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IRIS
IRIS
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(2023-12-20)OBJECTIVES: This study aims to examine whether comorbidities affect the likelihood of reaching primary remission on methotrexate monotherapy as the first disease-modifying antirheumatic drug (DMARD) in early rheumatoid arthritis (RA). METHODS: We used ... -
(2023-11-03)Background/Aims: The goal of health research is to improve patients care and outcomes. Thus, it is essential that research addresses questions that are important to patients and clinicians. The aim of this study was to develop a list of priorities for ...
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(2023-11-02)AIMS: Atrial fibrillation (AF) is associated with high risk of comorbidities and mortality. Our aim was to examine causal and predictive relationships between 4137 serum proteins and incident AF in the prospective population-based Age, Gene/Environment ...
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(2023-04-27)The scale of post-transcriptional regulation and the implications of its interplay with other forms of regulation in environmental acclimation are underexplored for organisms of the domain Archaea. Here, we have investigated the scale of post-transcriptional ...
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(2023-08-02)We investigated the associations of plasma neurofilament light (NfL), glial fibrillary acidic protein (GFAP), and total tau (t-tau) with markers of cerebral small vessel disease (SVD) and with incident dementia. We also investigated whether associations ...
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(2024-01-01)In plant science, it is an established method to obtain structural parameters of crops using image analysis. In recent years, deep learning techniques have improved the underlying processes significantly. However, since data acquisition is time and ...
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(2024-01)The asymmetric synthesis of polyunsaturated triene C18:3 n-3 and C18:3 n-6 methoxylated ether lipids (MEL) of the 1-O-alkyl-sn-glycerol type is described as possible structural candidates for a triene C18:3 MEL of an unknown identity found in a mixture ...
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(2024)In the original publication of the article, under the section “Conclusion”, the citation information was incorrectly given as “see also Bååth, 2022a” but it should have been “see also Bååth, 2018; 2022b”. The original article was updated.
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(Utrecht University - Freudenthal Institute, 2019)The paper describes two Icelandic arithmetic textbooks, published respectively in 1780 and 1911– 14, both written at the beginning of an era when enhancing general education was placed on the agenda for restoring the Icelandic society after natural ...
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(2024-03)Background: The short- and long-term consequences of restricted fetal growth cause considerable concern, and how prenatal exposure to different antiseizure medications (ASMs) affects fetal growth remains uncertain. Methods: This was a population-based ...
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(2024-02-26)Importance: Use of valproate and certain other antiseizure medications (ASMs) in pregnancy is associated with abnormal fetal brain development with potential long-term implications for the child. Objective: To examine whether use of valproate and other ...
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(2024-02)Background: Nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease in the world. Common comorbidities are central obesity, type 2 diabetes mellitus, dyslipidemia, and metabolic syndrome. Cardiovascular disease is the ...
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(2024)Aims: To estimate the changes in intraocular pressure (IOP) during the first 24 h after transscleral cyclophotocoagulation (TCP). Methods: A prospective single-centre study, where patients with glaucoma destined for treatment with TCP were asked for ...
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(2024-02-20)Psoriatic arthritis mutilans (PAM) is the rarest and most severe form of psoriatic arthritis, characterized by erosions of the small joints and osteolysis leading to joint disruption. Despite its severity, the underlying mechanisms are unknown, and no ...
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(2024-01-09)Primary open-angle glaucoma (POAG), characterized by retinal ganglion cell death, is a leading cause of irreversible blindness worldwide. However, its molecular and cellular causes are not well understood. Elevated intraocular pressure (IOP) is a major ...
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(2024-01)This study introduces a systems-theoretic methodology to meet the requirements of a major national infrastructure for safety and security-based design by enhancing the alignment of stakeholders and actors in the project. Safe-by-Design (SbD) is an ...
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(2024)The mixed evidence of the association between high levels of cardiovascular risk factors (CVRF) and the risk for cognitive impairment may be due to confounding of age across studies. We pooled and harmonized individual-level data (30,967 persons, age ...
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(2024-06)This paper explores the potential of large language models, specifically ChatGPT, to reframe problems from probability theory and statistics, making them accessible to students across diverse academic fields including biology, economics, law, and ...