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    A polygenic resilience score moderates the genetic risk for schizophrenia 
    Hess, Jonathan L.; Sigurdsson, Engilbert; Stefansson, Hreinn; Stefansson, Kari (Springer Science and Business Media LLC, 2019-09-06)
    Based on the discovery by the Resilience Project (Chen R. et al. Nat Biotechnol 34:531–538, 2016) of rare variants that confer resistance to Mendelian disease, and protective alleles for some complex diseases, we posited the existence of genetic variants ...
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    Polygenic risk scores for schizophrenia and bipolar disorder associate with addiction 
    Reginsson, Gunnar W.; Ingason, Andrés; Euesden, Jack; Bjornsdottir, Gyda; Ólafsson, Sigurgeir; Sigurdsson, Engilbert; Óskarsson, Högni; Tyrfingsson, Þórarinn; Rúnarsdóttir, Valgerður; Hansdóttir, Ingunn; Steinberg, Stacy; Stefánsson, Hreinn; Gudbjartsson, Daniel; Thorgeirsson, Thorgeir; Stefansson, Kari (Wiley, 2017-02-23)
    We use polygenic risk scores (PRSs) for schizophrenia (SCZ) and bipolar disorder (BPD) to predict smoking, and addiction to nicotine, alcohol or drugs in individuals not diagnosed with psychotic disorders. Using PRSs for 144 609 subjects, including 10 ...
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    Population distribution of traditional and the emerging cardiovascular risk factors carotid plaque and IMT: the REFINE-Reykjavik study with comparison with the Tromsø study 
    Thorsson, Bolli; Eiriksdottir, Gudny; Sigurðsson, Sigurður; Guðmundsson, Elías Freyr; Bots, Michael L; Aspelund, Thor; Arntzen, Kjell Arne; Mathiesen, Ellisiv B; Gudnason, Vilmundur (BMJ, 2018-05-01)
    Objectives Population statistics for carotid plaque and cardiovascular risk factors reported in scientific journals are usually presented as averages for the population or age and sex adjusted, rather than sex and age groups. Important population ...
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    Population Genomic Molecular Epidemiological Study of Macrolide-Resistant Streptococcus pyogenes in Iceland, 1995 to 2016: Identification of a Large Clonal Population with a pbp2x Mutation Conferring Reduced In Vitro β-Lactam Susceptibility 
    Southon, Sara B.; Beres, Stephen B.; Kachroo, Priyanka; Saavedra, Matthew Ojeda; Erlendsdóttir, Helga; Haraldsson, Gunnsteinn; Yerramilli, Prasanti; Pruitt, Layne; Zhu, Luchang; Musser, James M.; Kristinsson, Karl G. (American Society for Microbiology, 2020-06-10)
    Resistance to macrolide antibiotics is a global concern in the treatment of Streptococcus pyogenes (group A Streptococcus [GAS]) infections. In Iceland, since the detection of the first macrolide-resistant isolate in 1998, three epidemic waves of ...
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    Population structure of Purple Sandpipers (Calidris maritima) as revealed by mitochondrial DNA and microsatellites 
    LeBlanc, Nathalie M.; Stewart, Donald T.; Pálsson, Snæbjörn; Elderkin, Mark F.; Mittelhauser, Glen; Mockford, Stephen; Paquet, Julie; Robertson, Gregory J.; Summers, Ron W.; Tudor, Lindsay; Mallory, Mark L. (Wiley-Blackwell, 2017-03-31)
    The Purple Sandpiper (Calidris maritima) is a medium-sized shorebird that breeds in the Arctic and winters along northern Atlantic coastlines. Migration routes and affiliations between breeding grounds and wintering grounds are incompletely understood. ...
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    Postglacial relative sea level change and glacier activity in the early and late Holocene: Wahlenbergfjorden, Nordaustlandet, Svalbard 
    Schomacker, Anders; Farnsworth, Wesley; Ingolfsson, Olafur; Allaart, Lis; Håkansson, Lena; Retelle, Michael; Siggaard-Andersen, Marie-Louise; Korsgaard, Niels Jákup; Rouillard, Alexandra; Kjellman, Sofia E. (Springer Science and Business Media LLC, 2019-05-01)
    Sediment cores from Kløverbladvatna, a threshold lake in Wahlenbergfjorden, Nordaustlandet, Svalbard were used to reconstruct Holocene glacier fluctuations. Meltwater from Etonbreen spills over a threshold to the lake, only when the glacier is significantly ...
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    Postglacial relative sea-level changes in northwest Iceland: Evidence from isolation basins, coastal lowlands and raised shorelines 
    Brader, Martin D.; Lloyd, Jeremy M.; Barlow, Natasha L.M.; Norddahl, Hreggvidur; Bentley, Michael J.; Newton, Anthony J. (Elsevier BV, 2017-08)
    Relative sea-level (RSL) data provide constraints on land uplift associated with former ice loading and can be used to differentiate between contrasting ice unloading scenarios. Isolation basin, coastal lowland and geomorphological evidence is employed ...
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    Post-Processing Approach for Refining Raw Land Cover Change Detection of Very High-Resolution Remote Sensing Images 
    Lv, Zhiyong; Liu, Tongfei; Wan, Yiliang; Benediktsson, Jon Atli; Zhang, Xiaokang (MDPI AG, 2018-03-17)
    In recent decades, land cover change detection (LCCD) using very high-spatial resolution (VHR) remote sensing images has been a major research topic. However, VHR remote sensing images usually lead to a large amount of noises in spectra, thereby reducing ...
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    Post-translational protein deimination in cod (Gadus morhua L.) ontogeny novel roles in tissue remodelling and mucosal immune defences? 
    Magnadottir, Bergljot; Hayes, Polly; Hristova, Mariya; Bragason, Birkir; Nicholas, Anthony P.; Dodds, Alister W.; Guðmundsdóttir, Sigríður; Lange, Sigrun (Elsevier BV, 2018-10)
    Peptidylarginine deiminases (PADs) are calcium dependent enzymes with physiological and pathophysiologicalroles conserved throughout phylogeny. PADs promote post-translational deimination of protein arginine to ci-trulline, altering the structure and ...
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    Potential Health Risk of Endocrine Disruptors in Construction Sector and Plastics Industry: A New Paradigm in Occupational Health 
    Fucic, Aleksandra; Galea, Karen; Duca, Radu; El Yamani, Mounia; Frery, Nadine; Godderis, Lode; Halldorsson, Thorhallur; Iavicoli, Ivo; Ndaw, Sophie; Ribeiro, Edna; Viegas, Susana; Moshammer, Hanns (MDPI AG, 2018-06-11)
    Endocrine disruptors (EDs) belong to large and diverse groups of agents that may cause multiple biological effects associated with, for example, hormone imbalance and infertility, chronic diseases such as diabetes, genome damage and cancer. The health ...
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    Pólskur og íslenskur orðaforði tvítyngdra leikskólabarna: málumhverfi heima og í leikskóla 
    Figlarska, Aneta; Oddsdóttir, Rannveig; Ragnarsdóttir, Hrafnhildur; Lefever, Samúel C. (Menntavísindasvið Háskóla Íslands, 2017-12-31)
    Máltaka tvítyngdra barna dreifist á tvö tungumál og það hversu hratt og vel þau ná tökum á málunum er meðal annars háð því ílagi sem þau fá í hvoru tungumáli fyrir sig. Rannsóknir á orðaforða tvítyngdra barna sem alast upp á Íslandi sýna að íslenskur ...
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    PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity 
    van Setten, Jessica; Brody, Jennifer A.; Jamshidi, Yalda; Swenson, Brenton R.; Butler, Anne M.; Campbell, Harry; Del Greco, Fabiola M.; Evans, Daniel S.; Gibson, Quince; Gudbjartsson, Daniel; Kerr, Kathleen F.; Krijthe, Bouwe P.; Lyytikäinen, Leo-Pekka; Müller, Christian; Müller-Nurasyid, Martina; Nolte, Ilja M.; Padmanabhan, Sandosh; Ritchie, Marylyn D.; Robino, Antonietta; Smith, Albert Vernon; Steri, Maristella; Tanaka, Toshiko; Teumer, Alexander; Trompet, Stella; Ulivi, Sheila; Verweij, Niek; Yin, Xiaoyan; Arnar, Davíð O.; Asselbergs, Folkert W.; Bader, Joel S.; Barnard, John; Bis, Josh; Blankenberg, Stefan; Boerwinkle, Eric; Bradford, Yuki; Buckley, Brendan M.; Chung, Mina K.; Crawford, Dana; den Hoed, Marcel; Denny, Josh C.; Dominiczak, Anna F.; Ehret, Georg B.; Eijgelsheim, Mark; Ellinor, Patrick T.; Felix, Stephan B.; Franco, Oscar H.; Franke, Lude; Harris, Tamara B.; Holm, Hilma; Ilaria, Gandin; Iorio, Annamaria; Kähönen, Mika; Kolcic, Ivana; Kors, Jan A.; Lakatta, Edward G.; Launer, Lenore J.; Lin, Honghuang; Lin, Henry J.; Loos, Ruth J. F.; Lubitz, Steven A.; Macfarlane, Peter W.; Magnani, Jared W.; Leach, Irene Mateo; Meitinger, Thomas; Mitchell, Braxton D.; Munzel, Thomas; Papanicolaou, George J.; Peters, Annette; Pfeufer, Arne; Pramstaller, Peter P.; Raitakari, Olli T.; Rotter, Jerome I.; Rudan, Igor; Samani, Nilesh J.; Schlessinger, David; Silva Aldana, Claudia T.; Sinner, Moritz F.; Smith, Jonathan D.; Snieder, Harold; Soliman, Elsayed Z.; Spector, Timothy D.; Stott, David J.; Strauch, Konstantin; Tarasov, Kirill V.; Þorsteinsdóttir, Unnur; Uitterlinden, Andre G.; Van Wagoner, David R.; Völker, Uwe; Völzke, Henry; Waldenberger, Melanie; Jan Westra, Harm; Wild, Philipp S.; Zeller, Tanja; Alonso, Alvaro; Avery, Christy L.; Bandinelli, Stefania; Benjamin, Emelia J.; Cucca, Francesco; Dörr, Marcus; Ferrucci, Luigi; Gasparini, Paolo; Gudnason, Vilmundur; Hayward, Caroline; Heckbert, Susan R.; Hicks, Andrew A.; Jukema, J. Wouter; Kääb, Stefan; Lehtimäki, Terho; Liu, Yongmei; Munroe, Patricia B.; Parsa, Afshin; Polasek, Ozren; Psaty, Bruce M.; Roden, Dan M.; Schnabel, Renate B.; Sinagra, Gianfranco; Stefansson, Kari; Stricker, Bruno H.; van der Harst, Pim; van Duijn, Cornelia M.; Wilson, James F.; Gharib, Sina A.; de Bakker, Paul I. W.; Isaacs, Aaron; Arking, Dan E.; Sotoodehnia, Nona (Springer Science and Business Media LLC, 2018-07-25)
    Electrocardiographic PR interval measures atrio-ventricular depolarization and conduction, and abnormal PR interval is a risk factor for atrial fibrillation and heart block. Our genome-wide association study of over 92,000 European-descent individuals ...
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    A Practical Approach for Estimating the Optimum Tilt Angle of a Photovoltaic Panel for a Long Period—Experimental Recorded Data 
    Hassanian, Reza; Riedel, Morris; Yeganeh, Nashmin; Unnthorsson, Runar (MDPI AG, 2021-11-24)
    In this study, recorded empirical data were applied with a practical approach to investigate the optimal tilt angle of the flat plate collectors facing south for a long period in Tehran, Iran. The data included 20 years of recorded average total radiation ...
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    Practising an explosive eruption in Iceland: outcomes from a European exercise 
    Witham, Claire; Barsotti, Sara; Dumont, Stéphanie; Oddsson, Björn; Sigmundsson, Freysteinn (Springer Science and Business Media LLC, 2020-01-07)
    A 3 day exercise simulating unrest and a large explosive eruption at Katla volcano, Iceland, was conducted in January 2016. A large volume of simulated data based on a complex, but realistic eruption scenario was compiled in advance and then transmitted ...
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    Predicted loss and gain of function mutations in ACO1 are associated with erythropoiesis 
    Óskarsson, Guðjón R.; Oddsson, Asmundur; Magnusson, Magnus Karl; Kristjansson, Ragnar; Halldorsson, Gisli; Ferkingstad, Egil; Zink, Florian; Helgadottir, Anna; Ívarsdóttir, Erna V.; Arnadottir, Gudny; Jensson, Brynjar Örn; Katrinardottir, Hildigunnur; Sveinbjornsson, Gardar; Kristinsdóttir, Anna Margrét; Lee, Amy L.; Sæmundsdóttir, Jóna; Stefánsdóttir, Lilja; Sigurðsson, Jón K.; Davíðsson, Ólafur B.; Benonisdottir, Stefania; Jónasdóttir, Áslaug; Jónasdóttir, Aðalbjörg; Jonsson, Stefan; Guðmundsson, Reynir L.; Asselbergs, Folkert W.; Tragante, Vinicius; Gunnarsson, Bjarni; Másson, Gísli; Thorleifsson, Gudmar; Rafnar, Thorunn; Holm, Hilma; Olafsson, Isleifur; Önundarson, Páll Torfi; Gudbjartsson, Daniel; Norðdahl, Guðmundur L.; Thorsteinsdottir, Unnur; sulem, patrick; Stefansson, Kari (Springer Science and Business Media LLC, 2020-04-23)
    Hemoglobin is the essential oxygen-carrying molecule in humans and is regulated by cellular iron and oxygen sensing mechanisms. To search for novel variants associated with hemoglobin concentration, we performed genome-wide association studies of ...
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    Preeclampsia and academic performance in children: A nationwide study from Iceland 
    Sverrisson, Friðgeir A.; Bateman, Brian T.; Aspelund, Thor; Skúlason, Sigurgrímur; Zoega, Helga (Public Library of Science (PLoS), 2018-11-21)
    Background Hypertensive disorders complicate up to 10% of pregnancies. Evidence suggests a potential association between maternal hypertensive disorders during pregnancy, particularly preeclampsia, and adverse neurodevelopment in the offspring, but ...
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    Preferred leader behaviour in the business sector of Lithuania: Follower diversity perspective 
    Minelgaite, Inga; Littrell, Romie F.; Škudienė, Vida (Vilnius University Press, 2018-12-28)
    Leadership roles in sustaining effective management have recently become paramount due to the need to keep up with the fast technical and societal developments. Moreover, business sectors in the postcommunist transformation settings are facing distinct ...
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    Preferred posture in lying and its association with scoliosis and windswept hips in adults with cerebral palsy 
    Ágústsson, Atli; Sveinsson, Thorarinn; Pope, Pauline; Rodby-Bousquet, Elisabet (Informa UK Limited, 2018-07-16)
    Objective: The aim of this study was to clarify the association of scoliosis and windswept hips with immobility, lying position, and time in lying, in adults with cerebral palsy (CP). Methods: This cross-sectional study included 830 adults (469 males ...
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    Preparative Synthesis of an RP-Guanosine-3′,5′-Cyclic Phosphorothioate Analogue, a Drug Candidate for the Treatment of Retinal Degenerations 
    Pérez, Oswaldo; Schipper, Nicolaas; Bollmark, Martin (American Chemical Society, 2021-10-19)
    Cyclic guanosine monophosphorothioate analogue 1a is currently showing potential as a drug for the treatment of inherited retinal neurodegenerations. To support ongoing preclinical and clinical work, we have developed a diastereoselective synthesis via ...
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    A Preseismic Strain Anomaly Detected Before M6 Earthquakes in the South Iceland Seismic Zone From GPS Station Velocities 
    Arnadottir, Thora; Haines, John; Geirsson, Halldor; Hreinsdóttir, Sigrún (American Geophysical Union (AGU), 2018-12)
    The South Iceland Seismic Zone (SISZ) accommodates E‐W translation due to oblique spreading between the North American and the Eurasian plates in South Iceland with ruptures on N‐S faults. Strain is released in earthquake sequences that last days to ...