Noncovalent spin-labeling of RNA: the aptamer approach
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Dagsetning
Höfundar
Journal Title
Journal ISSN
Volume Title
Útgefandi
Royal Society of Chemistry (RSC)
Úrdráttur
In the first example of site-directed spin-labeling of unmodified RNA, a pyrrolidine-nitroxide derivative of tetramethylrosamine (TMR) was shown to bind with high affinity to the malachite green (MG) aptamer, as determined by continuous-wave (CW) electron paramagnetic resonance (EPR), pulsed electron–electron double resonance (PELDOR) and fluorescence spectroscopies.
Lýsing
Post-print (lokagerð höfundar)
Efnisorð
Malachite green, EPR spectroscopy, Isoindoline nitroxides, Distance measurements, Dynamics, Ligands, DNA, Fluorescence, Molecules, Litrófsgreining, Kjarnsýrur, Flúrljómun, DNA-rannsóknir
Citation
Saha, S., Hetzke, T., Prisner, T. F., & Sigurdsson, S. T. (2018). Noncovalent spin-labeling of RNA: The aptamer approach. Chemical Communications, 54(83), 11749-11752. doi:10.1039/c8cc05597a