dc.contributor |
Háskóli Íslands |
dc.contributor |
University of Iceland |
dc.contributor.author |
Bock, David |
dc.contributor.author |
Angenete, Eva |
dc.contributor.author |
Asplund, Dan |
dc.contributor.author |
Bjartell, Anders |
dc.contributor.author |
Carlsson, Stefan |
dc.contributor.author |
Hugosson, Jonas |
dc.contributor.author |
Stinesen Kollberg, Karin |
dc.contributor.author |
Lantz, Anna |
dc.contributor.author |
Nilsson, Hanna |
dc.contributor.author |
Prytz, Mattias |
dc.contributor.author |
Steineck, Gunnar |
dc.contributor.author |
Thorsteinsdottir, Thordis |
dc.contributor.author |
Wiklund, Peter |
dc.contributor.author |
Haglind, Eva |
dc.date.accessioned |
2021-01-12T15:10:33Z |
dc.date.available |
2021-01-12T15:10:33Z |
dc.date.issued |
2020-04-28 |
dc.identifier.citation |
David Bock, Eva Angenete, Dan Asplund, Anders Bjartell, Stefan Carlsson, Jonas Hugosson, Karin Stinesen Kollberg, Anna Lantz, Hanna Nilsson, Mattias Prytz, Gunnar Steineck, Thordis Thorsteinsdottir, Peter Wiklund & Eva Haglind (2020) Do negative intrusive thoughts at diagnosis predict impaired quality of life, depressed mood and waking up with anxiety 3, 12 and 24 months after radical prostatectomy? – a longitudinal study, Scandinavian Journal of Urology, 54:3, 220-226, DOI: 10.1080/21681805.2020.1754905 |
dc.identifier.issn |
2168-1805 |
dc.identifier.uri |
https://hdl.handle.net/20.500.11815/2353 |
dc.description |
Publisher's version (útgefin grein) |
dc.description.abstract |
Objective: To evaluate the effect of intrusive thoughts at diagnosis on quality of life, depressed mood and waking up with anxiety up to two years after radical prostatectomy. Method: The Laparoscopic Prostatectomy Robot Open (LAPPRO) trial was a prospective, longitudinal multicenter study of 4003 patients undergoing radical prostatectomy. Questionnaire data were collected preoperatively, at 3, 12 and 24 months after surgery. Results: The group of patients with intrusive thoughts at diagnosis had a statistically significant higher postoperative prevalence of impaired quality of life, depressed mood and waking up with anxiety as compared with the group of patients with no or minor intrusive thoughts. The highest risk increase for impaired QoL, depressed mood and waking up with anxiety ≥1/week was at 12, 3 and 3 months, respectively, where the three outcomes increased by 38% (RR: 1.38; 95%CI: 1.27–1.49)), 136% (RR: 2.36; 95%CI: 1.74–3.19)) and 165% (RR: 2.65; 95%CI: 2.22–3.17)), respectively. Conclusions: The demonstrated link between intrusive thoughts and quality of life, depressed mood and waking up with anxiety deliver is further evidence to the idea that intrusive thoughts has potential as an endpoint for assessing and predicting psychological distress among men with prostate cancer diagnosis. Trial registration number: ISRCTN06393679 (www.isrctn.com). Date of registration: 07/02/2008. Retrospectively registered. |
dc.description.sponsorship |
This study was supported by research grants from the Swedish Cancer Society [2008/922, 2010/593, 2016/362], The Swedish Research Council [2012?1770, 2015?02483], ALF grants [138751, 146201 and 4307771, HTA?VGR 6011], the Mrs. Mary von Sydow Foundation, the Anna and Edvin Berger Foundation and the Assar Gabrielsson?s Foundation [FB 18-19]. The authors gratefully acknowledge the participants in the LAPPRO trial. |
dc.format.extent |
220-226 |
dc.language.iso |
en |
dc.publisher |
Informa UK Limited |
dc.relation.ispartofseries |
Scandinavian Journal of Urology;54(3) |
dc.rights |
info:eu-repo/semantics/openAccess |
dc.subject |
Intrusive thoughts |
dc.subject |
Prostate cancer |
dc.subject |
Quality of life |
dc.subject |
Blöðruhálskirtilskrabbamein |
dc.subject |
Þunglyndi |
dc.subject |
Kvíði |
dc.subject |
Lífsgæði |
dc.title |
Do negative intrusive thoughts at diagnosis predict impaired quality of life, depressed mood and waking up with anxiety 3, 12 and 24 months after radical prostatectomy? – a longitudinal study |
dc.type |
info:eu-repo/semantics/article |
dcterms.license |
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use,distribution, and reproduction in any medium, provided the original work is properly cited. |
dc.description.version |
Peer Reviewed |
dc.identifier.journal |
Scandinavian Journal of Urology |
dc.identifier.doi |
10.1080/21681805.2020.1754905 |
dc.relation.url |
https://www.tandfonline.com/doi/pdf/10.1080/21681805.2020.1754905 |
dc.contributor.department |
Hjúkrunarfræðideild (HÍ) |
dc.contributor.department |
Faculty of Nursing (UI) |
dc.contributor.school |
Heilbrigðisvísindasvið (HÍ) |
dc.contributor.school |
School of Health Sciences (UI) |