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The Effectiveness of Percutaneous Vertebroplasty is Determined by the Patient-Specific Bone Condition and the Treatment Strategy

The Effectiveness of Percutaneous Vertebroplasty is Determined by the Patient-Specific Bone Condition and the Treatment Strategy


Titill: The Effectiveness of Percutaneous Vertebroplasty is Determined by the Patient-Specific Bone Condition and the Treatment Strategy
Höfundur: Widmer Soyka, René P.
Helgason, Benedikt
Hazrati Marangalou, Javad
van den Bergh, Joop P.
Rietbergen, Bert van
Ferguson, Stephen J.
Útgáfa: 2016-04-21
Tungumál: Enska
Umfang: e0151680
Háskóli/Stofnun: Háskólinn í Reykjavík
Reykjavik University
Deild: Tækni- og verkfræðideild (HR)
School of Science and Engineering (RU)
Birtist í: PLOS ONE;11(4)
ISSN: 1932-6203
DOI: doi.org/10.1371/journal.pone.0151680
Efnisorð: Finite element method; Vertebral fractures; Osteoporosis compression fractures; Vertebroplasty; Treatment parameters; Beinþynning; Beinbrot; Meðferð
URI: https://hdl.handle.net/20.500.11815/882

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Tilvitnun:

Widmer Soyka RP, Helgason B, Hazrati Marangalou J, van den Bergh JP, Rietbergen Bv, Ferguson SJ (2016) The Effectiveness of Percutaneous Vertebroplasty Is Determined by the Patient-Specific Bone Condition and the Treatment Strategy. PLoS ONE 11(4): e0151680. doi:10.1371/ journal.pone.0151680

Útdráttur:

Vertebral fragility fractures are often treated by injecting bone cement into the collapsed vertebral bodies (vertebroplasty). The mechanisms by which vertebroplasty induces pain relief are not completely understood yet and recent debates cast doubt over the outcome of the procedure. The controversy is intensified by inconsistent results of randomized clinical trials and biomechanical studies that have investigated the effectiveness or the change in bio-mechanical response due to the reinforcement. The purpose of this study was to evaluate the effectiveness of vertebroplasty, by varying the relevant treatment parameters and (a) computationally predicting the improvement of the fracture risk depending on the chosen treatment strategy, and (b) identifying the determinants of a successful treatment.

Leyfi:

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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