Browsing Greinar- HÍ by Author "Paglia, Giuseppe"

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Elucidating dynamic metabolic physiology through network integration of quantitative time-course metabolomics

Bordbar, Aarash; Yurkovich, James T.; Paglia, Giuseppe; Rolfsson, Óttar; Sigurjónsson, Ólafur E.; Palsson, Bernhard O. (Springer Nature, 2017-04-07)

The increasing availability of metabolomics data necessitates novel methods for deeper data analysis and interpretation. We present a flux balance analysis method that allows for the computation of dynamic intracellular metabolic changes at the cellular ...
Metabolic Profiling as a Screening Tool for Cytotoxic Compounds: Identification of 3-Alkyl Pyridine Alkaloids from Sponges Collected at a Shallow Water Hydrothermal Vent Site North of Iceland

Einarsdóttir, Eydís; Magnúsdóttir, Manuela; Astarita, Giuseppe; Köck, Matthias; Ögmundsdóttir, Helga M.; Þorsteinsdóttir, Margrét; Rapp, Hans; Omarsdottir, Sesselja; Paglia, Giuseppe (MDPI AG, 2017-02-22)

Twenty-eight sponge specimens were collected at a shallow water hydrothermal vent site north of Iceland. Extracts were prepared and tested in vitro for cytotoxic activity, and eight of them were shown to be cytotoxic. A mass spectrometry (MS)-based ...

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