Opin vísindi: Síðast bætt við

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    Postnational Identities, Icelandicness and Icelandicity: Transnational and Environmental Strategies in Contemporary Art in Iceland 
    Sigurjónsdóttir, Æsa (University of Iceland, School of Humanities, Faculty of History and Philosophy, 2023-10)
    To travel north has always been a challenge for the explorer, the natural scientist, the poet, the cartographer, the photographer, and the artist. Long present in the European imaginary, Iceland’s natural phenomena has functioned to affirm an idea of ...
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    Study design for development of novel safety biomarkers of drug-induced liver injury by the translational safety biomarker pipeline (TransBioLine) consortium : a study protocol for a nested case-control study 
    TransBioLine consortium (2023-09-12)
    A lack of biomarkers that detect drug-induced liver injury (DILI) accurately continues to hinder early- and late-stage drug development and remains a challenge in clinical practice. The Innovative Medicines Initiative's TransBioLine consortium comprising ...
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    Second and third TNF inhibitors in European patients with axial spondyloarthritis : Effectiveness and impact of the reason for switching 
    Linde, Louise; Ørnbjerg, Lykke Midtbøll; Brahe, Cecilie Heegaard; Wallman, Johan Karlsson; Di Giuseppe, Daniela; Závada, Jakub; Castrejon, Isabel; Díaz-Gonzalez, Federico; Rotar, Ziga; Tomšič, Matija; Glintborg, Bente; Guðbjörnsson, Björn; Geirsson, Árni Jón; Michelsen, Brigitte; Kristianslund, Eirik Klami; Santos, Maria José; Barcelos, Anabela; Nordström, Dan; Eklund, Kari K; Ciurea, Adrian; Nissen, Michael; Akar, Servet; Hyldstrup, Lise Hejl; Krogh, Niels Steen; Hetland, Merete Lund; Østergaard, Mikkel (2023-09-20)
    OBJECTIVE: To investigate real-world effectiveness of tumor necrosis factor inhibitors (TNFi) in patients with axial spondyloarthritis (axSpA) and the association with 1) treatment line (second and third TNFi-series) and 2) reason for withdrawal from ...
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    Evaluating Prophylactic Effect of Bovine Colostrum on Intestinal Barrier Function in Zonulin Transgenic Mice : A Transcriptomic Study 
    Ásbjörnsdóttir, Birna Guðrún; Sigurðsson, Snævar; Miranda-Ribera, Alba; Fiorentino, Maria; Konno, Takumi; Lan, Jinggang; Guðmundsson, Lárus Steinþór; Gottfreðsson, Magnús; Lauth, Bertrand Andre Marc; Birgisdóttir, Bryndís Eva; Fasano, Alessio (2023-09-29)
    The intestinal barrier comprises a single layer of epithelial cells tightly joined to form a physical barrier. Disruption or compromise of the intestinal barrier can lead to the inadvertent activation of immune cells, potentially causing an increased ...
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    Furosemide versus placebo for fluid overload in intensive care patients—The randomised GODIF trial second version : Statistical analysis plan 
    Wichmann, Sine; Lange, Theis; Perner, Anders; Gluud, Christian; Itenov, Theis S.; Berthelsen, Rasmus E.; Nebrich, Lars; Wiis, Jørgen; Brøchner, Anne C.; Nielsen, Louise G.; Behzadi, Meike T.; Damgaard, Kjeld; Andreasen, Anne S.; Strand, Kristian; Järvisalo, Mikko; Strøm, Thomas; Eschen, Camilla T.; Vang, Marianne L.; Hildebrandt, Thomas; Andersen, Finn H.; Sigurðsson, Martin Ingi; Þormar, Katrín María; Thygesen, Sandra K.; Troelsen, Thomas T.; Uusalo, Panu; Jalkanen, Ville; Illum, Dorte; Sølling, Christoffer; Keus, Frederik; Pfortmueller, Carmen A.; Wahlin, Rebecka R.; Ostermann, Marlies; Aneman, Anders; Bestle, Morten H. (2024-01)
    Background: Fluid overload is associated with increased mortality in intensive care unit (ICU) patients. The GODIF trial aims to assess the benefits and harms of fluid removal with furosemide versus placebo in stable adult patients with moderate to ...
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    Meningococcal carriage in children and young adults : a cross-sectional and longitudinal study, Iceland, 2019 to 2021 
    Kristinsdóttir, Íris; Visser, Linda J.; Miellet, Willem R.; Mariman, Rob; Pluister, Gerlinde; Haraldsson, Gunnsteinn Ægir; Haraldsson, Ásgeir; Trzciński, Krzysztof; Thors, Valtýr Stefánsson (2023-09-01)
    BackgroundNeisseria meningitidis is a commensal bacterium which can cause invasive disease. Colonisation studies are important to guide vaccination strategies.AimThe study's aim was to determine the prevalence of meningococcal colonisation, duration ...
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    A population-based survey of FBN1 variants in Iceland reveals underdiagnosis of Marfan syndrome 
    Klemenzdottir, Elin Ola; Arnadottir, Gudny A; Jensson, Brynjar Orn; Jonasdottir, Adalbjorg; Katrinardottir, Hildigunnur; Fridriksdottir, Run; Jonasdottir, Aslaug; Sigurdsson, Asgeir; Gudjonsson, Sigurjon Axel; Jónsson, Jón Jóhannes; Stefánsdóttir, Vigdís Fjóla; Danielsen, Ragnar; Palsdottir, Astridur; Jonsson, Hakon; Helgason, Agnar Sturla; Magnusson, Olafur Thor; Thorsteinsdottir, Unnur; Björnsson, Hans Tómas; Stefansson, Kari; Sulem, Patrick (2023)
    Marfan syndrome (MFS) is an autosomal dominant condition characterized by aortic aneurysm, skeletal abnormalities, and lens dislocation, and is caused by variants in the FBN1 gene. To explore causes of MFS and the prevalence of the disease in Iceland ...
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    PRS-ing Forward to Identify Genetic Risk in Idiopathic Pulmonary Fibrosis 
    Blackwell, Timothy S; Guðmundsson, Gunnar (2023-10-01)
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    Optimizing pharmacotherapy and deprescribing strategies in older adults living with multimorbidity and polypharmacy : EuGMS SIG on pharmacology position paper 
    EuGMS SIG Pharmacology (2023-12)
    Inappropriate polypharmacy is highly prevalent among older adults and presents a significant healthcare concern. Conducting medication reviews and implementing deprescribing strategies in multimorbid older adults with polypharmacy are an inherently ...
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    Therapist guided, parent-led cognitive behavioural therapy (CBT) for pre-adolescent children with obsessive compulsive disorder (OCD) : a non-concurrent multiple baseline case series 
    Chessell, Chloe; Halldórsson, Brynjar; Walters, Sasha; Farrington, Alice; Harvey, Kate; Creswell, Cathy (2023-10-16)
    BACKGROUND: Cognitive behavioural therapy (CBT) including exposure and response prevention (ERP) is an effective treatment for preadolescent children with obsessive compulsive disorder (OCD); however, there is a need to increase access to this treatment ...
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    Methotrexate safety and efficacy in combination therapies in patients with early rheumatoid arthritis : a post-hoc analysis of a randomized controlled trial (NORD-STAR) 
    Lend, Kristina; Koopman, Frieda A; Lampa, Jon; Jansen, Gerrit; L, Merete Hetland; Uhlig, Till; Nordström, Dan; Nurmohamed, Michael; Guðbjörnsson, Björn; Rudin, Anna; Østergaard, Mikkel; Heiberg, Marte S; Sokka-Isler, Tuulikki; Hørslev-Petersen, Kim; Haavardsholm, Espen A; Gröndal, Gerður María; Twisk, Jos W R; van Vollenhoven, Ronald (2023-10-17)
    OBJECTIVE: To investigate methotrexate safety and influence of dose on efficacy outcomes in combination with three different biological treatments and with active conventional treatment (ACT) in early rheumatoid arthritis (RA). METHODS: This post-hoc ...
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    Adverse childhood experiences and psychological functioning among women with schizophrenia or bipolar disorder : population-based study 
    Köhler-Forsberg, Ole; Ge, Fenfen; Hauksdóttir, Arna; Þórðardóttir, Edda Björk; Ásbjörnsdóttir, Kristjana Hrönn; Rúnarsdóttir, Harpa; Tómasson, Gunnar; Jakobsdóttir, Jóhanna; Guðmundsdóttir, Berglind; Björnsson, Andri Steinþór; Sigurðsson, Engilbert; Aspelund, Thor; Valdimarsdóttir, Unnur Anna (2024-01)
    BACKGROUND: Adverse childhood experiences (ACEs) are well-known risk factors for schizophrenia and bipolar disorder. AIMS: The aim was to study the associations between specific ACEs and psychological functioning in women with schizophrenia or bipolar ...
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    Scandiatransplant Exchange Program (STEP) : Development and Results From an International Kidney Exchange Program 
    Duus Weinreich, Ilse; Andersson, Tommy; Andrésdóttir, Margrét Birna; Bengtsson, Mats; Biglarnia, Alireza; Bistrup, Claus; Boulland, Line; Bruunsgaard, Helle; Helanterä, Ilkka; Kölvald, Kulli; Lauronen, Jouni; Lindahl, Jørn Petter; Skov, Karin; Schwarz Sørensen, Søren; Wennberg, Lars; Lindner, Per (2023-10-16)
    BACKGROUND: Kidney transplant candidates may be incompatible with their intended living donors because of the presence of antibodies against HLA and/or ABO. To increase the possibility of finding an acceptable kidney donor for these patients, the ...
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    A survey of preferences for respiratory support in the intensive care unit for patients with acute hypoxaemic respiratory failure 
    Aslam, Tayyba N.; Klitgaard, Thomas L.; Ahlstedt, Christian A.O.; Andersen, Finn H.; Chew, Michelle S.; Collet, Marie O.; Cronhjort, Maria; Estrup, Stine; Fossum, Ole K.; Frisvold, Shirin K.; Gillmann, Hans Joerg; Granholm, Anders; Gundem, Trine M.; Hauss, Kristin; Hollenberg, Jacob; Huanca Condori, Maria E.; Hästbacka, Johanna; Johnstad, Bror A.; Keus, Eric; Kjær, Maj Brit N.; Klepstad, Pål; Krag, Mette; Kvåle, Reidar; Malbrain, Manu L.N.G.; Meyhoff, Christian S.; Morgan, Matt; Møller, Anders; Pfortmueller, Carmen A.; Poulsen, Lone M.; Robertson, Andrew C.; Schefold, Joerg C.; Schjørring, Olav L.; Siegemund, Martin; Sigurðsson, Martin Ingi; Sjövall, Fredrik; Strand, Kristian; Stueber, Thomas; Szczeklik, Wojciech; Wahlin, Rebecka R.; Wangberg, Helge L.; Wian, Karl Andre; Wichmann, Sine; Hofsø, Kristin; Møller, Morten H.; Perner, Anders; Rasmussen, Bodil S.; Laake, Jon H. (2023-11)
    Background: When caring for mechanically ventilated adults with acute hypoxaemic respiratory failure (AHRF), clinicians are faced with an uncertain choice between ventilator modes allowing for spontaneous breaths or ventilation fully controlled by the ...
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    Therapists' beliefs about excessive reassurance seeking and helping manage it : Does experience play a role? 
    Halldórsson, Brynjar; Salkovskis, Paul M. (2023-09-13)
    Excessive reassurance seeking (ERS) is believed to play an important role in maintaining mental health problems, in particular anxiety disorders such as obsessive-compulsive disorder and health anxiety. Despite this, therapists commonly give into ...
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    sEMG Spectral Analysis and Machine Learning Algorithms Are Able to Discriminate Biomechanical Risk Classes Associated with Manual Material Liftings 
    Donisi, Leandro; Jacob, Deborah; Guerrini, Lorena; Prisco, Giuseppe; Esposito, Fabrizio; Cesarelli, Mario; Amato, Francesco; Gargiulo, Paolo (2023-09-20)
    Manual material handling and load lifting are activities that can cause work-related musculoskeletal disorders. For this reason, the National Institute for Occupational Safety and Health proposed an equation depending on the following parameters: ...
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    Changes in disease-related knowledge and educational needs of patients with coronary heart disease over a six-month period between hospital discharge and follow-up 
    Svavarsdóttir, Margrét Hrönn; Halapi, Eva Charlotte; Ketilsdóttir, Auður; Ólafsdóttir, Inga Valborg; Ingadóttir, Brynja (2023-12)
    Objective: To describe changes in the disease-related knowledge and educational needs of individuals with coronary heart disease (CHD). Methods: Patients hospitalized for CHD answered questionnaires about disease-related knowledge (Coronary Artery ...
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    A multidisciplinary evaluation, exploration, and advancement of the concept of a traumatic birth experience 
    Kuipers, Yvonne; Thomson, Gill; Škodová, Zuzana; Bozic, Ina; Sigurðardóttir, Valgerður Lísa; Goberna-Tricas, Josefina; Zurera, Alba; Neves, Dulce Morgado; Barata, Catarina; Klier, Claudia (2024-02)
    Background: Understanding a woman's traumatic birth experience benefits from an approach that considers perspectives from various fields of healthcare and social sciences. Aim: To evaluate and explore the multidisciplinary perspectives surrounding a ...
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    Rauðkyrningabólga í vélinda í börnum - tvö sjúkratilfelli 
    Sigurdsson, Lúther; Agnarsson, Úlfur; Axelsson, Ari Víðir (2013-12)
    Ágrip Rauðkyrningabólga í vélinda er tiltölulega nýr sjúkdómur, fyrst lýst 1978, en hefur hlotið aukna athygli síðastliðinn áratug. Í fyrstu aðallega í börnum og unglingum en síðan einnig í fullorðnum. Í yngri börnum eru vanþrif og uppköst aðaleinkenni ...
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    Sequence variant affects GCSAML splicing, mast cell specific proteins, and risk of urticaria 
    Kristjansson, Ragnar P.; Oskarsson, Gudjon R.; Skuladottir, Astros; Oddsson, Asmundur; Rognvaldsson, Solvi; Sveinbjornsson, Gardar; Lund, Sigrun H.; Jensson, Brynjar O.; Styrmisdottir, Edda L.; Halldorsson, Gisli H.; Ferkingstad, Egil; Eldjarn, Grimur Hjorleifsson; Beyter, Doruk; Kristmundsdottir, Snædis; Juliusson, Kristinn; Fridriksdottir, Run; Arnadottir, Gudny A.; Katrinardottir, Hildigunnur; Snorradottir, Margret H.; Tragante, Vinicius; Stefansdottir, Lilja; Ivarsdottir, Erna V.; Bjornsdottir, Gyda; Halldorsson, Bjarni V.; Thorleifsson, Gudmar; Lúðvíksson, Björn Rúnar; Önundarson, Páll Torfi; Sævarsdóttir, Sædís; Melsted, Pall; Norddahl, Gudmundur L.; Björnsdóttir, Unnur Steina; Olafsdottir, Thorunn; Gudbjartsson, Daniel F.; Thorsteinsdottir, Unnur; Jonsdottir, Ingileif; Sulem, Patrick; Stefansson, Kari (2023-07-10)
    Urticaria is a skin disorder characterized by outbreaks of raised pruritic wheals. In order to identify sequence variants associated with urticaria, we performed a meta-analysis of genome-wide association studies for urticaria with a total of 40,694 ...