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Fletta eftir deild "Faculty of Medicine"

Fletta eftir deild "Faculty of Medicine"

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    Aminopeptidase expression in multiple myeloma associates with disease progression and sensitivity to melflufen 
    Miettinen, Juho J.; Kumari, Romika; Traustadóttir, Gunnhildur Ásta; Huppunen, Maiju Emilia; Sergeev, Philipp; Majumder, Muntasir M.; Schepsky, Alexander; Guðjónsson, Þórarinn; Lievonen, Juha; Bazou, Despina; Dowling, Paul; O‘gorman, Peter; Slipicevic, Ana; Anttila, Pekka; Silvennoinen, Raija; Nupponen, Nina N.; Lehmann, Fredrik; Heckman, Caroline A. (2021-03-26)
    Multiple myeloma (MM) is characterized by extensive immunoglobulin production leading to an excessive load on protein homeostasis in tumor cells. Aminopeptidases contribute to proteolysis by catalyzing the hydrolysis of amino acids from proteins or ...
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    Antibacterial properties of poly (N,N-dimethylaminoethyl methacrylate) obtained at different initiator concentrations in solution polymerization 
    Stawski, Dawid; Rolińska, Karolina; Zielińska, Dorota; Sahariah, Priyanka; Hjálmarsdóttir, Martha A.; Másson, Már (2022-01-01)
    The samples of poly(N,N-dimethylaminoethyl methacrylate) were synthesized by radical polymerization. The amount of monomer and solvent was constant as opposed to an amount of initiator which was changing. No clear relationship between polymerization ...
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    Antibiotic resistance among major pathogens compared to hospital treatment guidelines and antibiotic use in Nordic hospitals 2010–2018 
    Möller, Vidar; Östholm-Balkhed, Åse; Berild, Dag; Fredriksson, Mats; Gottfreðsson, Magnús; Holmbom, Martin; Järvinen, Asko; Kristjánsson, Már; Rydell, Ulf; Sönksen, Ute Wolff; Kolmos, Hans Joern; Hanberger, Håkan (2021-05-10)
    BACKGROUND: The Nordic countries have comparable nationwide antibiotic resistance surveillance systems and individual antibiotic stewardship programmes. The aim of this study was to assess antibiotic resistance among major pathogens in relation to ...
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    Antibodies to a Citrullinated Porphyromonas gingivalis Epitope Are Increased in Early Rheumatoid Arthritis, and Can Be Produced by Gingival Tissue B Cells : Implications for a Bacterial Origin in RA Etiology 
    Sherina, Natalia; de Vries, Charlotte; Kharlamova, Nastya; Sippl, Natalie; Jiang, Xia; Brynedal, Boel; Kindstedt, Elin; Hansson, Monika; Mathsson-Alm, Linda; Israelsson, Lena; Stålesen, Ragnhild; Saevarsdottir, Saedis; Holmdahl, Rikard; Hensvold, Aase; Johannsen, Gunnar; Eriksson, Kaja; Sallusto, Federica; Catrina, Anca I.; Rönnelid, Johan; Grönwall, Caroline; Yucel-Lindberg, Tülay; Alfredsson, Lars; Klareskog, Lars; Piccoli, Luca; Malmström, Vivianne; Amara, Khaled; Lundberg, Karin (2022-04-20)
    Based on the epidemiological link between periodontitis and rheumatoid arthritis (RA), and the unique feature of the periodontal bacterium Porphyromonas gingivalis to citrullinate proteins, it has been suggested that production of anti-citrullinated ...
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    Antihypertensive medication uses and serum ACE2 levels 
    Emilsson, Valur; Gudmundsson, Elias F.; Aspelund, Thor; Jonsson, Brynjolfur G.; Gudjonsson, Alexander; Launer, Lenore J.; Jennings, Lori L.; Gudmundsdottir, Valborg; Gudnason, Vilmundur (2020-05-25)
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    Antipsychotic use in pregnancy and risk of attention/deficit-hyperactivity disorder and autism spectrum disorder : a Nordic cohort study 
    Hálfdánarson, Óskar; Cohen, Jacqueline M.; Karlstad, Øystein; Cesta, Carolyn E.; Bjørk, Marte Helene; Håberg, Siri Eldevik; Einarsdóttir, Kristjana; Furu, Kari; Gissler, Mika; Hjellvik, Vidar; Kieler, Helle; Leinonen, Maarit K.; Nørgaard, Mette; Öztürk Essen, Buket; Ulrichsen, Sinna Pilgaard; Reutfors, Johan; Zoega, Helga (2022-05-01)
    BACKGROUND: Antipsychotics are increasingly used among women of childbearing age and during pregnancy. OBJECTIVE: To determine whether children exposed to antipsychotics in utero are at increased risk of attention-deficit/hyperactivity disorder (ADHD) ...
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    Appraisals of Social Trauma and Their Role in the Development of Post-Traumatic Stress Disorder and Social Anxiety Disorder 
    Harðarson, Jóhann Pálmar; Guðmundsdóttir, Berglind; Valdimarsdottir, Audur G; Gudmundsdottir, Karen; Tryggvadottir, Arnrun; Thorarinsdottir, Kristjana; Wessman, Inga Dröfn; Davidsdottir, Soley; Tómasson, Gunnar; Holmes, Emily A; Thorisdottir, Audur S; Bjornsson, Andri S (2023-07-11)
    Cognitive theories of post-traumatic stress disorder (PTSD) feature appraisal of trauma as a critical factor in the development and maintenance of the disorder. Here we explored appraisals of social trauma (severe rejection or humiliation). Participants ...
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    Argininosuccinate lyase is a metabolic vulnerability in breast development and cancer 
    Karvelsson, Sigurður Trausti; Wang, Qiong; Hilmarsdóttir, Bylgja; Sigurðsson, Arnar; Moestue, Siver Andreas; Mælandsmo, Gunhild Mari; Halldórsson, Skarphédinn; Guðmundsson, Steinn; Rolfsson, Óttar (2021-09-17)
    Epithelial-to-mesenchymal transition (EMT) is fundamental to both normal tissue development and cancer progression. We hypothesized that EMT plasticity defines a range of metabolic phenotypes and that individual breast epithelial metabolic phenotypes ...
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    Assessing the Involvement of Users During Development of Lower Limb Wearable Robotic Exoskeletons : A Survey Study 
    Ármannsdóttir, Anna L.; Beckerle, Philipp; Moreno, Juan C.; van Asseldonk, Edwin H.F.; Manrique-Sancho, Maria Teresa; del-Ama, Antonio J.; Veneman, Jan F.; Briem, Kristín (2020-05-01)
    Objective: To explore user-centered design methods currently implemented during development of lower limb wearable robots and how they are utilized during different stages of product development. Background: Currently, there appears to be a lack of ...
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    Assessing the Reach, Adoption, Implementation, and Maintenance of the Systems Analysis and Improvement Approach for prevention of mother-to-child transmission of HIV in Manica Province, Mozambique 2018-2021 (the SAIA-SCALE Program) 
    Crocker, J; Ásbjörnsdóttir, K; Coutinho, J; Agostinho, M; Amaral, F; Cruz, E; Cuembelo, F; Dinis, A; Feijão, ET; Fernandes, Q; Gimbel, S; Hazim, C; Inguane, C; Sherr, K (2022-06)
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    Assessing thyroid cancer risk using polygenic risk scores 
    Liyanarachchi, Sandya; Gudmundsson, Julius; Ferkingstad, Egil; He, Huiling; Jónasson, Jón Gunnlaugur; Tragante, Vinicius; Asselbergs, Folkert W.; Xu, Li; Kiemeney, Lambertus A.; Netea-Maier, Romana T.; Mayordomo, Jose I.; Plantinga, Theo S.; Hjartarson, Hannes; Hrafnkelsson, Jón; Sturgis, Erich M.; Brock, Pamela; Nabhan, Fadi; Thorleifsson, Gudmar; Ringel, Matthew D.; Stefansson, Kari; de la Chapelle, Albert (2020-03-17)
    Genome-wide association studies (GWASs) have identified at least 10 single-nucleotide polymorphisms (SNPs) associated with papillary thyroid cancer (PTC) risk. Most of these SNPs are common variants with small to moderate effect sizes. Here we assessed ...
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    Assessment of kidney function : clinical indications for measured GFR 
    Ebert, Natalie; Bevc, Sebastjan; Bökenkamp, Arend; Gaillard, Francois; Hornum, Mads; Jager, Kitty J.; Mariat, Christophe; Eriksen, Bjørn Odvar; Palsson, Runolfur; Rule, Andrew D.; van Londen, Marco; White, Christine; Schaeffner, Elke (2021-08-01)
    In the vast majority of cases, glomerular filtration rate (GFR) is estimated using serum creatinine, which is highly influenced by age, sex, muscle mass, body composition, severe chronic illness and many other factors. This often leads to misclassification ...
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    Assessment of Posttraumatic Stress Disorder and Educational Achievement in Sweden 
    Vilaplana-Pérez, Alba; Sidorchuk, Anna; Pérez-Vigil, Ana; Brander, Gustaf; Isoumura, Kayoko; Hesselmark, Eva; Sevilla-Cermeño, Laura; Valdimarsdóttir, Unnur Anna; Song, Huan; Jangmo, Andreas; Kuja-Halkola, Ralf; D'Onofrio, Brian M.; Larsson, Henrik; Garcia-Soriano, Gemma; Mataix-Cols, David; Fernández de la Cruz, Lorena (2020-12-01)
    Importance: Posttraumatic stress disorder (PTSD) has been associated with impaired educational performance. Previous studies on the disorder could not control for important measured and unmeasured confounders. Objective: To prospectively investigate ...
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    Association between abdominal and general obesity and respiratory symptoms, asthma and COPD. Results from the RHINE study 
    Kisiel, Marta A; Arnfelt, Oscar; Lindberg, Eva; Jogi, Oscar; Malinovschi, Andrei; Johannessen, Ane; Benediktsdóttir, Bryndís; Franklin, Karl; Holm, Mathias; Real, Francisco Gomez; Sigsgaard, Torben; Gíslason, Þórarinn; Modig, Lars; Janson, Christer (2023-05)
    INTRODUCTION: Previous studies on the association between abdominal and general obesity and respiratory disease have provided conflicting results. AIMS AND OBJECTIVES: We aimed to explore the associations of abdominal obesity with respiratory symptoms, ...
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    Association between Adverse Childhood Experiences and Multiple Sclerosis in Icelandic Women-A Population-Based Cohort Study 
    Gatto, Nicole M; Þórðardóttir, Edda Björk; Tómasson, Gunnar; Rúnarsdóttir, Harpa; Song, Huan; Jakobsdóttir, Jóhanna; Aspelund, Thor; Valdimarsdóttir, Unnur Anna; Hauksdóttir, Arna (2022-11-16)
    BACKGROUND: A growing literature, mostly based on selected populations, indicates that traumas may be associated with autoimmune diseases, yet few studies exist on adverse childhood experiences (ACEs) and multiple sclerosis (MS) in the general population. ...
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    Association between adverse childhood experiences and premenstrual disorders : a cross-sectional analysis of 11,973 women 
    Yang, Qian; Þórðardóttir, Edda Björk; Hauksdóttir, Arna; Aspelund, Thor; Jakobsdóttir, Jóhanna; Halldorsdottir, Thorhildur; Tómasson, Gunnar; Rúnarsdóttir, Harpa; Daníelsdóttir, Hilda Björk; Bertone-Johnson, Elizabeth R; Sjölander, Arvid; Fang, Fang; Lu, Donghao; Valdimarsdóttir, Unnur Anna (2022-02-21)
    Background: Childhood abuse and neglect have been associated with premenstrual disorders (PMDs), including premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD). However, the associations of other adverse childhood experiences (ACEs) ...
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    Association between Childhood Body Size and Premenstrual Disorders in Young Adulthood 
    Lu, Donghao; Aleknaviciute, Jurate; Kamperman, Astrid M.; Tamimi, Rulla M.; Ludvigsson, Jonas F.; Valdimarsdóttir, Unnur A.; Bertone-Johnson, Elizabeth R. (2022-03-01)
    Importance: Emerging data suggest that more than two-thirds of premenstrual disorders (PMDs), including premenstrual syndrome and premenstrual dysphoric disorder, have symptom onset during the teen years. Adulthood adiposity has been associated with ...
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    ASSOCIATION BETWEEN GRIP STRENGTH AND COGNITIVE FUNCTION AMONG COMMUNITY-DWELLING OLDER ADULTS. 
    Chang, M; Ramel, A; Jonsson, PV; Thorsdottir, I; Geirsdottir, O (2019-11)
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    Association between service readiness and PMTCT cascade effectiveness : a 2018 cross-sectional analysis from Manica province, Mozambique 
    Dinis, Aneth; Augusto, Orvalho; Ásbjörnsdóttir, Kristjana H.; Crocker, Jonny; Gimbel, Sarah; Inguane, Celso; Ramiro, Isaías; Coutinho, Joana; Agostinho, Mery; Cruz, Emilia; Amaral, Fernando; Tavede, Esperança; Isidoro, Xavier; Sidat, Yaesh; Nassiaca, Regina; Murgorgo, Filipe; Cuembelo, Fátima; Hazim, Carmen E.; Sherr, Kenneth (2022-11-28)
    Background: Despite high coverage of maternal and child health services in Mozambique, prevention of mother-to-child transmission of HIV (PMTCT) cascade outcomes remain sub-optimal. Delivery effectiveness is modified by health system preparedness. ...
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    Association of common genetic variants with brain microbleeds : A genome-wide association study 
    Alzheimer's Disease Neuroimaging Initiative (2020-12-15)
    OBJECTIVE: To identify common genetic variants associated with the presence of brain microbleeds (BMBs). METHODS: We performed genome-wide association studies in 11 population-based cohort studies and 3 case-control or case-only stroke cohorts. Genotypes ...