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Browsing by Subject "Risk Factors"

Browsing by Subject "Risk Factors"

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  • Daníelsdóttir, Hilda Björk; Aspelund, Thor; Thordardottir, Edda Bjork; Fall, Katja; Fang, Fang; Tómasson, Gunnar; Rúnarsdóttir, Harpa; Yang, Qian; Choi, Karmel W; Kennedy, Beatrice; Halldorsdottir, Thorhildur; Lu, Donghao; Song, Huan; Jakobsdóttir, Jóhanna; Hauksdóttir, Arna; Valdimarsdóttir, Unnur Anna (2022-02-01)
    Background: Adverse childhood experiences (ACEs) have consistently been associated with elevated risk of multiple adverse health outcomes, yet their contribution to coping ability and psychiatric resilience in adulthood is unclear. Methods: Cross-sectional ...
  • Petursdottir, Astridur; Gunnarsson, Örvar; Valsdóttir, Elsa Björk (2020-07)
    INNGANGUR Krabbameinager í kviðarholi er oft afleiðing krabbameins í ristli eða endaþarmi og er illlæknanlegt ástand. Lifun sjúklinga með krabbameinager hefur að meðaltali verið undir tveimur árum eftir kerfislæga krabbameinslyfjameðferð með eða án ...
  • Bergmann, Asa Unnur; Þórkelsson, Þórður (2020-03-04)
    INNGANGUR Nýburagula orsakast af auknu magni gallrauða í vefjum og blóði nýbura fyrstu dagana eftir fæðingu. Yfirleitt þarf ekki að meðhöndla nýburagulu en ef styrkur gallrauða í blóði verður of mikill getur hann valdið langvarandi heilaskaða. Vegna ...
  • Vilaplana-Pérez, Alba; Sidorchuk, Anna; Pérez-Vigil, Ana; Brander, Gustaf; Isoumura, Kayoko; Hesselmark, Eva; Sevilla-Cermeño, Laura; Valdimarsdóttir, Unnur Anna; Song, Huan; Jangmo, Andreas; Kuja-Halkola, Ralf; D'Onofrio, Brian M.; Larsson, Henrik; Garcia-Soriano, Gemma; Mataix-Cols, David; Fernández de la Cruz, Lorena (2020-12-01)
    Importance: Posttraumatic stress disorder (PTSD) has been associated with impaired educational performance. Previous studies on the disorder could not control for important measured and unmeasured confounders. Objective: To prospectively investigate ...
  • Li, Yuchen; Sjölander, Arvid; Song, Huan; Cnattingius, Sven; Fang, Fang; Yang, Qian; Fernández de la Cruz, Lorena; Mataix-Cols, David; Brander, Gustaf; Li, Jiong; Zhang, Wei; Fall, Katja; D’Onofrio, Brian M.; Almqvist, Catarina; Lichtenstein, Paul; Valdimarsdóttir, Unnur Anna; Lu, Donghao (2022-01-01)
    Little is known about the contribution of pregnancy-related parental and perinatal factors to the development of stress-related disorders. We aimed to investigate whether parental/perinatal adversities entail higher risks of stress-related disorders ...
  • Lárusdóttir, Katrín Júniána; Guðmundsson, Hjalti J.; Johnsen, Árni; Sigurðsson, Martin Ingi; Guðbjartsson, Tómas; Guomundsdóttir, Ingibjörg Jóna (2021-03)
    INNGANGUR Ósæðarlokuþrengsl eru algengasti lokusjúkdómurinn á Vesturlöndum. Hefðbundin meðferð við alvarlegum þrengslum hefur verið opin ósæðarlokuskipti en síðastliðin ár hefur ósæðarlokuísetning með þræðingartækni (TAVI) rutt sér til rúms hér á landi ...
  • Axelsson, Gísli Þór; Eyþórsson, Elías Sæbjörn; Harðardóttir, Hrönn; Guðmundsson, Gunnar; Hansdóttir, Sif (2020-12)
    INNGANGUR Heimsfaraldur COVID-19-sjúkdóms af völdum SARS-CoV-2 hefur valdið miklu álagi á heilbrigðiskerfi um allan heim og aðgerðir vegna hans valdið miklu efnahagstjóni. Alvarlegum sjúkdómi fylgir yfirleitt lungnabólga og fylgikvillar frá lungum eru ...
  • Andersen, Karl; Aspelund, Thor; Gudmundsson, Elias Freyr; Sigurdsson, Gunnar; Sigurdsson, Sigurdur; Björnsdottir, Gudlaug; Thorsson, Bolli; Sigurdsson, Gunnar; Hardarsson, Thordur; Gudnason, Vilmundur (2022-07-07)
    INNGANGUR Lágt menntunarstig hefur verið tengt óhagstæðri samsetningu áhættuþátta kransæðasjúkdóma. Þessu fylgir aukin áhætta á hjartaáföllum hjá minna menntuðum. Litlar upplýsingar eru til um samband menntunarstigs við alvarleika æðakölkunarsjúkdóma. ...
  • Gautadottir, Kolfinna; Gudmundsdottir, Ingibjorg Jona; Sigurdsson, Martin Ingi; Andersen, Karl (2022-10-04)
    INNGANGUR Nýgengi bráðs hjartadreps hefur lækkað í almennu þýði á undanförnum áratugum en margt bendir til þess að þetta eigi ekki við um yngstu aldurshópana. Markmið þessarar rannsóknar var að kanna nýgengi, áhættuþætti og horfur eftir brátt hjartadrep ...
  • GEMO Study Collaborators; EMBRACE Collaborators; kConFab Investigators; HEBON Investigators; Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (2021-07-28)
    BACKGROUND: Recent population-based female breast cancer and prostate cancer polygenic risk scores (PRS) have been developed. We assessed the associations of these PRS with breast and prostate cancer risks for male BRCA1 and BRCA2 pathogenic variant ...
  • Halldórsson, Arnljótur Björn; Axelsson, Gísli Þór; Jónsson, Helgi; Ísaksson, Jóhann Davíð; Harðardóttir, Hrönn; Guðmundsson, Gunnar; Hansdóttir, Sif (2021-10)
    Introduction Infections due to COVID-19 can lead to life threatening pneumonia. Accompanying severe disease are more prominent pulmonary changes on Computed Tomography (CT) scan of the chest. The goal of this study was to describe pulmonary CT changes ...
  • Wang, Junren; Zhu, Jianwei; Yang, Huazhen; Hu, Yao; Sun, Yajing; Ying, Zhiye; Qu, Yuanyuan; Valdimarsdottir, Unnur; Fang, Fang; Song, Huan (2021-06-04)
    Objective To assess the impact of the COVID-19 outbreak on cardiovascular disease (CVD) related mortality and hospitalisation. Design Community-based prospective cohort study. Setting The UK Biobank. Participants 421 372 UK Biobank participants who ...
  • Yang, Qian; Sjölander, Arvid; Li, Yuchen; Viktorin, Alexander; Bertone-Johnson, Elizabeth R.; Ye, Weimin; Fang, Fang; Valdimarsdóttir, Unnur A.; Lu, Donghao (2021-05-26)
    Background: Premenstrual disorders, including premenstrual syndrome and premenstrual dysphoric disorder, are suggested to be correlated with suicidal behavior and accidents in cross-sectional and retrospective studies. However, prospective data are ...
  • Hu, Yihan; Yang, Huazhen; Hou, Can; Chen, Wenwen; Zhang, Hanyue; Ying, Zhiye; Hu, Yao; Sun, Yajing; Qu, Yuanyuan; Feychting, Maria; Valdimarsdóttir, Unnur Anna; Song, Huan; Fang, Fang (2022-01-07)
    Background: An increased susceptibility to COVID-19 has been suggested for individuals with neurodegenerative diseases, but data are scarce from longitudinal studies. Methods: In this community-based cohort study, we included 96,275 participants of the ...
  • Vonk, Jet M.J.; Greving, Jacoba P.; Gudnason, Vilmundur; Launer, Lenore J.; Geerlings, Mirjam I. (2021-07-25)
    We aimed to evaluate the external performance of prediction models for all-cause dementia or AD in the general population, which can aid selection of high-risk individuals for clinical trials and prevention. We identified 17 out of 36 eligible published ...
  • the Benign Esophageal Perforation Collaborative Group (2020-07-17)
    BACKGROUND: Time of diagnosis (TOD) of benign esophageal perforation is regarded as an important risk factor for clinical outcome, although convincing evidence is lacking. The aim of this study is to assess whether time between onset of perforation and ...
  • Ajjampur, Sitara S.R.; Kaliappan, Saravanakumar Puthupalayam; Halliday, Katherine E.; Palanisamy, Gokila; Farzana, Jasmine; Manuel, Malathi; Abraham, Dilip; Laxmanan, Selvi; Aruldas, Kumudha; Rose, Anuradha; Kennedy, David S.; Oswald, William E.; Pullan, Rachel L.; Galagan, Sean R.; Ásbjörnsdóttir, Kristjana Hrönn; Anderson, Roy M.; Muliyil, Jayaprakash; Sarkar, Rajiv; Kang, Gagandeep; Walson, Judd L. (2021-04-30)
    Since 2015, India has coordinated the largest school-based deworming program globally, targeting soil-transmitted helminths (STH) in ~250 million children aged 1 to 19 years twice yearly. Despite substantial progress in reduction of morbidity associated ...
  • Avokpaho, Euripide F.G.A.; Houngbégnon, Parfait; Accrombessi, Manfred; Atindégla, Eloïc; Yard, Elodie; Means, Arianna Rubin; Kennedy, David S.; Littlewood, D. Timothy J.; Garcia, André; Massougbodji, Achille; Galagan, Sean R.; Walson, Judd L.; Cottrell, Gilles; Ibikounlé, Moudachirou; Ásbjörnsdóttir, Kristjana Hrönn; Luty, Adrian J.F. (2021-08-17)
    Background Despite several years of school-based MDA implementation, STH infections remain an important public health problem in Benin, with a country-wide prevalence of 20% in 2015. The DeWorm3 study is designed to assess the feasibility of using ...
  • Hjaltadóttir, Katrín; Haraldsdóttir, Kristín Huld; Möller, Páll Helgi (2020-10)
    Ágrip Gallsteinar og fylgikvillar þeirra eru með algengustu innlagnarástæðum á skurðdeildir. Meðalalgengi gallsteina er um 20% og virðist sem innlögnum og aðgerðum vegna þeirra fari fjölgandi. Gallsteinar myndast yfirleitt í gallblöðrunni en geta einnig ...
  • Nicoletti, Paola; Devarbhavi, Harshad; Goel, Ashish; Venkatesan, Radha; Eapen, Chundamannil E.; Grove, Jane I.; Zafer, Samreen; Björnsson, Einar Stefán; Lucena, M. Isabel; Andrade, Raul J.; Pirmohamed, Munir; Wadelius, Mia; Larrey, Dominique; Maitland-van der Zee, Anke Hilse; Ibanez, Luisa; Watkins, Paul B.; Daly, Ann K.; Aithal, Guruprasad P. (2021-04)
    Drug-induced liver injury (DILI) is a complication of treatment with antituberculosis (TB) drugs, especially in isoniazid (INH)-containing regimens. To investigate genetic risk factors, we performed a genomewide association study (GWAS) involving anti-TB ...