Opin vísindi

Workplace Diesel Exhausts and Gasoline Exposure and Risk of Colorectal Cancer in Four Nordic Countries

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dc.contributor Háskóli Íslands
dc.contributor University of Iceland
dc.contributor.author Talibov, Madar
dc.contributor.author Sormunen, Jorma
dc.contributor.author Weiderpass, Elisabete
dc.contributor.author Kjaerheim, Kristina
dc.contributor.author Martinsen, Jan-Ivar
dc.contributor.author Sparen, Per
dc.contributor.author Tryggvadottir, Laufey
dc.contributor.author Hansen, Johnni
dc.contributor.author Pukkala, Eero
dc.date.accessioned 2020-04-22T13:31:47Z
dc.date.available 2020-04-22T13:31:47Z
dc.date.issued 2019-06
dc.identifier.citation Talibov, Madar, Jorma Sormunen, Elisabete Weiderpass, Kristina Kjaerheim, Jan-Ivar Martinsen, Per Sparen, Laufey Tryggvadottir, Johnni Hansen, and Eero Pukkala. "Workplace Diesel Exhausts and Gasoline Exposure and Risk of Colorectal Cancer in Four Nordic Countries." Safety and Health at Work 10, no. 2 (2019): 141-50.
dc.identifier.issn 2093-7911
dc.identifier.uri https://hdl.handle.net/20.500.11815/1738
dc.description Publisher's version (útgefin grein)
dc.description.abstract Background: Evidence on associations between occupational diesel exhaust and gasoline exposure and colorectal cancer is limited. We aimed to assess the effect of workplace exposure to diesel exhaust and gasoline on the risk of colorectal cancer. Methods: This case–control study included 181,709 colon cancer and 109,227 rectal cancer cases diagnosed between 1961 and 2005 in Finland, Iceland, Norway, and Sweden. Cases and controls were identified from the Nordic Occupational Cancer Study cohort and matched for country, birth year, and sex. Diesel exhaust and gasoline exposure values were assigned by country-specific job-exposure matrices. Odds ratios and 95% confidence intervals were calculated by using conditional logistic regression models. The results were adjusted for physical strain at work and occupational exposure to benzene, formaldehyde, ionizing radiation, chlorinated hydrocarbons, chromium, and wood dust. Results: Diesel exhaust exposure was associated with a small increase in the risk of rectal cancer (odds ratio = 1.05, 95% confidence interval 1.02-1.08). Gasoline exposure was not associated with colorectal cancer risk. Conclusion: This study showed a small risk increase for rectal cancer after workplace diesel exhaust exposure. However, this finding could be due to chance, given the limitations of the study.
dc.description.sponsorship The authors thank the Nordic Occupational Cancer Studies (NOCCA) project members for the development of NOCCA cohort data and job-exposure matrix.
dc.format.extent 141-150
dc.language.iso en
dc.publisher Elsevier BV
dc.relation.ispartofseries Safety and Health at Work;10(2)
dc.rights info:eu-repo/semantics/openAccess
dc.subject Case–control study
dc.subject Colorectal cancer
dc.subject Diesel exhaust
dc.subject Gasoline
dc.subject Workplace
dc.subject Vinnustaðir
dc.subject Olíumengun
dc.subject Ristilkrabbamein
dc.title Workplace Diesel Exhausts and Gasoline Exposure and Risk of Colorectal Cancer in Four Nordic Countries
dc.type info:eu-repo/semantics/article
dcterms.license This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
dc.description.version Peer Reviewed
dc.identifier.journal Safety and Health at Work
dc.identifier.doi 10.1016/j.shaw.2019.01.001
dc.contributor.department Læknadeild (HÍ)
dc.contributor.department Faculty of Medicine (UI)
dc.contributor.school Heilbrigðisvísindasvið (HÍ)
dc.contributor.school School of Health Sciences (UI)

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