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Browsing by Subject "Risk Factors"

Browsing by Subject "Risk Factors"

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  • Daníelsdóttir, Hilda Björk; Aspelund, Thor; Thordardottir, Edda Bjork; Fall, Katja; Fang, Fang; Tómasson, Gunnar; Rúnarsdóttir, Harpa; Yang, Qian; Choi, Karmel W; Kennedy, Beatrice; Halldorsdottir, Thorhildur; Lu, Donghao; Song, Huan; Jakobsdóttir, Jóhanna; Hauksdóttir, Arna; Valdimarsdóttir, Unnur Anna (2022-02-01)
    Background: Adverse childhood experiences (ACEs) have consistently been associated with elevated risk of multiple adverse health outcomes, yet their contribution to coping ability and psychiatric resilience in adulthood is unclear. Methods: Cross-sectional ...
  • Petursdottir, Astridur; Gunnarsson, Örvar; Valsdóttir, Elsa Björk (2020-07)
    INNGANGUR Krabbameinager í kviðarholi er oft afleiðing krabbameins í ristli eða endaþarmi og er illlæknanlegt ástand. Lifun sjúklinga með krabbameinager hefur að meðaltali verið undir tveimur árum eftir kerfislæga krabbameinslyfjameðferð með eða án ...
  • Bergmann, Asa Unnur; Þórkelsson, Þórður (2020-03-04)
    INNGANGUR Nýburagula orsakast af auknu magni gallrauða í vefjum og blóði nýbura fyrstu dagana eftir fæðingu. Yfirleitt þarf ekki að meðhöndla nýburagulu en ef styrkur gallrauða í blóði verður of mikill getur hann valdið langvarandi heilaskaða. Vegna ...
  • Vilaplana-Pérez, Alba; Sidorchuk, Anna; Pérez-Vigil, Ana; Brander, Gustaf; Isoumura, Kayoko; Hesselmark, Eva; Sevilla-Cermeño, Laura; Valdimarsdóttir, Unnur Anna; Song, Huan; Jangmo, Andreas; Kuja-Halkola, Ralf; D'Onofrio, Brian M.; Larsson, Henrik; Garcia-Soriano, Gemma; Mataix-Cols, David; Fernández de la Cruz, Lorena (2020-12-01)
    Importance: Posttraumatic stress disorder (PTSD) has been associated with impaired educational performance. Previous studies on the disorder could not control for important measured and unmeasured confounders. Objective: To prospectively investigate ...
  • Li, Yuchen; Sjölander, Arvid; Song, Huan; Cnattingius, Sven; Fang, Fang; Yang, Qian; Fernández de la Cruz, Lorena; Mataix-Cols, David; Brander, Gustaf; Li, Jiong; Zhang, Wei; Fall, Katja; D’Onofrio, Brian M.; Almqvist, Catarina; Lichtenstein, Paul; Valdimarsdóttir, Unnur Anna; Lu, Donghao (2022-01-01)
    Little is known about the contribution of pregnancy-related parental and perinatal factors to the development of stress-related disorders. We aimed to investigate whether parental/perinatal adversities entail higher risks of stress-related disorders ...
  • Wang, Juan; Janson, Christer; Malinovschi, Andrei; Holm, Mathias; Franklin, Karl A.; Modig, Lars; Johannessen, Ane; Schlünssen, Vivi; Gíslason, Þórarinn; Jogi, Nils Oskar; Norbäck, Dan (2022-12-01)
    We studied home environment exposures in relation to asthma, allergic rhinitis and atopic dermatitis among offspring of participants (parents) in the Respiratory Health in Northern Europe (RHINE) study (age ≤ 30 y). Totally 17,881 offspring from Iceland, ...
  • Lárusdóttir, Katrín Júniána; Guðmundsson, Hjalti J.; Johnsen, Árni; Sigurðsson, Martin Ingi; Guðbjartsson, Tómas; Guomundsdóttir, Ingibjörg Jóna (2021-03)
    INNGANGUR Ósæðarlokuþrengsl eru algengasti lokusjúkdómurinn á Vesturlöndum. Hefðbundin meðferð við alvarlegum þrengslum hefur verið opin ósæðarlokuskipti en síðastliðin ár hefur ósæðarlokuísetning með þræðingartækni (TAVI) rutt sér til rúms hér á landi ...
  • Axelsson, Gísli Þór; Eyþórsson, Elías Sæbjörn; Harðardóttir, Hrönn; Guðmundsson, Gunnar; Hansdóttir, Sif (2020-12)
    INNGANGUR Heimsfaraldur COVID-19-sjúkdóms af völdum SARS-CoV-2 hefur valdið miklu álagi á heilbrigðiskerfi um allan heim og aðgerðir vegna hans valdið miklu efnahagstjóni. Alvarlegum sjúkdómi fylgir yfirleitt lungnabólga og fylgikvillar frá lungum eru ...
  • Andersen, Karl Konráð; Aspelund, Thor; Gudmundsson, Elias Freyr; Sigurdsson, Gunnar; Sigurdsson, Sigurdur; Björnsdóttir, Guðlaug; Thorsson, Bolli; Sigurdsson, Gunnar; Hardarsson, Thordur; Gudnason, Vilmundur (2022-07-07)
    INNGANGUR Lágt menntunarstig hefur verið tengt óhagstæðri samsetningu áhættuþátta kransæðasjúkdóma. Þessu fylgir aukin áhætta á hjartaáföllum hjá minna menntuðum. Litlar upplýsingar eru til um samband menntunarstigs við alvarleika æðakölkunarsjúkdóma. ...
  • Gautadottir, Kolfinna; Guðmundsdóttir, Ingibjörg Jóna; Sigurðsson, Martin Ingi; Andersen, Karl Konráð (2022-10-04)
    INNGANGUR Nýgengi bráðs hjartadreps hefur lækkað í almennu þýði á undanförnum áratugum en margt bendir til þess að þetta eigi ekki við um yngstu aldurshópana. Markmið þessarar rannsóknar var að kanna nýgengi, áhættuþætti og horfur eftir brátt hjartadrep ...
  • GEMO Study Collaborators; EMBRACE Collaborators; kConFab Investigators; HEBON Investigators; Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (2022-01)
    BACKGROUND: Recent population-based female breast cancer and prostate cancer polygenic risk scores (PRS) have been developed. We assessed the associations of these PRS with breast and prostate cancer risks for male BRCA1 and BRCA2 pathogenic variant ...
  • Halldórsson, Arnljótur Björn; Axelsson, Gísli Þór; Jónsson, Helgi; Ísaksson, Jóhann Davíð; Harðardóttir, Hrönn; Guðmundsson, Gunnar; Hansdóttir, Sif (2021-10)
    Introduction Infections due to COVID-19 can lead to life threatening pneumonia. Accompanying severe disease are more prominent pulmonary changes on Computed Tomography (CT) scan of the chest. The goal of this study was to describe pulmonary CT changes ...
  • Wang, Junren; Zhu, Jianwei; Yang, Huazhen; Hu, Yao; Sun, Yajing; Ying, Zhiye; Qu, Yuanyuan; Valdimarsdottir, Unnur; Fang, Fang; Song, Huan (2021-06-04)
    Objective To assess the impact of the COVID-19 outbreak on cardiovascular disease (CVD) related mortality and hospitalisation. Design Community-based prospective cohort study. Setting The UK Biobank. Participants 421 372 UK Biobank participants who ...
  • DBDS Genomic Consortium (2022-12-21)
    BACKGROUND AND AIMS: The causal contribution of apolipoprotein B (apoB) particles to coronary artery disease (CAD) is established. We examined whether this atherogenic contribution is better reflected by non-high-density lipoprotein cholesterol (non-HDL-C) ...
  • Rezk, Mary; Taha, Amar; Nielsen, Susanne J.; Gudbjartsson, Tomas; Bergfeldt, Lennart; Ahlsson, Anders; Jeppsson, Anders (2022-12-01)
    BACKGROUND: New-onset postoperative atrial fibrillation (POAF) after cardiac surgery is associated with worse short- and long-term outcomes. Although the clinical presentation of POAF varies substantially, almost all studies model it with a dichotomous ...
  • Yang, Qian; Sjölander, Arvid; Li, Yuchen; Viktorin, Alexander; Bertone-Johnson, Elizabeth R.; Ye, Weimin; Fang, Fang; Valdimarsdóttir, Unnur A.; Lu, Donghao (2021-05-26)
    Background: Premenstrual disorders, including premenstrual syndrome and premenstrual dysphoric disorder, are suggested to be correlated with suicidal behavior and accidents in cross-sectional and retrospective studies. However, prospective data are ...
  • Eloranta, Aino Maija; Gunnarsdottir, Ingibjörg; Thorisdottir, Birna; Gunnlaugsson, Geir; Birgisdottir, Bryndis Eva; Thorsdottir, Inga; Einarsdóttir, Kristjana (2023-01-05)
    Women who are obese before pregnancy have a higher risk of caesarean section than normal weight women. We investigated the combined effect of pre-pregnancy weight and gestational weight gain on pre-labour and intrapartum caesarean section risk. We ...
  • Hu, Yihan; Yang, Huazhen; Hou, Can; Chen, Wenwen; Zhang, Hanyue; Ying, Zhiye; Hu, Yao; Sun, Yajing; Qu, Yuanyuan; Feychting, Maria; Valdimarsdóttir, Unnur Anna; Song, Huan; Fang, Fang (2022-01-07)
    Background: An increased susceptibility to COVID-19 has been suggested for individuals with neurodegenerative diseases, but data are scarce from longitudinal studies. Methods: In this community-based cohort study, we included 96,275 participants of the ...
  • Vonk, Jet M.J.; Greving, Jacoba P.; Gudnason, Vilmundur; Launer, Lenore J.; Geerlings, Mirjam I. (2021-07-25)
    We aimed to evaluate the external performance of prediction models for all-cause dementia or AD in the general population, which can aid selection of high-risk individuals for clinical trials and prevention. We identified 17 out of 36 eligible published ...
  • Regeneron Genetics Center (2023-06-01)
    AIMS: Although highly heritable, the genetic etiology of calcific aortic stenosis (AS) remains incompletely understood. The aim of this study was to discover novel genetic contributors to AS and to integrate functional, expression, and cross-phenotype ...