Háskóli Íslands: Recent submissions

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    A probabilistic geologic model of the Krafla geothermal system constrained by gravimetric data 
    Scott, Samuel; Covell, Cari; Júlíusson, Egill; Valfells, Agust; Newson, Juliet; Hrafnkelsson, Birgir; Pálsson, Halldór; Gudjónsdóttir, María (Springer Science and Business Media LLC, 2019-09-24)
    The quantitative connections between subsurface geologic structure and measured geophysical data allow 3D geologic models to be tested against measurements and geophysical anomalies to be interpreted in terms of geologic structure. Using a Bayesian ...
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    The photocurrent generated by photon replica states of an off-resonantly coupled dot-cavity system 
    Abdullah, Nzar; Tang, Chi-Shung; Manolescu, Andrei; Gudmundsson, Vidar (Springer Science and Business Media LLC, 2019-10-11)
    Transport properties of a quantum dot coupled to a photon cavity are investigated using a quantum master equation in the steady-state regime. In the off-resonance regime, when the photon energy is smaller than the energy spacing between the lowest ...
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    A CD146 FACS Protocol Enriches for Luminal Keratin 14/19 Double Positive Human Breast Progenitors 
    Ísberg, Ólöf Gerður; Kim, Jiyoung; Fridriksdottir, Agla; Morsing, Mikkel; Timmermans-Wielenga, Vera; Rønnov-Jessen, Lone; Petersen, Ole W.; Villadsen, René (Springer Science and Business Media LLC, 2019-10-16)
    Human breast cancer is believed to arise in luminal progenitors within the normal breast. A subset of these are double positive (DP) for basal and luminal keratins and localizes to a putative stem cell zone within ducts. We here present a new protocol ...
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    Attention-deficit hyperactivity disorder shares copy number variant risk with schizophrenia and autism spectrum disorder 
    Guðmundsson, Ólafur Ó.; Walters, G. Bragi; Ingason, Andrés; Johansson, Stefan; Zayats, Tetyana; Athanasiu, Lavinia; Sonderby, Ida Elken; Gústafsson, Ómar; Nawaz, Muhammad S.; Jónsson, Guðbjörn F.; Jonsson, Lina; Knappskog, Per-Morten; Ingvarsdóttir, Ester; Daviðsdóttir, Katrín; Djurovic, Srdjan; Knudsen, Gun Peggy Strømstad; Askeland, Ragna Bugge; Haraldsdóttir, Gyða S.; Baldursson, Gísli; Magnússon, Páll; Sigurdsson, Engilbert; Gudbjartsson, Daniel; Stefansson, Hreinn; Andreassen, Ole A.; Haavik, Jan; Reichborn-Kjennerud, Ted; Stefansson, Kari (Springer Science and Business Media LLC, 2019-10-17)
    Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable common childhood-onset neurodevelopmental disorder. Some rare copy number variations (CNVs) affect multiple neurodevelopmental disorders such as intellectual disability, autism ...
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    Associations of autozygosity with a broad range of human phenotypes 
    Clark, David W; Okada, Yukinori; Moore, Kristjan H S; Mason, Dan; Pirastu, Nicola; Gandin, Ilaria; Mattsson, Hannele; Barnes, Catriona L K; Lin, Kuang; Zhao, Jing Hua; Deelen, Patrick; Rohde, Rebecca; Schurmann, Claudia; Guo, Xiuqing; Giulianini, Franco; Zhang, Weihua; Medina-Gomez, Carolina; Karlsson, Robert; Bao, Yanchun; Bartz, Traci M; Baumbach, Clemens; Biino, Ginevra; Bixley, Matthew J; Brumat, Marco; Chai, Jin-Fang; Corre, Tanguy; Cousminer, Diana L; Dekker, Annelot M; Eccles, David A; van Eijk, Kristel R; Fuchsberger, Christian; Gao, He; Germain, Marine; Gordon, Scott D; de Haan, Hugoline G; Harris, Sarah E; Hofer, Edith; Huerta-Chagoya, Alicia; Igartua, Catherine; Jansen, Iris E; Jia, Yucheng; Kacprowski, Tim; Karlsson, Torgny; Kleber, Marcus E; Li, Shengchao Alfred; Li-Gao, Ruifang; Mahajan, Anubha; Matsuda, Koichi; Meidtner, Karina; Meng, Weihua; Montasser, May E; van der Most, Peter J; Munz, Matthias; Nutile, Teresa; Palviainen, Teemu; Prasad, Gauri; Prasad, Rashmi B; Priyanka, Tallapragada Divya Sri; Rizzi, Federica; Salvi, Erika; Sapkota, Bishwa R; Shriner, Daniel; Skotte, Line; Smart, Melissa C; Smith, Albert Vernon; van der Spek, Ashley; Spracklen, Cassandra N; Strawbridge, Rona J; Tajuddin, Salman M; Trompet, Stella; Turman, Constance; Verweij, Niek; Viberti, Clara; Wang, Lihua; Warren, Helen R; Wootton, Robyn E; Yanek, Lisa R; Yao, Jie; Yousri, Noha A; Zhao, Wei; Adeyemo, Adebowale A; Afaq, Saima; Aguilar-Salinas, Carlos Alberto; Akiyama, Masato; Albert, Matthew L; Allison, Matthew A; Alver, Maris; Aung, Tin; Azizi, Fereidoun; Bentley, Amy R; Boeing, Heiner; Boerwinkle, Eric; Borja, Judith B; de Borst, Gert J; Bottinger, Erwin P; Broer, Linda; Campbell, Harry; Chanock, Stephen; Chee, Miao-Li; Chen, Guanjie; Chen, Yii-Der I; Chen, Zhengming; Chiu, Yen-Feng; Cocca, Massimiliano; Collins, Francis S; Concas, Maria Pina; Corley, Janie; Cugliari, Giovanni; van Dam, Rob M; Damulina, Anna; Daneshpour, Maryam S; Day, Felix R; Delgado, Graciela E; Dhana, Klodian; Doney, Alexander S F; Dörr, Marcus; Doumatey, Ayo P; Dzimiri, Nduna; Ebenesersdóttir, Sigríður Sunna; Elliott, Joshua; Elliott, Paul; Ewert, Ralf; Felix, Janine F; Fischer, Krista; Freedman, Barry I; Girotto, Giorgia; Goel, Anuj; Gögele, Martin; Goodarzi, Mark O; Graff, Mariaelisa; Granot-Hershkovitz, Einat; Grodstein, Francine; Guarrera, Simonetta; Gudbjartsson, Daniel; Guity, Kamran; Gunnarsson, Bjarni; Guo, Yu; Hagenaars, Saskia P; Haiman, Christopher A; Halevy, Avner; Harris, Tamara B; Hedayati, Mehdi; van Heel, David A; Hirata, Makoto; Höfer, Imo; Hsiung, Chao Agnes; Huang, Jinyan; Hung, Yi-Jen; Ikram, M Arfan; Jagadeesan, Anuradha; Jousilahti, Pekka; Kamatani, Yoichiro; Kanai, Masahiro; Kerrison, Nicola D; Kessler, Thorsten; Khaw, Kay-Tee; Khor, Chiea Chuen; de Kleijn, Dominique P V; Koh, Woon-Puay; Kolcic, Ivana; Kraft, Peter; Krämer, Bernhard K; Kutalik, Zoltán; Kuusisto, Johanna; Langenberg, Claudia; Launer, Lenore J; Lawlor, Deborah A; Lee, I-Te; Lee, Wen-Jane; Lerch, Markus M; Li, Liming; Liu, Jianjun; Loh, Marie; London, Stephanie J; Loomis, Stephanie; Lu, Yingchang; Luan, Jian’an; Mägi, Reedik; Manichaikul, Ani W; Manunta, Paolo; Másson, Gísli; Matoba, Nana; Mei, Xue W; Meisinger, Christa; Meitinger, Thomas; Mezzavilla, Massimo; Milani, Lili; Millwood, Iona Y; Momozawa, Yukihide; Moore, Amy; Morange, Pierre-Emmanuel; Moreno-Macías, Hortensia; Mori, Trevor A; Morrison, Alanna C; Muka, Taulant; Murakami, Yoshinori; Murray, Alison D; de Mutsert, Renée; Mychaleckyj, Josyf C; Nalls, Mike A; Nauck, Matthias; Neville, Matt J; Nolte, Ilja M; Ong, Ken K; Orozco, Lorena; Padmanabhan, Sandosh; Pálsson, Gunnar; Pankow, James S; Pattaro, Cristian; Pattie, Alison; Polasek, Ozren; Poulter, Neil; Pramstaller, Peter P; Quintana-Murci, Lluis; Räikkönen, Katri; Ralhan, Sarju; Rao, Dabeeru C; van Rheenen, Wouter; Rich, Stephen S; Ridker, Paul M; Rietveld, Cornelius A; Robino, Antonietta; van Rooij, Frank J A; Ruggiero, Daniela; Saba, Yasaman; Sabanayagam, Charumathi; Sabater-Lleal, Maria; Sala, Cinzia Felicita; Salomaa, Veikko; Sandow, Kevin; Schmidt, Helena; Scott, Laura J; Scott, William R; Sedaghati-Khayat, Bahareh; Sennblad, Bengt; van Setten, Jessica; Sever, Peter J; Sheu, Wayne H-H; Shi, Yuan; Shrestha, Smeeta; Shukla, Sharvari Rahul; Sigurðsson, Jón K.; Sikka, Timo Tonis; Singh, Jai Rup; Smith, Blair H.; Stančáková, Alena; Stanton, Alice; Starr, John M; Stefánsdóttir, Lilja; Straker, Leon; sulem, patrick; Sveinbjornsson, Gardar; Swertz, Morris A; Taylor, Adele M; Taylor, Kent D; Terzikhan, Natalie; Tham, Yih-Chung; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Tillander, Annika; Tracy, Russell P; Tusié-Luna, Teresa; Tzoulaki, Ioanna; Vaccargiu, Simona; Vangipurapu, Jagadish; Veldink, Jan H; Vitart, Veronique; Völker, Uwe; Vuoksimaa, Eero; Wakil, Salma M; Waldenberger, Melanie; Wander, Gurpreet S; Wang, Ya Xing; Wareham, Nicholas J; Wild, Sarah; Yajnik, Chittaranjan S; Yuan, Jian-Min; Zeng, Lingyao; Zhang, Liang; Zhou, Jie; Amin, Najaf; Asselbergs, Folkert W; Bakker, Stephan J L; Becker, Diane M; Lehne, Benjamin; Bennett, David A; van den Berg, Leonard H; Berndt, Sonja I; Bharadwaj, Dwaipayan; Bielak, Lawrence F; Bochud, Murielle; Boehnke, Mike; Bouchard, Claude; Bradfield, Jonathan P; Brody, Jennifer A; Campbell, Archie; Carmi, Shai; Caulfield, Mark J; Cesarini, David; Chambers, John C; Chandak, Giriraj Ratan; Cheng, Ching-Yu; Ciullo, Marina; Cornelis, Marilyn; Cusi, Daniele; Smith, George Davey; Deary, Ian J; Dorajoo, Rajkumar; van Duijn, Cornelia M; Ellinghaus, David; Erdmann, Jeanette; Eriksson, Johan G; Evangelou, Evangelos; Evans, Michele K; Faul, Jessica D; Feenstra, Bjarke; Feitosa, Mary; Foisy, Sylvain; Franke, Andre; Friedlander, Yechiel; Gasparini, Paolo; Gieger, Christian; Gonzalez, Clicerio; Goyette, Philippe; Grant, Struan F A; Griffiths, Lyn R; Groop, Leif; Gudnason, Vilmundur; Gyllensten, Ulf; Hakonarson, Hakon; Hamsten, Anders; van der Harst, Pim; Heng, Chew-Kiat; Hicks, Andrew A; Hochner, Hagit; Huikuri, Heikki; Hunt, Steven C; Jaddoe, Vincent W V; De Jager, Philip L; Johannesson, Magnus; Johansson, Åsa; Jonas, Jost B; Jukema, J. Wouter; Junttila, Juhani; Kaprio, Jaakko; Kardia, Sharon L. R.; Karpe, Fredrik; Kumari, Meena; Laakso, Markku; van der Laan, Sander W; Lahti, Jari; Laudes, Matthias; Lea, Rodney A; Lieb, Wolfgang; Lumley, Thomas; Martin, Nicholas G; März, Winfried; Matullo, Giuseppe; McCarthy, Mark I; Medland, Sarah E; Merriman, Tony R; Metspalu, Andres; Meyer, Brian F; Mohlke, Karen L; Montgomery, Grant W; Mook-Kanamori, Dennis; Munroe, Patricia B; North, Kari E; Nyholt, Dale R; O’connell, Jeffery R; Ober, Carole; Oldehinkel, Albertine J; Palmas, Walter; Palmer, Colin; Pasterkamp, Gerard G; Patin, Etienne; Pennell, Craig E; Perusse, Louis; Peyser, Patricia A; Pirastu, Mario; Polderman, Tinca J. C.; Porteous, David J; Posthuma, Danielle; Psaty, Bruce M; Rioux, John D; Rivadeneira, Fernando; Rotimi, Charles; Rotter, Jerome I; Rudan, Igor; Den Ruijter, Hester M; Sanghera, Dharambir K; Sattar, Naveed; Schmidt, Reinhold; Schulze, Matthias B; Schunkert, Heribert; Scott, Robert A; Shuldiner, Alan R; Sim, Xueling; Small, Neil; Smith, Jennifer A; Sotoodehnia, Nona; Tai, E-Shyong; Teumer, Alexander; Timpson, Nicholas J; Toniolo, Daniela; Tregouet, David-Alexandre; Tuomi, Tiinamaija; Vollenweider, Peter; Wang, Carol A; Weir, David R; Whitfield, John B; Wijmenga, Cisca; Wong, Tien-Yin; Wright, John; Yang, Jingyun; Yu, Lei; Zemel, Babette S; Zonderman, Alan B; Perola, Markus; Magnusson, Patrik K. E.; Uitterlinden, André G; Kooner, Jaspal S; Chasman, Daniel I; Loos, Ruth J. F.; Franceschini, Nora; Franke, Lude; Haley, Chris S; Hayward, Caroline; Walters, Robin G; Perry, John R. B.; Esko, Tōnu; Helgason, Agnar; Stefansson, Kari; Joshi, Peter K; Kubo, Michiaki; Wilson, James F (Springer Science and Business Media LLC, 2019-10-31)
    In many species, the offspring of related parents suffer reduced reproductive success, a phenomenon known as inbreeding depression. In humans, the importance of this effect has remained unclear, partly because reproduction between close relatives is ...
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    Non-equilibrium steady states in quantum critical systems with Lifshitz scaling 
    Fernández, Daniel; Rajagopal, Aruna; Thorlacius, Larus (Springer Science and Business Media LLC, 2019-12-01)
    We study out-of-equilibrium energy transport in a quantum critical fluid with Lifshitz scaling symmetry following a local quench between two semi-infinite fluid reservoirs. The late time energy flow is universal and is accommodated via a steady state ...
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    Stability and lifetime of antiferromagnetic skyrmions 
    Bessarab, Pavel; Yudin, D.; Gulevich, D. R.; Wadley, P.; Titov, M.; Tretiakov, Oleg A. (American Physical Society (APS), 2019-04-26)
    The two-dimensional Heisenberg exchange model with out-of-plane anisotropy and a Dzyaloshinskii-Moriya interaction is employed to investigate the lifetime and stability of antiferromagnetic (AFM) skyrmion as a function of temperature and external ...
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    Sequence variants with large effects on cardiac electrophysiology and disease 
    Norland, Kristján; Sveinbjornsson, Gardar; Thorolfsdottir, Rosa B; Davidsson, Olafur B.; Tragante, Vinicius; Rajamani, Sridharan; Helgadottir, Anna; Grétarsdóttir, Sólveig; van Setten, Jessica; Asselbergs, Folkert W.; Sverrisson, Jon Th.; Stephensen, Sigurdur Sverrir; Óskarsson, Gylfi; Sigurðsson, Emil Lárus; Andersen, Karl; Danielsen, Ragnar; Thorgeirsson, Gudmundur; Thorsteinsdottir, Unnur; Arnar, Davíð O.; sulem, patrick; Holm, Hilma; Gudbjartsson, Daniel; Stefansson, Kari (Springer Science and Business Media LLC, 2019-10-22)
    Features of the QRS complex of the electrocardiogram, reflecting ventricular depolarisation, associate with various physiologic functions and several pathologic conditions. We test 32.5 million variants for association with ten measures of the QRS ...
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    The microphthalmia-associated transcription factor (Mitf) gene and its role in regulating eye function 
    García-Llorca, Andrea; Gudmundsdottir Aspelund, Snaefridur; Ogmundsdottir, Margret H; Steingrimsson, Eirikur; Eysteinsson, Thor (Springer Science and Business Media LLC, 2019-10-28)
    Mutations in the microphthalmia-associated transcription factor (Mitf) gene can cause retinal pigment epithelium (RPE) and retinal dysfunction and degeneration. We examined retinal and RPE structure and function in 3 month old mice homo- or heterozygous ...
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    Interim Results from the IMPACT Study: Evidence for Prostate-specific Antigen Screening in BRCA2 Mutation Carriers 
    Page, Elizabeth C.; Bancroft, Elizabeth K.; Brook, Mark N.; Assel, Melissa; Hassan Al Battat, Mona; Thomas, Sarah; Taylor, Natalie; Chamberlain, Anthony; Pope, Jennifer; Raghallaigh, Holly Ni; Evans, D. Gareth; Rothwell, Jeanette; Maehle, Lovise; Grindedal, Eli Marie; James, Paul; Mascarenhas, Lyon; McKinley, Joanne; Side, Lucy; Thomas, Tessy; van Asperen, Christi; Vasen, Hans; Kiemeney, Lambertus A.; Ringelberg, Janneke; Jensen, Thomas Dyrsø; Osther, Palle J.S.; Helfand, Brian T.; Genova, Elena; Oldenburg, Rogier A.; Cybulski, Cezary; Wokolorczyk, Dominika; Ong, Kai-Ren; Huber, Camilla; Lam, Jimmy; Taylor, Louise; Salinas, Monica; Feliubadaló, Lidia; Oosterwijk, Jan C.; van Zelst-Stams, Wendy; Cook, Jackie; Rosario, Derek J.; Domchek, Susan; Powers, Jacquelyn; Buys, Saundra; O'Toole, Karen; Ausems, Margreet G.E.M.; Schmutzler, Rita K.; Rhiem, Kerstin; Izatt, Louise; Tripathi, Vishakha; Teixeira, Manuel R.; Cardoso, Marta; Foulkes, William D.; Aprikian, Armen; van Randeraad, Heleen; Davidson, Rosemarie; Longmuir, Mark; Ruijs, Mariëlle W.G.; Helderman van den Enden, Apollonia T.J.M.; Adank, Muriel; Williams, Rachel; Andrews, Lesley; Murphy, Declan G.; Halliday, Dorothy; Walker, Lisa; Liljegren, Annelie; Carlsson, Stefan; Azzabi, Ashraf; Jobson, Irene; Morton, Catherine; Shackleton, Kylie; Snape, Katie; Hanson, Helen; Harris, Marion; Tischkowitz, Marc; Taylor, Amy; Kirk, Judy; Susman, Rachel; Chen-Shtoyerman, Rakefet; Spigelman, Allan; Pachter, Nicholas; Ahmed, Munaza; Ramon y Cajal, Teresa; Zgajnar, Janez; Brewer, Carole; Gadea, Neus; Brady, Angela F.; van Os, Theo; Gallagher, David; Johannsson, Oskar; Donaldson, Alan; Barwell, Julian; Nicolai, Nicola; Friedman, Eitan; Obeid, Elias; Greenhalgh, Lynn; Murthy, Vedang; Copakova, Lucia; Saya, Sibel; McGrath, John; Cooke, Peter; Rønlund, Karina; Richardson, Kate; Henderson, Alex; Teo, Soo H.; Arun, Banu; Kast, Karin; Dias, Alexander; Aaronson, Neil K.; Ardern-Jones, Audrey; Bangma, Chris H.; Castro, Elena; Dearnaley, David; Eccles, Diana M.; Tricker, Karen; Eyfjörð, Jórunn Erla; Falconer, Alison; Foster, Christopher; Gronberg, Henrik; Hamdy, Freddie C.; Stefansdottir, Vigdis; Khoo, Vincent; Lindeman, Geoffrey J.; Lubinski, Jan; Axcrona, Karol; Mikropoulos, Christos; Mitra, Anita; Moynihan, Clare; Rennert, Gadi; Suri, Mohnish; Wilson, Penny; Dudderidge, Tim; Offman, Judith; Kote-Jarai, Zsofia; Vickers, Andrew; Lilja, Hans; Eeles, Rosalind A. (Elsevier BV, 2019-12)
    Background: Mutations in BRCA2 cause a higher risk of early-onset aggressive prostate cancer (PrCa). The IMPACT study is evaluating targeted PrCa screening using prostate-specific-antigen (PSA) in men with germline BRCA1/2 mutations. Objective: To ...
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    Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration 
    Noordam, Raymond; Bos, Maxime M.; Wang, Heming; Winkler, Thomas W.; Bentley, Amy R.; Kilpeläinen, Tuomas O.; de Vries, Paul S.; Sung, Yun Ju; Schwander, Karen; Cade, Brian E.; Manning, Alisa; Aschard, Hugues; Brown, Michael R.; Chen, Han; Franceschini, Nora; Musani, Solomon K.; Richard, Melissa; Vojinovic, Dina; Aslibekyan, Stella; Bartz, Traci M.; de las Fuentes, Lisa; Feitosa, Mary; Horimoto, Andrea R.; Ilkov, Marjan; Kho, Minjung; Kraja, Aldi; Li, Changwei; Lim, Elise; Liu, Yongmei; Mook-Kanamori, Dennis O.; Rankinen, Tuomo; Tajuddin, Salman M.; van der Spek, Ashley; Wang, Zhe; Marten, Jonathan; Laville, Vincent; Alver, Maris; Evangelou, Evangelos; Graff, Maria E.; He, Meian; Kühnel, Brigitte; Lyytikäinen, Leo-Pekka; Marques-Vidal, Pedro; Nolte, Ilja M.; Palmer, Nicholette D.; Rauramaa, Rainer; Shu, Xiao-Ou; Snieder, Harold; Weiss, Stefan; Wen, Wanqing; Yanek, Lisa R.; Adolfo, Correa; Ballantyne, Christie; Bielak, Larry; Biermasz, Nienke R.; Boerwinkle, Eric; Dimou, Niki; Eiriksdottir, Gudny; Gao, Chuan; Gharib, Sina A.; Gottlieb, Daniel J.; Haba-Rubio, José; Harris, Tamara B.; Heikkinen, Sami; Heinzer, Raphaël; Hixson, James E.; Homuth, Georg; Ikram, M. Arfan; Komulainen, Pirjo; Krieger, Jose E.; Lee, Jiwon; Liu, Jingmin; Lohman, Kurt K.; Luik, Annemarie I.; Mägi, Reedik; Martin, Lisa W.; Meitinger, Thomas; Metspalu, Andres; Milaneschi, Yuri; Nalls, Mike A.; O’Connell, Jeff; Peters, Annette; Peyser, Patricia; Raitakari, Olli T.; Reiner, Alex P.; Rensen, Patrick C. N.; Rice, Treva K.; Rich, Stephen S.; Roenneberg, Till; Rotter, Jerome I.; Schreiner, Pamela J.; Shikany, James; Sidney, Stephen S.; Sims, Mario; Sitlani, Colleen M.; Sofer, Tamar; Strauch, Konstantin; Swertz, Morris A.; Taylor, Kent D.; Uitterlinden, André G.; van Duijn, Cornelia M.; Völzke, Henry; Waldenberger, Melanie; Wallance, Robert B.; van Dijk, Ko Willems; Yu, Caizheng; Zonderman, Alan B.; Becker, Diane M.; Elliott, Paul; Esko, Tõnu; Gieger, Christian; Grabe, Hans J.; Lakka, Timo A.; Lehtimäki, Terho; North, Kari E.; Penninx, Brenda W. J. H.; Vollenweider, Peter; Wagenknecht, Lynne E.; Wu, Tangchun; Xiang, Yong-Bing; Zheng, Wei; Arnett, Donna K.; Bouchard, Claude; Evans, Michele K.; Gudnason, Vilmundur; Kardia, Sharon; Kelly, Tanika N.; Kritchevsky, Stephen B.; Loos, Ruth J. F.; Pereira, Alexandre C.; Province, Mike; Psaty, Bruce M.; Rotimi, Charles; Zhu, Xiaofeng; Amin, Najaf; Cupples, L. Adrienne; Fornage, Myriam; Fox, Ervin F.; Guo, Xiuqing; Gauderman, W. James; Rice, Kenneth; Kooperberg, Charles; Munroe, Patricia B.; Liu, Ching-Ti; Morrison, Alanna C.; Rao, Dabeeru C.; van Heemst, Diana; Redline, Susan (Springer Science and Business Media LLC, 2019-11-12)
    Both short and long sleep are associated with an adverse lipid profile, likely through different biological pathways. To elucidate the biology of sleep-associated adverse lipid profile, we conduct multi-ancestry genome-wide sleep-SNP interaction analyses ...
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    On the long-term sustainability of copper, zinc and lead supply, using a system dynamics model 
    Sverdrup, Harald Ulrik; Olafsdottir, Anna; Ragnarsdottir, Kristin Vala (Elsevier BV, 2019-12)
    The long-term supply sustainability of copper, zinc and lead was assessed. Copper will not run into physcal scarcity in the future, but increased demand and decreased resource quality will cause significant price increases. The copper price is suggested ...
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    Formation of segregation structures in Hafnarhraun pāhoehoe lobe, SW Iceland: a window into crystal–melt separation in basaltic magma 
    Nikkola, Paavo; Thordarson, Thorvaldur; Rämö, O. Tapani; Heikkilä, Pasi (Springer Science and Business Media LLC, 2019-11-25)
    To gain insights into crystal–melt separation processes during basalt differentiation, we have studied an 8-m-thick pāhoehoe lava lobe from the Hafnarhraun lava flow field in SW Iceland. The lobe has abundant melt segregations, porous cylindrical and ...
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    GraphTyper2 enables population-scale genotyping of structural variation using pangenome graphs 
    Eggertsson, Hannes; Kristmundsdóttir, Snædís; Beyter, Doruk; Jónsson, Hákon; Skúladóttir, Ástrós; Hardarson, Marteinn; Gudbjartsson, Daniel; Stefansson, Kari; Halldórsson, Bjarni; Melsted, Páll (Springer Science and Business Media LLC, 2019-11-27)
    Analysis of sequence diversity in the human genome is fundamental for genetic studies. Structural variants (SVs) are frequently omitted in sequence analysis studies, although each has a relatively large impact on the genome. Here, we present GraphTyper2, ...
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    Brain age prediction using deep learning uncovers associated sequence variants 
    Jónsson, Benedikt Atli; Bjornsdottir, Gyda; Thorgeirsson, Thorgeir; Ellingsen, Lotta María; Walters, G. Bragi; Gudbjartsson, Daniel; Stefansson, Hreinn; Stefansson, Kari; Ulfarsson, Magnus (Springer Science and Business Media LLC, 2019-11-27)
    Machine learning algorithms can be trained to estimate age from brain structural MRI. The difference between an individual’s predicted and chronological age, predicted age difference (PAD), is a phenotype of relevance to aging and brain disease. Here, ...
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    An Isocaloric Nordic Diet Modulates RELA and TNFRSF1A Gene Expression in Peripheral Blood Mononuclear Cells in Individuals with Metabolic Syndrome—A SYSDIET Sub-Study 
    Ulven, Stine M.; Holven, Kirsten B.; Rundblad, Amanda; Myhrstad, Mari C. W.; Leder, Lena; Dahlman, Ingrid; Mello, Vanessa D. de; Schwab, Ursula; Carlberg, Carsten; Pihlajamäki, Jussi; Hermansen, Kjeld; Dragsted, Lars O.; Gunnarsdottir, Ingibjorg; Cloetens, Lieselotte; Åkesson, Björn; Rosqvist, Fredrik; Hukkanen, Janne; Herzig, Karl-Heinz; Savolainen, Markku J; Risérus, Ulf; Thorsdottir , Inga; Poutanen, Kaisa S; Arner, Peter; Uusitupa, Matti; Kolehmainen, Marjukka (MDPI AG, 2019-12-03)
    A healthy dietary pattern is associated with a lower risk of metabolic syndrome (MetS) and reduced inflammation. To explore this at the molecular level, we investigated the effect of a Nordic diet (ND) on changes in the gene expression profiles of ...
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    Disappearance of Icelandic Walruses Coincided with Norse Settlement 
    Keighley, Xénia; Palsson, Snaebjorn; Einarsson, Bjarni F; Petersen, Ævar; Fernández-Coll, Meritxell; Jordan, Peter; Olsen, Morten Tange; Malmquist, Hilmar (Oxford University Press (OUP), 2019-09-12)
    There is a growing body of evidence demonstrating the impacts of human arrival in new “pristine” environments, including terrestrial habitat alterations and species extinctions. However, the effects of marine resource utilization prior to industrialized ...
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    Doxycycline and Monocaprin In Situ Hydrogel: Effect on Stability, Mucoadhesion and Texture Analysis and In Vitro Release 
    Patlolla, Venu Gopal Reddy; Peter Holbrook, William; Gizurarson, Sveinbjorn; Kristmundsdóttir, Thórdís (MDPI AG, 2019-12-09)
    The aim of this study was to develop a stable aqueous formulation containing a combination of doxycycline and monocaprin in clinically relevant concentrations. Increase in expression of Matrix metalloproteinases (MMPs) and microbial role in oral ...
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    Serial dependence in a simulated clinical visual search task 
    Manassi, Mauro; Kristjansson, Arni; Whitney, David (Springer Science and Business Media LLC, 2019-12-01)
    In everyday life, we continuously search for and classify objects in the environment around us. This kind of visual search is extremely important when performed by radiologists in cancer image interpretation and officers in airport security screening. ...
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    Combined artificial high-silicate medium and LED illumination promote carotenoid accumulation in the marine diatom Phaeodactylum tricornutum 
    Yi, Zhiqian; Su, Yixi; Cherek, Paulina; Nelson, David R.; Lin, Jianping; Rolfsson, Óttar; Wu, Hua; Salehi-Ashtiani, Kourosh; Brynjolfsson, Sigurdur; Fu, Weiqi (Springer Science and Business Media LLC, 2019-12-02)
    Background: Diatoms, which can accumulate large amounts of carotenoids, are a major group of microalgae and the dominant primary producer in marine environments. Phaeodactylum tricornutum, a model diatom species, acquires little silicon for its growth ...