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Browsing IRIS by Subject "Ónæmisfræði"

Browsing IRIS by Subject "Ónæmisfræði"

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    The adjuvants dmLT and mmCT enhance humoral immune responses to a pneumococcal conjugate vaccine after both parenteral or mucosal immunization of neonatal mice 
    Molina Estupiñan, Jenny Lorena; Pind, Auður Anna Aradóttir; Pajoohian, Poorya Foroutan; Jónsdóttir, Ingileif; Bjarnarson, Stefanía P (2023-01-20)
    Immaturity of the neonatal immune system contributes to increased susceptibility to infectious diseases and poor vaccine responses. Therefore, better strategies for early life vaccination are needed. Adjuvants can enhance the magnitude and duration of ...
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    Anomaly detection in sleep : detecting mouth breathing in children 
    Biedebach, Luka; Óskarsdóttir, María; Arnardóttir, Erna Sif; Sigurdardóttir, Sigridur Erla; Clausen, Michael Valur; Sigurðardóttir, Sigurveig Þ; Serwatko, Marta; Islind, Anna Sigríður (2023-11-13)
    Identifying mouth breathing during sleep in a reliable, non-invasive way is challenging and currently not included in sleep studies. However, it has a high clinical relevance in pediatrics, as it can negatively impact the physical and mental health of ...
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    ASIA-heilkenni - tengsl við silíkon 
    Sigurðardóttir, Sigurveig Þ; Sigurjonsson, Hannes; Thorarinsson, Andri Mar; Erlendsson, Kristján (2023-04)
    Ágrip Áratugum saman hafa ýmsir möguleikar verið nýttir til að bæta líðan, starfsemi og útlit manna með íhlutum, ígræddum með skurðaðgerðum. Silíkonpúðar hafa verið notaðir frá miðri síðustu öld til enduruppbyggingar á brjóstum, til dæmis eftir ...
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    Continuous increase of immunoglobulin therapy in Iceland 
    Runólfsson, Valgeir Steinn; Lúðvíksson, Björn Rúnar; Einarsdóttir, Rannveig Alma; Óskarsdóttir, Þórunn; Thors, Valtýr Stefánsson; Haraldsson, Ásgeir (2022-12)
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    Deep learning-based algorithm accurately classifies sleep stages in preadolescent children with sleep-disordered breathing symptoms and age-matched controls 
    Somaskandhan, Pranavan; Leppänen, Timo; Terrill, Philip I; Sigurdardottir, Sigridur; Arnardóttir, Erna Sif; Ólafsdóttir, Kristín Anna; Serwatko, Marta; Sigurðardóttir, Sigurveig Þ; Clausen, Michael Valur; Töyräs, Juha; Korkalainen, Henri (2023-04-14)
    INTRODUCTION: Visual sleep scoring has several shortcomings, including inter-scorer inconsistency, which may adversely affect diagnostic decision-making. Although automatic sleep staging in adults has been extensively studied, it is uncertain whether ...
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    Factor D Inhibition Blocks Complement Activation Induced by Mutant Factor B Associated With Atypical Hemolytic Uremic Syndrome and Membranoproliferative Glomerulonephritis 
    Aradottir, Sigridur Sunna; Kristoffersson, Ann Charlotte; Roumenina, Lubka T.; Bjerre, Anna; Kashioulis, Pavlos; Pálsson, Runólfur; Karpman, Diana (2021-06-10)
    Complement factor B (FB) mutant variants are associated with excessive complement activation in kidney diseases such as atypical hemolytic uremic syndrome (aHUS), C3 glomerulopathy and membranoproliferative glomerulonephritis (MPGN). Patients with aHUS ...
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    Fyrsta meðferð með tocilizumab við COVID-19 hérlendis - sjúkratilfelli 
    Björnsson, Aron Hjalti; Ólafsdóttir, Þorbjörg; Þormar, Katrín María; Kristjánsson, Már; Þórisdóttir, Anna Sesselja; Lúðvíksson, Björn Rúnar; Gudmundsson, Sigurdur; Gottfreðsson, Magnús (2020-05-06)
    Rúmlega fimmtugur karlmaður sem hafði verið á ferðalagi erlendis veiktist við komuna til landsins með flensulíkum einkennum og greindist með COVID-19. Nokkrum dögum síðar versnandi honum af öndunarfæraeinkennum og lagðist inn á Landspítala. Hann reyndist ...
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    Genome-wide association study of circulating interleukin 6 levels identifies novel loci 
    Ahluwalia, Tarunveer S.; Prins, Bram P.; Abdollahi, Mohammadreza; Armstrong, Nicola J.; Aslibekyan, Stella; Bain, Lisa; Jefferis, Barbara; Baumert, Jens; Beekman, Marian; Ben-Shlomo, Yoav; Bis, Joshua C.; Mitchell, Braxton D.; De Geus, Eco; Delgado, Graciela E.; Marek, Diana; Eriksson, Joel; Kajantie, Eero; Kanoni, Stavroula; Kemp, John P.; Lu, Chen; Marioni, Riccardo E.; McLachlan, Stela; Milaneschi, Yuri; Nolte, Ilja M.; Petrelis, Alexandros M.; Porcu, Eleonora; Sabater-Lleal, Maria; Naderi, Elnaz; Seppälä, Ilkka; Shah, Tina; Singhal, Gaurav; Standl, Marie; Teumer, Alexander; Thalamuthu, Anbupalam; Thiering, Elisabeth; Trompet, Stella; Ballantyne, Christie M.; Benjamin, Emelia J.; Casas, Juan P.; Toben, Catherine; Dedoussis, George; Deelen, Joris; Durda, Peter; Engmann, Jorgen; Feitosa, Mary F.; Grallert, Harald; Hammarstedt, Ann; Harris, Sarah E.; Homuth, Georg; Guðnason, Vilmundur G. (2021-01-30)
    Interleukin 6 (IL-6) is a multifunctional cytokine with both pro-A nd anti-inflammatory properties with a heritability estimate of up to 61%. The circulating levels of IL-6 in blood have been associated with an increased risk of complex disease ...
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    Meals, Microbiota and Mental Health in Children and Adolescents (MMM-Study) : A protocol for an observational longitudinal case-control study 
    Asbjornsdottir, Birna; Lauth, Bertrand; Fasano, Alessio; Thorsdottir, Inga; Karlsdottir, Ingibjorg; Gudmundsson, Larus S.; Gottfredsson, Magnus; Smarason, Orri; Sigurðardóttir, Sigurveig Þ; Halldorsson, Thorhallur I.; Marteinsson, Viggo Thor; Gudmundsdottir, Valborg; Birgisdottir, Bryndis Eva (2022-09-01)
    Recent studies indicate that the interplay between diet, intestinal microbiota composition, and intestinal permeability can impact mental health. More than 10% of children and adolescents in Iceland suffer from mental disorders, and rates of psychotropics ...
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    Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset 
    Sævarsdóttir, Sædís; Stefansdottir, Lilja; Sulem, P.; Thorleifsson, G.; Ferkingstad, E.; Rutsdottir, G.; Glintborg, B.; Westerlind, H.; Gröndal, Gerður María; Loft, I.C.; Sorensen, S.B.; Lie, B.A.; Brink, M.; Arlestig, L.; Arnthorsson, A.O.; Baecklund, E.; Banasik, K.; Bank, S.; Bjorkman, L.I.; Ellingsen, T.; Erikstrup, C.; Frei, O.; Gjertsson, I.; Gudbjartsson, D.F.; Gudjonsson, S.A.; Halldorsson, G.H.; Hendricks, O.; Hillert, J.; Hogdall, E.; Jacobsen, Sø; Jensen, D.V.; Jonsson, Helgi; Kastbom, A.; Kockum, I.; Kristensen, S.; Kristjansdottir, Helga; Larsen, M.H.; Linauskas, A.; Hauge, E.-M.; Loft, A.G.; Lúðvíksson, Björn Rúnar; Lund, S.H.; Markusson, Þorsteinn; Masson, G.; Melsted, P.; Moore, K.H.S.; Munk, H.; Nielsen, K.R.; Norddahl, G.L.; Oddsson, A.; Olafsdottir, T.A.; Olason, P.I.; Olsson, T.; Ostrowski, S.R.; Hørslev-Petersen, K.; Rognvaldsson, S.; Sanner, H.; Silberberg, G.N.; Stefansson, H.; Sørensen, E.; Sørensen, I.J.; Turesson, C.; Bergman, T.; Alfredsson, L.; Kvien, T.K.; Brunak, Sø; Steinsson, K.; Andersen, V.; Andreassen, O.A.; Rantapää-Dahlqvist, S.; Hetland, M.L.; Klareskog, L.; Askling, J.; Padyukov, L.; Pedersen, O.B.V.; Thorsteinsdottir, U.; Jonsdottir, I.; Stefánsson, Kári (2022-04-25)
    Objectives To find causal genes for rheumatoid arthritis (RA) and its seropositive (RF and/or ACPA positive) and seronegative subsets. Methods We performed a genome-wide association study (GWAS) of 31 313 RA cases (68% seropositive) and ∼1 million ...
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    Normal neonatal TREC and KREC levels in early onset juvenile idiopathic arthritis 
    Guðmundsdóttir, Judith Amalía; Thorgeirsdottir, Sigridur; Lundbäck, Veroniqa; Göngrich, Christina; Lingman Framme, Jenny; Kindgren, Erik; Rydenman, Karin; Lúðvíksson, Björn Rúnar; Bjarnadóttir, Helga; Runarsdottir, Saga; Nilsson, Staffan; Zetterström, Rolf H.; Ekwall, Olov; Lindgren, Susanne (2023-04)
    Objective: Dysregulated central tolerance predisposes to autoimmune diseases. Reduced thymic output as well as compromised central B cell tolerance checkpoints have been proposed in the pathogenesis of juvenile idiopathic arthritis (JIA). The aim of ...
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    Rauðkyrningabólga í vélinda í börnum - tvö sjúkratilfelli 
    Sigurdsson, Lúther; Agnarsson, Úlfur; Axelsson, Ari Víðir (2013-12)
    Ágrip Rauðkyrningabólga í vélinda er tiltölulega nýr sjúkdómur, fyrst lýst 1978, en hefur hlotið aukna athygli síðastliðinn áratug. Í fyrstu aðallega í börnum og unglingum en síðan einnig í fullorðnum. Í yngri börnum eru vanþrif og uppköst aðaleinkenni ...
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    Sequence variant affects GCSAML splicing, mast cell specific proteins, and risk of urticaria 
    Kristjansson, Ragnar P.; Oskarsson, Gudjon R.; Skuladottir, Astros; Oddsson, Asmundur; Rognvaldsson, Solvi; Sveinbjornsson, Gardar; Lund, Sigrun H.; Jensson, Brynjar O.; Styrmisdottir, Edda L.; Halldorsson, Gisli H.; Ferkingstad, Egil; Eldjarn, Grimur Hjorleifsson; Beyter, Doruk; Kristmundsdottir, Snædis; Juliusson, Kristinn; Fridriksdottir, Run; Arnadottir, Gudny A.; Katrinardottir, Hildigunnur; Snorradottir, Margret H.; Tragante, Vinicius; Stefansdottir, Lilja; Ivarsdottir, Erna V.; Bjornsdottir, Gyda; Halldorsson, Bjarni V.; Thorleifsson, Gudmar; Lúðvíksson, Björn Rúnar; Önundarson, Páll Torfi; Sævarsdóttir, Sædís; Melsted, Pall; Norddahl, Gudmundur L.; Björnsdóttir, Unnur Steina; Olafsdottir, Thorunn; Gudbjartsson, Daniel F.; Thorsteinsdottir, Unnur; Jonsdottir, Ingileif; Sulem, Patrick; Stefansson, Kari (2023-07-10)
    Urticaria is a skin disorder characterized by outbreaks of raised pruritic wheals. In order to identify sequence variants associated with urticaria, we performed a meta-analysis of genome-wide association studies for urticaria with a total of 40,694 ...