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Browsing by Author "Sigurdsson, Engilbert"

Browsing by Author "Sigurdsson, Engilbert"

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  • Guðmundsson, Ólafur Ó.; Walters, G. Bragi; Ingason, Andrés; Johansson, Stefan; Zayats, Tetyana; Athanasiu, Lavinia; Sonderby, Ida Elken; Gústafsson, Ómar; Nawaz, Muhammad S.; Jónsson, Guðbjörn F.; Jonsson, Lina; Knappskog, Per-Morten; Ingvarsdóttir, Ester; Daviðsdóttir, Katrín; Djurovic, Srdjan; Knudsen, Gun Peggy Strømstad; Askeland, Ragna Bugge; Haraldsdóttir, Gyða S.; Baldursson, Gísli; Magnússon, Páll; Sigurdsson, Engilbert; Gudbjartsson, Daniel; Stefansson, Hreinn; Andreassen, Ole A.; Haavik, Jan; Reichborn-Kjennerud, Ted; Stefansson, Kari (Springer Science and Business Media LLC, 2019-10-17)
    Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable common childhood-onset neurodevelopmental disorder. Some rare copy number variations (CNVs) affect multiple neurodevelopmental disorders such as intellectual disability, autism ...
  • Ingimarsson, Oddur; MacCabe, James; Haraldsson, Magnús; Jónsdóttir, Halldóra; Sigurdsson, Engilbert (Springer Nature, 2016-12)
    Background Data on the haematological outcomes of patients who continue clozapine treatment following neutropenia are very rare as even mild neutropenia results in mandatory discontinuation of clozapine in most countries. However, in Iceland where ...
  • Reginsson, Gunnar W.; Ingason, Andrés; Euesden, Jack; Bjornsdottir, Gyda; Ólafsson, Sigurgeir; Sigurdsson, Engilbert; Óskarsson, Högni; Tyrfingsson, Þórarinn; Rúnarsdóttir, Valgerður; Hansdóttir, Ingunn; Steinberg, Stacy; Stefánsson, Hreinn; Gudbjartsson, Daniel; Thorgeirsson, Thorgeir; Stefansson, Kari (Wiley, 2017-02-23)
    We use polygenic risk scores (PRSs) for schizophrenia (SCZ) and bipolar disorder (BPD) to predict smoking, and addiction to nicotine, alcohol or drugs in individuals not diagnosed with psychotic disorders. Using PRSs for 144 609 subjects, including 10 ...
  • Mullins, Niamh; Ingason, Andrés; Porter, Heather; Euesden, Jack; Gillett, Alexandra; Ólafsson, Sigurgeir; Gudbjartsson, Daniel; Lewis, Cathryn M.; Sigurdsson, Engilbert; Sæmundsen, Evald E.; Guðmundsson, Ólafur Ó.; Frigge, Michael L.; Kong, Augustine; Helgason, Agnar; Walters, G. Bragi; Gústafsson, Ómar; Stefánsson, Hreinn; Stefansson, Kari (Springer Nature, 2017-06-13)
    The persistence of common, heritable psychiatric disorders that reduce reproductive fitness is an evolutionary paradox. Here, we investigate the selection pressures on sequence variants that predispose to schizophrenia, autism, bipolar disorder, major ...