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Browsing by Subject "Krabbamein"

Browsing by Subject "Krabbamein"

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  • Cozzi-Lepri, A; Zangerle, R; Machala, L; Zilmer, K; Ristola, M; Pradier, C; Kirk, O; Sambatakou, H; Fätkenheuer, G; Yust, I; Schmid, P; Gottfredsson, Magnus; Khromova, I; Jilich, D; Flisiak, R; Smidt, J; Rozentale, B; Radoi, R; Losso, MH; Lundgren, JD; Mocroft, A (Wiley, 2017-10-06)
    Objectives There are currently few data on the long‐term risk of cancer and death in individuals taking raltegravir (RAL). The aim of this analysis was to evaluate whether there is evidence for an association. Methods The EuroSIDA cohort was divided ...
  • Islind, Anna Sigridur; Johansson, Victoria; Vallo Hult, Helena; Alsén, Pia; Andreasson, Emma; Angenete, Eva; Gellerstedt, Martin (Springer Science and Business Media LLC, 2020-10-12)
    Purpose The number of colorectal cancer patient survivors is increasing. Information and support during and after treatment are requested by patients, but questions remain on what to provide. The aim of this study was to understand what informational ...
  • Larat, Clémence (University of Iceland, School of Health Sciences, Faculty of Medicine, 2025-06-02)
    Autophagy is a cellular degradation process, important for maintaining cellular homeostasis. It has been shown to be involved in cancer initiation and development, either in a tumour-suppressive or promotive manner. The protein ATG7 is known to be ...
  • de Fine Licht, Sofie; Rugbjerg, Kathrine; Gudmundsdottir, Thorgerdur; Bonnesen, Trine G.; Asdahl, Peter Haubjerg; Holmqvist, Anna Sällfors; Madanat-Harjuoja, Laura; Tryggvadottir, Laufey; Wesenberg, Finn; Hasle, Henrik; Winther, Jeanette F.; Olsen, Jørgen H. (Public Library of Science (PLoS), 2017-05-09)
    Background Survivors of childhood cancer are at increased risk for a wide range of late effects. However, no large population-based studies have included the whole range of somatic diagnoses including subgroup diagnoses and all main types of childhood ...
  • Zimta, Alina-Andreea; Sigurjonsson, Olafur Eysteinn; Gulei, Diana; Tomuleasa, Ciprian (MDPI AG, 2020-08-15)
    Nowadays, advancements in the oncology sector regarding diagnosis methods allow us to specifically detect an increased number of cancer patients, some of them in incipient stages. However, one of the main issues consists of the invasive character of ...
  • Anderson, Kimberley (University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-04)
    Transcriptional regulatory mechanisms drive the maturation of B cells to plasma cells, with a dramatic transcriptional rewiring taking place during the transition. This rewiring is dependent on a number of factors, including the transcription factor B ...
  • Zhu, Jianwei; Sjölander, Arvid; Fall, Katja; Valdimarsdottir, Unnur; Fang, Fang (Springer Nature, 2018-03-27)
    Background Whether the emotional distress around cancer diagnosis is associated with the long-term outcomes and care utilization is unknown. We aimed to examine the association of mental disorders around cancer diagnosis with the hospital admission ...
  • Schijns, Virgil; Fernández‐Tejada, Alberto; Barjaktarović, Žarko; Bouzalas, Ilias; Brimnes, Jens; Chernysh, Sergey; Gizurarson, Sveinbjorn; Gursel, Ihsan; Jakopin, Žiga; Lawrenz, Maria; Nativi, Cristina; Paul, Stephane; Pedersen, Gabriel Kristian; Rosano, Camillo; Ruiz‐de‐Angulo, Ane; Slütter, Bram; Thakur, Aneesh; Christensen, Dennis; Lavelle, Ed C. (Wiley, 2020-06-28)
    Therapeutic vaccination offers great promise as an intervention for a diversity of infectious and non-infectious conditions. Given that most chronic health conditions are thought to have an immune component, vaccination can at least in principle be ...
  • Hjaltalin, Valgerdur; Pogenberg, Vivian; Ostacolo, Kevin; Palsson, Arnar; Ogmundsdottir, Margret H. (Informa, 2022-09-07)
    The E1-like enzyme ATG7 belongs to a group of ATG proteins that mediate the autophagy process. Autophagy is a highly conserved degradation pathway important for maintaining homeostasis in eukaryotic cells. Here, we study the evolution of E1 enzymes and ...
  • Farioli, Andrea; Straif, Kurt; Brandi, Giovanni; Curti, Stefania; Kjaerheim, Kristina; Martinsen, Jan Ivar; Sparen, Pär; Tryggvadottir, Laufey; Weiderpass, Elisabete; Biasco, Guido; Violante, Francesco Saverio; Mattioli, Stefano; Pukkala, Eero (BMJ, 2017-11-13)
    Objectives To assess the association between occupational exposure to asbestos and the risk of cholangiocarcinoma (CC). Methods We conducted a case–control study nested in the Nordic Occupational Cancer (NOCCA) cohort. We studied 1458 intrahepatic ...
  • Pálsdóttir, Edda; Lund, Sigrún Helga; Ásgeirsson, Kristján Skúli (SAGE Publications, 2018-05-14)
    Background and Aims: In Iceland, oncoplastic breast-conservation surgery has been performed since 2008. The aim of this population-based study was to assess and compare the efficacy and patient satisfaction of standard breast-conservation surgery with ...
  • Campbell, Peter J.; Stefansson, Olafur (Springer Science and Business Media LLC, 2020-02-05)
    Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale1,2,3. Here we report the integrative analysis of 2,658 whole-cancer genomes and their ...
  • Gunnell, Anthony S.; Joyce, Sarah; Tomlin, Stephania; Taaffe, Dennis R.; Cormie, Prue; Newton, Robert U.; Joseph, David; Spry, Nigel; Einarsdottir, Kristjana; Galvão, Daniel A. (Frontiers Media SA, 2017-02-14)
    Evidence suggests physical activity improves prognosis following cancer diagnosis; however, evidence regarding prognosis in long-term survivors of cancer is scarce. We assessed physical activity in 1,589 cancer survivors at an average 8.8 years following ...
  • Mikropoulos, Christos; Selkirk, Christina G Hutten; Saya, Sibel; Bancroft, Elizabeth; Vertosick, Emily; Dadaev, Tokhir; Brendler, Charles; Page, Elizabeth; Dias, Alexander; Evans, D Gareth; Rothwell, Jeanette; Maehle, Lovise; Axcrona, Karol; Richardson, Kate; Eccles, Diana; Jensen, Thomas; Osther, Palle J; van Asperen, Christi J; Vasen, Hans; Kiemeney, Lambertus A; Ringelberg, Janneke; Cybulski, Cezary; Wokolorczyk, Dominika; Hart, Rachel; Glover, Wayne; Lam, Jimmy; Taylor, Louise; Salinas, Monica; Feliubadaló, Lidia; Oldenburg, Rogier; Cremers, Ruben; Verhaegh, Gerald; van Zelst-Stams, Wendy A; Oosterwijk, Jan C; Cook, Jackie; Rosario, Derek J; Buys, Saundra S; Conner, Tom; Domchek, Susan; Powers, Jacquelyn; Ausems, Margreet GEM; Teixeira, Manuel R; Maia, Sofia; Izatt, Louise; Schmutzler, Rita; Rhiem, Kerstin; Foulkes, William D; Boshari, Talia; Davidson, Rosemarie; Ruijs, Marielle; Helderman-van den Enden, Apollonia TJM; Andrews, Lesley; Walker, Lisa; Snape, Katie; Henderson, Alex; Jobson, Irene; Lindeman, Geoffrey J; Liljegren, Annelie; Harris, Marion; Adank, Muriel A; Kirk, Judy; Taylor, Amy; Susman, Rachel; Chen-Shtoyerman, Rakefet; Pachter, Nicholas; Spigelman, Allan; Side, Lucy; Zgajnar, Janez; Mora, Josefina; Brewer, Carole; Gadea, Neus; Brady, Angela F; Gallagher, David; van Os, Theo; Donaldson, Alan; Stefansdottir, Vigdis; Barwell, Julian; James, Paul A; Murphy, Declan; Friedman, Eitan; Nicolai, Nicola; Greenhalgh, Lynn; Obeid, Elias; Murthy, Vedang; Copakova, Lucia; McGrath, John; Teo, Soo-Hwang; Strom, Sara; Kast, Karin; Leongamornlert, Daniel A; Chamberlain, Anthony; Pope, Jenny; Newlin, Anna C; Aaronson, Neil; Ardern-Jones, Audrey; Bangma, Chris; Castro, Elena; Dearnaley, David; Eyfjörð, Jórunn Erla; Falconer, Alison; Foster, Christopher S; Gronberg, Henrik; Hamdy, Freddie C; Johannsson, Oskar; Khoo, Vincent; Lubinski, Jan; Grindedal, Eli Marie; McKinley, Joanne; Shackleton, Kylie; Mitra, Anita V; Moynihan, Clare; Rennert, Gad; Suri, Mohnish; Tricker, Karen; Moss, Sue; Kote-Jarai, Zsofia; Vickers, Andrew; Lilja, Hans; Helfand, Brian T; Eeles, Rosalind A (Springer Nature, 2018-01)
    Background: Prostate-specific antigen (PSA) and PSA-velocity (PSAV) have been used to identify men at risk of prostate cancer (PrCa). The IMPACT study is evaluating PSA screening in men with a known genetic predisposition to PrCa due to BRCA1/2 ...
  • Hálfdánarson, Óskar (University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-03-08)
    Background and aims: Proton pump inhibitors (PPIs) are commonly prescribed drugs that are used to treat acid-related disorders of the gastrointestinal tract. Over the last decade, PPI use has repeatedly been shown to be increasing worldwide, causing ...
  • Interrante, Mary K.; Segal, Hannah; Peshkin, Beth N.; Valdimarsdottir, Heiddis; Nusbaum, Rachel; Similuk, Morgan; DeMarco, Tiffani; Hooker, Gillian; Graves, Kristi; Isaacs, Claudine; Wood, Marie; McKinnon, Wendy; Garber, Judy; McCormick, Shelley; Heinzmann, Jessica; Kinney, Anita Y.; Schwartz, Marc D. (Oxford University Press (OUP), 2017-09-01)
    Background: Telephone delivery of genetic counseling is an alternative to in-person genetic counseling because it may extend the reach of genetic counseling. Previous reports have established the noninferiority of telephone counseling on short-term ...
  • Bailey, Matthew H.; Stefansson, Olafur (Springer Science and Business Media LLC, 2020-09-21)
    The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer ...
  • Jónsdóttir, Guðbjörg (University of Iceland, School of Health Sciences, Faculty of Medicine, 2021-05-21)
    Inngangur: Með tilkomu áhrifaríkari lyfja í meðhöndlun sjúklinga með mergæxli síðastliðna áratugi hefur lifun þeirra stóraukist. Þessi aukna lifun hefur leitt til aukinnar áherslu rannsakennda á langtíma afleiðingum í formi þróun annarra krabbameina. ...
  • Vésteinsdóttir, Edda (University of Iceland, School of Health Sciences, Faculty of Medicine, 2022-05)
    Sepsis is a leading cause of admission to intensive care units (ICU) worldwide and mortality rates remain high despite advances in organ support. Awareness of the syndrome has increased substantially in the past 20 years, after the publication of several ...
  • Li, Constance H.; Stefansson, Olafur (Springer Science and Business Media LLC, 2020-08-28)
    Sex differences have been observed in multiple facets of cancer epidemiology, treatment and biology, and in most cancers outside the sex organs. Efforts to link these clinical differences to specific molecular features have focused on somatic mutations ...