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Browsing by Subject "Prospective Studies"

Browsing by Subject "Prospective Studies"

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    Adverse health consequences of undiagnosed hearing loss at middle age : A prospective cohort study with the UK Biobank 
    Xu, Shishi; Hou, Can; Han, Xin; Hu, Yao; Yang, Huazhen; Shang, Yanan; Chen, Wenwen; Zeng, Yu; Ying, Zhiye; Sun, Yajing; Qu, Yuanyuan; Lu, Yu; Fang, Fang; Valdimarsdóttir, Unnur A.; Song, Huan (2023-08)
    Objectives: Hearing impairment is common in the middle-aged population but remains largely undiagnosed and untreated. The knowledge about to what extent and how hearing impairment matters for health is currently lacking. Thus, we aimed to comprehensively ...
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    Association between adverse childhood experiences and premenstrual disorders : a cross-sectional analysis of 11,973 women 
    Yang, Qian; Þórðardóttir, Edda Björk; Hauksdóttir, Arna; Aspelund, Thor; Jakobsdóttir, Jóhanna; Halldorsdottir, Thorhildur; Tómasson, Gunnar; Rúnarsdóttir, Harpa; Daníelsdóttir, Hilda Björk; Bertone-Johnson, Elizabeth R; Sjölander, Arvid; Fang, Fang; Lu, Donghao; Valdimarsdóttir, Unnur Anna (2022-02-21)
    Background: Childhood abuse and neglect have been associated with premenstrual disorders (PMDs), including premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD). However, the associations of other adverse childhood experiences (ACEs) ...
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    Association between Childhood Body Size and Premenstrual Disorders in Young Adulthood 
    Lu, Donghao; Aleknaviciute, Jurate; Kamperman, Astrid M.; Tamimi, Rulla M.; Ludvigsson, Jonas F.; Valdimarsdóttir, Unnur A.; Bertone-Johnson, Elizabeth R. (2022-03-01)
    Importance: Emerging data suggest that more than two-thirds of premenstrual disorders (PMDs), including premenstrual syndrome and premenstrual dysphoric disorder, have symptom onset during the teen years. Adulthood adiposity has been associated with ...
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    Cardiovascular-related deaths at the beginning of the COVID-19 outbreak : A prospective analysis based on the UK Biobank 
    Wang, Junren; Zhu, Jianwei; Yang, Huazhen; Hu, Yao; Sun, Yajing; Ying, Zhiye; Qu, Yuanyuan; Valdimarsdottir, Unnur; Fang, Fang; Song, Huan (2021-06-04)
    Objective To assess the impact of the COVID-19 outbreak on cardiovascular disease (CVD) related mortality and hospitalisation. Design Community-based prospective cohort study. Setting The UK Biobank. Participants 421 372 UK Biobank participants who ...
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    Challenges in migrant women’s maternity care in a high-income country : A population-based cohort study of maternal and perinatal outcomes 
    Guðmundsdóttir, Embla Ýr; Gottfreðsdóttir, Helga; Hálfdánsdóttir, Berglind; Nieuwenhuijze, Marianne; Gissler, Mika; Einarsdóttir, Kristjana (2021-09)
    INTRODUCTION: This study aims to explore maternal and perinatal outcomes of migrant women in Iceland. MATERIAL AND METHODS: This prospective population-based cohort study included women who gave birth to a singleton in Iceland between 1997 and 2018, ...
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    Changes in the incidence of invasive disease due to Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis during the COVID-19 pandemic in 26 countries and territories in the Invasive Respiratory Infection Surveillance Initiative : a prospective analysis of surveillance data 
    Brueggemann, Angela B.; Jansen van Rensburg, Melissa J.; Shaw, David; McCarthy, Noel D.; Jolley, Keith A.; Maiden, Martin C.J.; van der Linden, Mark P.G.; Amin-Chowdhury, Zahin; Bennett, Désirée E.; Borrow, Ray; Brandileone, Maria Cristina C.; Broughton, Karen; Campbell, Ruth; Cao, Bin; Casanova, Carlo; Choi, Eun Hwa; Chu, Yiu Wai; Clark, Stephen A.; Claus, Heike; Coelho, Juliana; Corcoran, Mary; Cottrell, Simon; Cunney, Robert J.; Dalby, Tine; Davies, Heather; de Gouveia, Linda; Deghmane, Ala Eddine; Demczuk, Walter; Desmet, Stefanie; Drew, Richard J.; du Plessis, Mignon; Erlendsdóttir, Helga; Fry, Norman K.; Fuursted, Kurt; Gray, Steve J.; Henriques-Normark, Birgitta; Hale, Thomas; Hilty, Markus; Hoffmann, Steen; Humphreys, Hilary; Ip, Margaret; Jacobsson, Susanne; Johnston, Jillian; Kozakova, Jana; Kristinsson, Karl Gústaf; Krizova, Pavla; Kuch, Alicja; Ladhani, Shamez N.; Lâm, Thiên Trí; Lebedova, Vera; Lindholm, Laura; Litt, David J.; Martin, Irene; Martiny, Delphine; Mattheus, Wesley; McElligott, Martha; Meehan, Mary; Meiring, Susan; Mölling, Paula; Morfeldt, Eva; Morgan, Julie; Mulhall, Robert M.; Muñoz-Almagro, Carmen; Murdoch, David R.; Murphy, Joy; Musilek, Martin; Mzabi, Alexandre; Perez-Argüello, Amaresh; Perrin, Monique; Perry, Malorie; Redin, Alba; Roberts, Richard; Roberts, Maria; Rokney, Assaf; Ron, Merav; Scott, Kevin J.; Sheppard, Carmen L.; Siira, Lotta; Skoczyńska, Anna; Sloan, Monica; Slotved, Hans Christian; Smith, Andrew J.; Song, Joon Young; Taha, Muhamed Kheir; Toropainen, Maija; Tsang, Dominic; Vainio, Anni; van Sorge, Nina M.; Varon, Emmanuelle; Vlach, Jiri; Vogel, Ulrich; Vohrnova, Sandra; von Gottberg, Anne; Zanella, Rosemeire C.; Zhou, Fei (2021-06)
    Background: Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis, which are typically transmitted via respiratory droplets, are leading causes of invasive diseases, including bacteraemic pneumonia and meningitis, and of secondary ...
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    Clinical indications of premenstrual disorders and subsequent risk of injury : a population-based cohort study in Sweden 
    Yang, Qian; Sjölander, Arvid; Li, Yuchen; Viktorin, Alexander; Bertone-Johnson, Elizabeth R.; Ye, Weimin; Fang, Fang; Valdimarsdóttir, Unnur A.; Lu, Donghao (2021-05-26)
    Background: Premenstrual disorders, including premenstrual syndrome and premenstrual dysphoric disorder, are suggested to be correlated with suicidal behavior and accidents in cross-sectional and retrospective studies. However, prospective data are ...
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    Comparative effectiveness of anti-IL5 and anti-IgE biologic classes in patients with severe asthma eligible for both 
    Pfeffer, Paul E; Ali, Nasloon; Murray, Ruth; Ulrik, Charlotte; Tran, Trung N; Maspero, Jorge; Peters, Matthew; Christoff, George C; Sadatsafavi, Mohsen; Torres-Duque, Carlos A; Altraja, Alan; Lehtimäki, Lauri; Papadopoulos, Nikolaos G; Salvi, Sundeep; Costello, Richard W; Cushen, Breda; Heffler, Enrico; Iwanaga, Takashi; Al-Ahmad, Mona; Larenas-Linnemann, Désirée; Kuna, Piotr; Fonseca, João A; Al-Lehebi, Riyad; Rhee, Chin Kook; Perez-de-Llano, Luis; Perng Steve, Diahn-Warng; Mahboub, Bassam; Wang, Eileen; Goh, Celine; Lyu, Juntao; Newell, Anthony; Alacqua, Marianna; Belevskiy, Andrey S; Bhutani, Mohit; Bjermer, Leif; Björnsdóttir, Unnur Steina; Bourdin, Arnaud; Bulow, Anna von; Busby, John; Canonica, Giorgio Walter; Cosio, Borja G; Dorscheid, Delbert R; Muñoz-Esquerre, Mariana; FitzGerald, J Mark; Gil, Esther Garcia; Gibson, Peter G; Heaney, Liam G; Hew, Mark; Hilberg, Ole; Hoyte, Flavia; Jackson, David J; Koh, Mariko Siyue; Ko, Hsin-Kuo Bruce; Lee, Jae Ha; Lehmann, Sverre; Chaves Loureiro, Cláudia; Lúðvíksdóttir, Dóra; Menzies-Gow, Andrew N; Mitchell, Patrick; Papaioannou, Andriana I; Popov, Todor A; Porsbjerg, Celeste M; Salameh, Laila; Sirena, Concetta; Taillé, Camille; Taube, Christian; Tohda, Yuji; Wechsler, Michael E; Price, David B (2023-07)
    BACKGROUND: Patients with severe asthma may present with characteristics representing overlapping phenotypes, making them eligible for more than one class of biologic. Our aim was to describe the profile of adult patients with severe asthma eligible ...
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    The CRTAC1 Protein in Plasma Is Associated With Osteoarthritis and Predicts Progression to Joint Replacement: A Large-Scale Proteomics Scan in Iceland : A Large-Scale Proteomics Scan in Iceland 
    Styrkarsdottir, Unnur; Lund, S.H.; Saevarsdottir, S.; Magnusson, M.I.; Gunnarsdottir, K.; Norddahl, Gudmundur L.; Frigge, Michael L.; Ivarsdottir, E.V.; Bjornsdottir, Gyda; Holm, Hilma; Thorgeirsson, Guðmundur; Rafnar, T.; Jonsdottir, I.; Ingvarsson, T.; Jonsson, H.; Sulem, P.; Thorsteinsdottir, U.; Gudbjartsson, Daniel Fannar; Stefansson, K.; Thorgeirsson, Gudmundur; Ingvarsson, Þorvaldur (2021-11)
    Objective: Biomarkers for diagnosis and progression of osteoarthritis (OA) are lacking. This study was undertaken to identify circulating biomarkers for OA that could predict disease occurrence and/or progression to joint replacement. Methods: Using ...
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    Defining new reference intervals for serum free light chains in individuals with chronic kidney disease : Results of the iStopMM study 
    Long, Þórir Einarsson; Indriðason, Ólafur Skúli; Pálsson, Runólfur; Rögnvaldsson, Sæmundur; Löve, Þorvarður Jón; Thorsteinsdóttir, Sigrún; Sverrisdóttir, Ingigerður S; Viðarsson, Brynjar; Önundarson, Páll Torfi; Agnarsson, Bjarni Agnar; Sigurðardóttir, Margrét; Þorsteinsdóttir, Ingunn; Ólafsson, Ísleifur; Thordardottir, Asdis Rosa; Eyþórsson, Elías Sæbjörn; Jónsson, Ásbjörn; Gíslason, Gauti Kjartan; Ólafsson, Andri; Steingrímsdóttir, Hlíf; Hultcrantz, Malin; Durie, Brian G.M.; Harding, Stephen; Landgren, Ola; Kristinsson, Sigurður Yngvi (2022-09-14)
    Serum free light chain (FLC) concentration is greatly affected by kidney function. Using a large prospective population-based cohort, we aimed to establish a reference interval for FLCs in persons with chronic kidney disease (CKD). A total of 75422 ...
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    Dual or single antiplatelet therapy after coronary surgery for acute coronary syndrome (TACSI trial) : Rationale and design of an investigator-initiated, prospective, multinational, registry-based randomized clinical trial 
    Malm, Carl Johan; Alfredsson, Joakim; Erlinge, David; Guðbjartsson, Tómas; Gunn, Jarmo; James, Stefan; Møller, Christian H; Nielsen, Susanne J; Sartipy, Ulrik; Tønnessen, Theis; Jeppsson, Anders (2023-05)
    The TACSI trial (ClinicalTrials.gov Identifier: NCT03560310) tests the hypothesis that 1-year treatment with dual antiplatelet therapy with acetylsalicylic acid (ASA) and ticagrelor is superior to only ASA after isolated coronary artery bypass grafting ...
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    Endothelial Cell Phenotypes Demonstrate Different Metabolic Patterns and Predict Mortality in Trauma Patients 
    Henriksen, Hanne H.; Marín de Mas, Igor; Nielsen, Lars K.; Krocker, Joseph; Stensballe, Jakob; Karvelsson, Sigurður T.; Secher, Niels H.; Rolfsson, Óttar; Wade, Charles E.; Johansson, Pär I. (2023-01-23)
    In trauma patients, shock-induced endotheliopathy (SHINE) is associated with a poor prognosis. We have previously identified four metabolic phenotypes in a small cohort of trauma patients (N = 20) and displayed the intracellular metabolic profile of ...
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    Feasibility of MRI to assess differences in ophthalmic artery blood flow rate in normal tension glaucoma and healthy controls 
    Kristiansen, Martin; Lindén, Christina; Qvarlander, Sara; Wåhlin, Anders; Ambarki, Khalid; Hallberg, Per; Eklund, Anders; Jóhannesson, Gauti (2020-11-19)
    Purpose: To examine feasibility of phase-contrast magnetic resonance imaging (PCMRI) and to assess blood flow rate in the ophthalmic artery (OA) in patients with normal tension glaucoma (NTG) compared with healthy controls. Methods: Sixteen patients ...
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    Health-related quality of life as associated with asthma control, psychological status and insomnia 
    Rask-Andersen, Anna; Leander, Mai; Sundbom, Fredrik; Lampa, Erik; Oudin, Anna; Leynaert, Bénédicte; Svanes, Cecilie; Gíslason, Þórarinn; Torén, Kjell; Janson, Christer (2022)
    BACKGROUND: Asthma is associated not only with lower health-related quality of life (HRQL) but also with psychological health and insomnia. The aim of this study was to investigate associations between HRQL, asthma symptoms, psychological status and ...
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    High Rate of Hepatitis C Virus Reinfection Among Recently Injecting Drug Users: : Results From the TraP Hep C Program-A Prospective Nationwide, Population-Based Study 
    TraP Hep C group (2022-04-19)
    BACKGROUND: The Treatment as Prevention for Hepatitis C program started in 2016 in Iceland, offering treatment with direct-acting antivirals to hepatitis C virus (HCV)-infected individuals. Reinfections through injection drug use (IDU) can hamper ...
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    A meta-analysis uncovers the first sequence variant conferring risk of Bell’s palsy 
    Skuladottir, Astros Th; Bjornsdottir, Gyda; Thorleifsson, Gudmar; Walters, G. Bragi; Nawaz, Muhammad Sulaman; Moore, Kristjan Helgi Swerford; Olason, Pall I.; Thorgeirsson, Thorgeir E.; Sigurpalsdottir, Brynja; Sveinbjornsson, Gardar; Eggertsson, Hannes P.; Magnusson, Sigurdur H.; Oddsson, Asmundur; Bjornsdottir, Anna; Vikingsson, Arnor; Sveinsson, Olafur A.; Hrafnsdottir, Maria G.; Sigurdardottir, Gudrun R.; Halldorsson, Bjarni V.; Hansen, Thomas Folkmann; Paarup, Helene; Erikstrup, Christian; Nielsen, Kaspar; Klokker, Mads; Bruun, Mie Topholm; Sorensen, Erik; Banasik, Karina; Burgdorf, Kristoffer S.; Pedersen, Ole Birger; Ullum, Henrik; Jonsdottir, Ingileif; Stefansson, Hreinn; Stefansson, Kari (2021-02-18)
    Bell’s palsy is the most common cause of unilateral facial paralysis and is defined as an idiopathic and acute inability to control movements of the facial muscles on the affected side. While the pathogenesis remains unknown, previous studies have ...
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    A new framework for advancing in drug-induced liver injury research. The Prospective European DILI Registry 
    Björnsson, Einar Stefán; Stephens, Camilla; Atallah, Edmond; Robles-Diaz, Mercedes; Alvarez-Alvarez, Ismael; Gerbes, Alexander; Weber, Sabine; Stirnimann, Guido; Kullak-Ublick, Gerd; Cortez-Pinto, Helena; Grove, Jane I.; Lucena, M. Isabel; Andrade, Raul J.; Aithal, Guruprasad P. (2023-01-01)
    Background & Aims: No multi-national prospective study of drug-induced liver injury (DILI) has originated in Europe. The design of a prospective European DILI registry, clinical features and short-term outcomes of the cases and controls is reported. ...
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    Nicotinamide Prevents Retinal Vascular Dropout in a Rat Model of Ocular Hypertension and Supports Ocular Blood Supply in Glaucoma Patients 
    Gustavsson, Simon T.; Enz, Tim J.; Tribble, James R.; Nilsson, Mattias; Lindqvist, Anna; Lindén, Christina; Hagström, Anna; Rutigliani, Carola; Lardner, Emma; Stålhammar, Gustav; Williams, Pete A.; Jóhannesson, Gauti (2023-11-01)
    PURPOSE: To investigate whether nicotinamide (NAM) modulates retinal vasculature in glaucoma. METHODS: This was a prospective controlled clinical trial investigating animal and human histopathology. Participants included normotensive and ocular ...
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    Nordic dietary patterns and cardiometabolic outcomes : a systematic review and meta-analysis of prospective cohort studies and randomised controlled trials 
    Massara, Paraskevi; Zurbau, Andreea; Glenn, Andrea J.; Chiavaroli, Laura; Khan, Tauseef A.; Viguiliouk, Effie; Mejia, Sonia Blanco; Comelli, Elena M.; Chen, Victoria; Schwab, Ursula; Risérus, Ulf; Uusitupa, Matti; Aas, Anne Marie; Hermansen, Kjeld; Thorsdottir, Inga; Rahelić, Dario; Kahleová, Hana; Salas-Salvadó, Jordi; Kendall, Cyril W.C.; Sievenpiper, John L. (2022-08-26)
    AIMS/HYPOTHESIS: Nordic dietary patterns that are high in healthy traditional Nordic foods may have a role in the prevention and management of diabetes. To inform the update of the EASD clinical practice guidelines for nutrition therapy, we conducted ...
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    Old question revisited : Are high-protein diets safe in pregnancy? 
    Halldórsson, Þórhallur Ingi; Birgisdóttir, Bryndís Eva; Brantsæter, Anne Lise; Meltzer, Helle Margrete; Haugen, Margaretha; Þórsdóttir, Inga; Ólafsdóttir, Anna Sigríður; Olsen, Sjurdur F. (2021-01-29)
    BACKGROUND: A previous randomized dietary intervention in pregnant women from the 1970s, the Harlem Trial, reported retarded fetal growth and excesses of very early preterm births and neonatal deaths among those receiving high-protein supplementation. ...