background: Given its complexity, childbirth can elicit both positive and negative psychological reactions and, in some cases, women may experience symptoms of childbirth-related post-traumatic stress disorder (CB-PTSD). Several risk factors for CB-PTSD ...
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    Verbal memory is linked to average oxygen saturation during sleep, not the apnea-hypopnea index nor novel hypoxic load variables 
    Thorisdottir, K.; Hrubos-Strøm, H.; Karhu, T.; Nikkonen, S.; Dammen, T.; Nordhus, I. H.; Leppänen, T.; Jónsdóttir, María Kristín; Arnardóttir, Erna Sif (2024-11)
    Introduction: The apnea-hypopnea index (AHI) is the current diagnostic parameter for diagnosing and estimating the severity of obstructive sleep apnea (OSA). It is, however, poorly associated with the main clinical symptom of OSA, excessive daytime ...
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    Kidney transplantation in Icelandic patients, 2000–2019 : are outcomes affected by low volume? 
    Pálsson, Þórður Páll; Andrésdóttir, Margrét Birna; Jónsson, Eiríkur; Jónsson, Jóhann; Hilmarsson, Rafn; Indriðason, Ólafur Skúli; Pálsson, Runólfur (2024-05-28)
    Background: In Iceland, a small number of kidney transplants from living donors (LDs) are performed at Landspitali University Hospital (LUH) in Reykjavik, while deceased donor transplants have until recently invariably been carried out abroad. In this ...
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    Mortality in Community-Acquired Sepsis and Infections in the Faroe Islands—A Prospective Observational Study 
    Todorovic Markovic, Marija; Todorovic Mitic, Mirjana; Ignjatovic, Aleksandra; Gottfreðsson, Magnús; Gaini, Shahin (2024-05-13)
    The aim of this study was to collect data and analyze mortality among patients hospitalized with community-acquired infections in the Faroe Islands. A prospective observational study was conducted in the Medical Department of the National Hospital of ...
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    A partial loss-of-function variant in STAT6 protects against type 2 asthma 
    Kristjansdottir, Katla; Norddahl, Gudmundur L; Ivarsdottir, Erna V; Halldórsson, Gísli Hreinn; Einarsson, Gudmundur; Bjarnadottir, Kristbjorg; Rutsdottir, Gudrun; Arnthorsson, Asgeir O; Erikstrup, Christian; Gudmundsdottir, Steinunn; Gunnarsdottir, Kristbjorg; Gunnbjörnsdóttir, María I; Halldórsson, Bjarni Vilhjálmur; Holm, Hilma; Lúðvíksdóttir, Dóra; Lúðvíksson, Björn Rúnar; Brunak, Søren; Bruun, Mie Topholm; Mikkelsen, Christina; Mikkelsen, Susan; Jensen, Bitten Aagaard; Sørensen, Erik; Thomsen, Simon Francis; Ullum, Henrik; Ólafsson, Ísleifur; Önundarson, Páll Torfi; Ostrowski, Sisse Rye; Sævarsdóttir, Sædís; Sigurdardottir, Olof; Sigurgeirsson, Bardur; Snaebjarnarson, Audunn S; Sveinbjornsson, Gardar; Thorlacius, Gudny E; Thorleifsson, Gudmar; Tragante, Vinicius; Vidarsson, Brynjar; Porsbjerg, Celeste; Björnsdóttir, Unnur Steina; Sulem, Patrick; Gudbjartsson, Daniel F; Melsted, Páll; Pedersen, Ole Bv; Jónsdóttir, Ingileif; Olafsdottir, Thorunn A; Stefánsson, Kári (2024-10-16)
    BACKGROUND: Signal transducer and activator of transcription 6 (STAT6) is central to type 2 (T2) inflammation, and common noncoding variants at the STAT6 locus associate with various T2 inflammatory traits, including diseases, and its pathway is widely ...
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    Sequence variants associated with BMI affect disease risk through BMI itself 
    Einarsson, Gudmundur; Thorleifsson, Gudmar; Steinthorsdottir, Valgerdur; Zink, Florian; Helgason, Hannes; Olafsdottir, Thorhildur; Rognvaldsson, Solvi; Tragante, Vinicius; Ulfarsson, Magnus O; Sveinbjornsson, Gardar; Snaebjarnarson, Audunn S; Einarsson, Hafsteinn; Ægisdóttir, Hildur Margrét; Jonsdottir, Gudrun A; Helgadottir, Anna; Gretarsdottir, Solveig; Styrkarsdottir, Unnur; Arnason, Hannes K; Bjarnason, Ragnar Grímur; Sigurdsson, Emil; Arnar, Davíð Ottó; Björnsson, Einar Stefán; Pálsson, Runólfur; Bjornsdottir, Gyda; Stefansson, Hreinn; Thorgeirsson, Thorgeir; Sulem, Patrick; Þorsteinsdóttir, Unnur; Holm, Hilma; Gudbjartsson, Daniel F; Stefánsson, Kári (2024-11-12)
    Mendelian Randomization studies indicate that BMI contributes to various diseases, but it's unclear if this is entirely mediated by BMI itself. This study examines whether disease risk from BMI-associated sequence variants is mediated through BMI or ...
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    Prospective study of risk factors for community-acquired acute kidney injury 
    Ragnarsdotttir, Telma Huld; Kristjánsdóttir, Margrét Kristín; Gíslason, Gísli; Sanchez-Brunete, Vicente; Tómasdóttir, Margrét Ólafía; Samúelsson, Ólafur Helgi; Pálsson, Runólfur; Indriðason, Ólafur Skúli (2024)
    Background and hypothesis: Causes and risk factors for community-acquired acute kidney injury (CA-AKI) have not been thoroughly studied. The aim of this study was to examine the risk factors for CA-AKI. Methods: In this prospective study, we examined ...
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    Diagnostic and therapeutic practice for HFpEF across continents and regions : An international survey 
    Ingimarsdóttir, Inga Jóna; Vishram-Nielsen, Julie K.K.; Einarsson, Hafsteinn; Goldfeder, Sidney; Mewton, Nathan; Barasa, Anders; Basic, Carmen; Oerlemans, Marish I.F.J.; Niederseer, David; Shchendrygina, Anastasia; Gustafsson, Finn; Ruschitzka, Frank; Kida, Keisuke; Mohty, Dania; Rakotonoel, Rolland R.; Tun, Han Naung; Hrafnkelsdóttir, Þórdís Jóna; Saldarriaga, Clara (2024-10-01)
    Aims: This study aims to evaluate the worldwide variations in the diagnosis and treatment of heart failure with preserved ejection fraction (HFpEF), using an HF survey distributed internationally to physicians, including both cardiologists and ...
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    Gene content, phage cycle regulation model and prophage inactivation disclosed by prophage genomics in the Helicobacter pylori Genome Project 
    HpGP Research Network; Harðardóttir, Hjördís; Gunnarsdóttir, Anna Ingibjörg; Guðjónsson, Hallgrímur; Jónasson, Jón Gunnlaugur; Björnsson, Einar Stefán (2024)
    Prophages can have major clinical implications through their ability to change pathogenic bacterial traits. There is limited understanding of the prophage role in ecological, evolutionary, adaptive processes and pathogenicity of Helicobacter pylori, a ...
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    Eco-evolutionary processes in personality and spatial cognition of Arctic charr morphs (Salvelinus alpinus) 
    Dellinger, Marion (University of Iceland, Faculty of Life and Environmental Sciences, School of Engineering and Natural Sciences, 2024-11-29)
    Behaviour is a fascinatingly flexible phenotype with immense diversity of manifestations. Despite this diversity, observation of animals makes it evident that individuals show consistent differences from one another in the way they behave. However, ...
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    Inhaled analgesics for the treatment of prehospital acute pain-A systematic review 
    Hyldmo, Per Kristian; Rehn, Marius; Dahl Friesgaard, Kristian; Rognås, Leif; Raatiniemi, Lasse; Kurola, Jouni; Larsen, Robert; Kongstad, Poul; Sandberg, Mårten; Magnússon, Viðar; Vist, Gunn Elisabeth (2024-11)
    BACKGROUND: Many prehospital emergency patients receive suboptimal treatment for their moderate to severe pain. Various factors may contribute. We aim to systematically review literature pertaining to prehospital emergency adult patients with acute ...
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    Cerebrovascular and Alzheimer's disease biomarkers in dementia with Lewy bodies and other dementias 
    Rennie, Anna; Ekman, Urban; Shams, Sara; Rydén, Lina; Samuelsson, Jessica; Zettergren, Anna; Kern, Silke; Oppedal, Ketil; Blanc, Frédéric; Hort, Jakub; Garcia-Ptacek, Sara; Antonini, Angelo; Lemstra, Afina W; Padovani, Alessandro; Kramberger, Milica Gregoric; Rektorová, Irena; Walker, Zuzana; Snædal, Jón G; Pardini, Matteo; Taylor, John-Paul; Bonanni, Laura; Granberg, Tobias; Aarsland, Dag; Skoog, Ingmar; Wahlund, Lars-Olof; Kivipelto, Miia; Westman, Eric; Ferreira, Daniel (2024-08-28)
    Co-pathologies are common in dementia with Lewy bodies and other dementia disorders. We investigated cerebrovascular and Alzheimer's disease co-pathologies in patients with dementia with Lewy bodies in comparison with patients with mild cognitive ...
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    Genome-Wide Association Study Meta-Analysis of 9619 Cases With Tic Disorders 
    PGC TS Working Group (2024-10-09)
    BACKGROUND: Despite the significant personal and societal burden of tic disorders (TDs), treatment outcomes remain modest, necessitating a deeper understanding of their etiology. Family history is the biggest known risk factor, and identifying risk ...
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    Sequence variants influencing the regulation of serum IgG subclass levels 
    Ólafsdóttir, Þórunn Ásta; Thorleifsson, Gudmar; Lopez de Lapuente Portilla, Aitzkoa; Jonsson, Stefan; Stefánsdóttir, Lilja; Niroula, Abhishek; Jonasdottir, Aslaug; Eggertsson, Hannes P.; Halldórsson, Gísli Hreinn; Thorlacius, Gudny E.; Arnthorsson, Asgeir O.; Björnsdóttir, Unnur Steina; Asselbergs, Folkert W.; Bentlage, Arthur E.H.; Eyjolfsson, Gudmundur I.; Gudmundsdottir, Steinunn; Gunnarsdottir, Kristbjorg; Halldórsson, Bjarni Vilhjálmur; Holm, Hilma; Lúðvíksson, Björn Rúnar; Melsted, Páll; Norddahl, Gudmundur L.; Ólafsson, Ísleifur; Saevarsdottir, Saedis; Sigurdardottir, Olof; Sigurdsson, Asgeir; Temming, Robin; Önundarson, Páll Torfi; Þorsteinsdóttir, Unnur; Vidarsson, Gestur; Sulem, Patrick; Gudbjartsson, Daniel F.; Jónsdóttir, Ingileif; Nilsson, Björn; Stefánsson, Kári (2024-12)
    Immunoglobulin G (IgG) is the main isotype of antibody in human blood. IgG consists of four subclasses (IgG1 to IgG4), encoded by separate constant region genes within the Ig heavy chain locus (IGH). Here, we report a genome-wide association study on ...
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    Promoter CpG Density Predicts Downstream Gene Loss-of-Function Intolerance 
    Boukas, Leandros; Björnsson, Hans Tómas; Hansen, Kasper D. (2020-09-03)
    The aggregation and joint analysis of large numbers of exome sequences has recently made it possible to derive estimates of intolerance to loss-of-function (LoF) variation for human genes. Here, we demonstrate strong and widespread coupling between ...
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    A PSA SNP associates with cellular function and clinical outcome in men with prostate cancer 
    The IMPACT Study; The PROFILE Study Steering Committee; The PRACTICAL consortium; The Australian Prostate Cancer BioResource (2024-11-06)
    Genetic variation at the 19q13.3 KLK locus is linked with prostate cancer susceptibility in men. The non-synonymous KLK3 single nucleotide polymorphism (SNP), rs17632542 (c.536 T > C; Ile163Thr-substitution in PSA) is associated with reduced prostate ...
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    Perinatal death in the Nordic countries in relation to gestational age : The impact of registration practice 
    Jeppegaard, Maria; Frølich, Maria Kongerslev; Thomsen, Liv Cecilie Vestrheim; Heino, Anna; Liu, Eileen; Gunnarsdóttir, Jóhanna; Akerkar, Rupali Rajendra; Eskildsen, Lene Friis; Källén, Karin; Ohlin, Mikael; Klungsøyr, Kari; Gissler, Mika; Krebs, Lone (2024-11-05)
    Introduction: Although perinatal death rates in the Nordic countries are among the lowest in the world, the risk of perinatal death is unevenly distributed across the Nordic countries, despite similarity in health care systems and pregnancy care. Birth ...