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Fletta eftir deild "Faculty of Industrial Engineering, Mechanical Engineering and Computer Science"
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Fletta eftir deild "Faculty of Industrial Engineering, Mechanical Engineering and Computer Science"
Atriði 1-20 af 26
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(2024-06)This paper explores the potential of large language models, specifically ChatGPT, to reframe problems from probability theory and statistics, making them accessible to students across diverse academic fields including biology, economics, law, and ... -
(2021-09-17)Epithelial-to-mesenchymal transition (EMT) is fundamental to both normal tissue development and cancer progression. We hypothesized that EMT plasticity defines a range of metabolic phenotypes and that individual breast epithelial metabolic phenotypes ...
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(2021-01-13)Magmatic volatile phases within crustal silicic magma domains influence key volcanic processes such as the build up to eruptions and formation of magmatic-hydrothermal ore deposits. However, the extent and nature of fluid-melt interaction in such ...
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(2021-12-16)Background: Anterior cruciate ligament (ACL) injuries have been studied using a variety of methods and tools. However, each is hindered by specific limitations with respect to its application. Aim: To assess the combined effects of external moments and ...
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(2023-06-10)Genotypes causing pregnancy loss and perinatal mortality are depleted among living individuals and are therefore difficult to find. To explore genetic causes of recessive lethality, we searched for sequence variants with deficit of homozygosity among ...
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(Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag, 2022-01-22)
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(2022-09-28)By the end of July 2021, the majority of the Icelandic population had received vaccination against COVID-19. In mid-July a wave of SARS-CoV-2 infections, dominated by the Delta variant, spread through the population, followed by an Omicron wave in ...
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(Institute of Electrical and Electronics Engineers Inc., 2022)
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(2022-01-10)Thousands of non-coding variants have been associated with increased risk of human diseases, yet the causal variants and their mechanisms-of-action remain obscure. In an integrative study combining massively parallel reporter assays (MPRA), expression ...
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(Association for Computational Linguistics, 2023-05-01)The methods used to create many of the well-known Question-Answering (QA) datasets are hard to replicate for low-resource languages. A commonality amongst these methods is hiring annotators to source answers from the internet by querying a single answer ...
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(2022-06-01)The characteristic lobulated nuclear morphology of granulocytes is partially determined by composition of nuclear envelope proteins. Abnormal nuclear morphology is primarily observed as an increased number of hypolobulated immature neutrophils, called ...
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(2021-02-13)Aims: The aim of this study was to use human genetics to investigate the pathogenesis of sick sinus syndrome (SSS) and the role of risk factors in its development. Methods and results: We performed a genome-wide association study of 6469 SSS cases and ...
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(2023-12)Clonal hematopoiesis (CH) arises when a substantial proportion of mature blood cells is derived from a single hematopoietic stem cell lineage. Using whole-genome sequencing of 45,510 Icelandic and 130,709 UK Biobank participants combined with a mutational ...
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(2021-02-03)Iron is essential for many biological functions and iron deficiency and overload have major health implications. We performed a meta-analysis of three genome-wide association studies from Iceland, the UK and Denmark of blood levels of ferritin (N = ...
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(2021-04)Multiple myeloma (MM) is caused by the uncontrolled, clonal expansion of plasma cells. While there is epidemiological evidence for inherited susceptibility, the molecular basis remains incompletely understood. We report a genome-wide association study ...
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(2022-09-06)Memory T-cell responses following SARS-CoV-2 infection have been extensively investigated but many studies have been small with a limited range of disease severity. Here we analyze SARS-CoV-2 reactive T-cell responses in 768 convalescent SARS-CoV-2-infected ...
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(2023-10-04)High-throughput proteomics platforms measuring thousands of proteins in plasma combined with genomic and phenotypic information have the power to bridge the gap between the genome and diseases. Here we performed association studies of Olink Explore ...
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(2022-04-25)Objectives To find causal genes for rheumatoid arthritis (RA) and its seropositive (RF and/or ACPA positive) and seronegative subsets. Methods We performed a genome-wide association study (GWAS) of 31 313 RA cases (68% seropositive) and ∼1 million ...
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(2022-10-24)Nonalcoholic fatty liver (NAFL) and its sequelae are growing health problems. We performed a genome-wide association study of NAFL, cirrhosis and hepatocellular carcinoma, and integrated the findings with expression and proteomic data. For NAFL, we ...
Atriði 1-20 af 26