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Browsing Háskóli Íslands by Subject "Cyclodextrins"
Now showing items 1-6 of 6
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(University of Iceland, School of Health Sciences, Faculty of Pharmaceutical Sciences, 2022-02)Sýklódextrín eru hjálparefni sem notuð eru lyfjaform svo sem vatnslausnir (t.d. stungulyf) og föst lyfjaform (t.d. töflur), til að auka leysanleika, stöðugleika og aðgengi lyfjanna. Í þessu verkefni var notkun sýklódextrína sem hjálparefni í augndropum ... -
(MDPI AG, 2019-05-15)Natamycin is the only drug approved for fungal keratitis treatment, but its low water solubility and low ocular penetration limit its efficacy. The purpose of this study was to overcome these limitations by encapsulating the drug in single or mixed ...
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(American Chemical Society (ACS), 2019-01-16)A detailed comprehensive study on how the formation of soluble and insoluble carbamazepine/cyclodextrins (CBZ/CD) complexes (with consequent changes in the solid-phase composition) depends on the CD structure is not yet available. Moreover, the study ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2022-11-01)Fyrir marga lyfjaflokka þykir staðbundin lyfjagjöf í augndropaformi ákjósanlegasta leiðin vegna einfaldleika við lyfjagjöf. Eru augndropar algengasta aðferðin til að meðhöndla augnsjúkdóma í fremri hluta augans. Staðbundin lyfjagjöf í augndropaformi ...
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(Elsevier, 2020)Tacrolimus is a macrolide lactone and potent immunosuppressant. It is highly lipophilic and has very limited aqueous solubility. Tacrolimus is highly susceptible to hydrolysis which results in very limited stability in aqueous solutions. Besides this, ...
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(Elsevier, 2022-01)Difluprednate is a synthetic glucocorticoid used for the treatment of postoperative inflammation and pain associated with endogenous uveitis. It is very lipophilic with limited aqueous solubility and stability. The only available marketed formulation ...
Now showing items 1-6 of 6