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Browsing by Author "Jagtap, Anil P."

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bcTol: a highly water-soluble biradical for efficient dynamic nuclear polarization of biomolecules

Jagtap, Anil P.; Geiger, Michel-Andreas; Stöppler, Daniel; Orwick-Rydmark, Marcella; Oschkinat, Hartmut; Sigurdsson, Snorri (Royal Society of Chemistry (RSC), 2016)

Dynamic nuclear polarization (DNP) is an efficient method to overcome the inherent low sensitivity of magic-angle spinning (MAS) solid-state NMR. We report a new polarizing agent (bcTol), designed for biological applications, that yielded an enhancement ...
Site-directed spin labeling of 2′-amino groups in RNA with isoindoline nitroxides that are resistant to reduction

Saha, Subham; Jagtap, Anil P.; Sigurdsson, Snorri (Royal Society of Chemistry (RSC), 2015)

Two aromatic isothiocyanates, derived from isoindoline nitroxides, were synthesized and selectively reacted with 2′-amino groups in RNA. The spin labels displayed limited mobility in RNA, making them promising candidates for distance measurements by ...

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