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Fletta eftir efnisorði "TFEB"

Fletta eftir efnisorði "TFEB"

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    MITF and TFEB cross-regulation in melanoma cells 
    Ballesteros Alvarez, Josue; Dilshat, Ramile; Fock, Valerie; Möller, Katrin; Karl, Ludwig; LARUE, Lionel; Ogmundsdottir, Margret H; Steingrimsson, Eirikur (Public Library of Science (PLoS), 2020-09-03)
    The MITF, TFEB, TFE3 and TFEC (MiT-TFE) proteins belong to the basic helix-loop-helix family of leucine zipper transcription factors. MITF is crucial for melanocyte development and differentiation, and has been termed a lineage-specific oncogene in ...
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    Mitf is a master regulator of the v-ATPase, forming a control module for cellular homeostasis with v-ATPase and TORC1 
    Zhang, T.; Zhou, Q.; Ogmundsdottir, Margret H; Möller, Katrin; Siddaway, R.; Larue, L.; Hsing, M.; Kong, S. W.; Goding, C. R.; Palsson, Arnar; Steingrimsson, Eirikur; Pignoni, F. (The Company of Biologists, 2015-06-19)
    The v-ATPase is a fundamental eukaryotic enzyme that is central to cellular homeostasis. Although its impact on key metabolic regulators such as TORC1 is well documented, our knowledge of mechanisms that regulate v-ATPase activity is limited. Here, we ...