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The Lair: a resource for exploratory analysis of published RNA-Seq data

The Lair: a resource for exploratory analysis of published RNA-Seq data

Title: The Lair: a resource for exploratory analysis of published RNA-Seq data
Author: Pimentel, Harold
Sturmfels, Pascal
Bray, Nicolas
Melsted, Páll   orcid.org/0000-0002-8418-6724
Pachter, Lior
Date: 2016-12
Language: English
Scope: 490
University/Institute: Háskóli Íslands
University of Iceland
School: Verkfræði- og náttúruvísindasvið (HÍ)
School of Engineering and Natural Sciences (UI)
Department: Iðnaðarverkfræði-, vélaverkfræði- og tölvunarfræðideild (HÍ)
Faculty of Industrial Eng., Mechanical Eng. and Computer Science (UI)
Series: BMC Bioinformatics;17(1)
ISSN: 1471-2105
DOI: 10.1186/s12859-016-1357-2
Subject: RNA-Seq.; Sequence read archive; Exploratory data analysis; RNA kjarnsýra; Gagnagrunnar
URI: https://hdl.handle.net/20.500.11815/386

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Citation:

Pimentel, H., Sturmfels, P., Bray, N., Melsted, P., & Pachter, L. (2016). The Lair: a resource for exploratory analysis of published RNA-Seq data. BMC Bioinformatics, 17(1), 490. doi:10.1186/s12859-016-1357-2

Abstract:

Increased emphasis on reproducibility of published research in the last few years has led to the large-scale archiving of sequencing data. While this data can, in theory, be used to reproduce results in papers, it is difficult to use in practice. We introduce a series of tools for processing and analyzing RNA-Seq data in the Sequence Read Archive, that together have allowed us to build an easily extendable resource for analysis of data underlying published papers. Our system makes the exploration of data easily accessible and usable without technical expertise. Our database and associated tools can be accessed at The Lair: http://pachterlab.github.io/lair.

Rights:

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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