Clinical decision support system for the management of osteoporosis compared to NOGG guidelines and an osteology specialist: a validation pilot study

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dc.contributorHáskóli Íslandsen_US
dc.contributorUniversity of Icelanden_US
dc.contributorHáskólinn í Reykjavíken_US
dc.contributorReykjavik Universityen_US
dc.contributor.authorGuðmundsson, Haukur Týr
dc.contributor.authorHansen, Karen E.
dc.contributor.authorHalldórsson, Bjarni
dc.contributor.authorLudviksson, Bjorn
dc.contributor.authorGudbjornsson, Bjorn
dc.contributor.departmentLæknadeild (HÍ)en_US
dc.contributor.departmentFaculty of Medicine (UI)en_US
dc.contributor.schoolHeilbrigðisvísindasvið (HÍ)en_US
dc.contributor.schoolSchool of Health Sciences (UI)en_US
dc.contributor.schoolSchool of Science and Engineering (RU)en_US
dc.contributor.schoolTækni- og verkfræðideild (HR)en_US
dc.date.accessioned2020-05-18T13:34:56Z
dc.date.available2020-05-18T13:34:56Z
dc.date.issued2019-02-01
dc.descriptionPublisher's version (útgefin grein)en_US
dc.description.abstractBackground: Although osteoporosis is an easily diagnosed and treatable condition, many individuals remain untreated. Clinical decision support systems might increase appropriate treatment of osteoporosis. We designed the Osteoporosis Advisor (OPAD), a computerized tool to support physicians managing osteoporosis at the point-of-care. The present study compares the treatment recommendations provided by OPAD, an expert physician and the National Osteoporosis Guideline Group (NOGG). Methods: We performed a retrospective analysis of 259 patients attending the outpatient osteoporosis clinic at the University Hospital in Iceland. We entered each patient's data into the OPAD and recorded the OPAD diagnostic comments, 10-year risk of major osteoporotic fracture and treatment options. We compared OPAD recommendations to those given by the osteoporosis specialist, and to those of the NOGG. Results: Risk estimates made by OPAD were highly correlated with those from FRAX (r = 0.99, 95% CI 0.99, 1.00 without femoral neck BMD; r = 0.98, 95% CI, 0.97, 0.99 with femoral neck BMD. Reassurance was recommended by the expert, NOGG and the OPAD in 68, 63 and 52% of cases, respectively. Likewise, intervention was recommended by the expert, NOGG, and the OPAD in 32, 37 and 48% of cases, respectively. The OPAD demonstrated moderate agreement with the physician (kappa 0.51, 95% CI 0.41, 0.61) and even higher agreement with NOGG (kappa 0.69, 95% CI 0.60, 0.77). Conclusion: Primary care physicians can use the OPAD to assess and treat patients' skeletal health. Recommendations given by OPAD are consistent with expert opinion and existing guidelines.en_US
dc.description.sponsorshipThis research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.en_US
dc.description.versionPeer Revieweden_US
dc.format.extent27en_US
dc.identifier.citationGudmundsson, H.T., Hansen, K.E., Halldorsson, B.V. et al. Clinical decision support system for the management of osteoporosis compared to NOGG guidelines and an osteology specialist: a validation pilot study. BMC Medical Informatics and Decision Making 19, 27 (2019). https://doi.org/10.1186/s12911-019-0749-4en_US
dc.identifier.doi10.1186/s12911-019-0749-4
dc.identifier.issn1472-6947
dc.identifier.journalBMC Medical Informatics and Decision Makingen_US
dc.identifier.urihttps://hdl.handle.net/20.500.11815/1813
dc.language.isoenen_US
dc.publisherSpringer Science and Business Media LLCen_US
dc.relation.ispartofseriesBMC Medical Informatics and Decision Making;19(1)
dc.relation.urlhttps://bmcmedinformdecismak.biomedcentral.com/articles/10.1186/s12911-019-0749-4en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectClinical decision support system (CDSS)en_US
dc.subjectClinical guidelinesen_US
dc.subjectFracture risken_US
dc.subjectOsteoporosisen_US
dc.subjectTreatment recommendationsen_US
dc.subjectBeinþynningen_US
dc.subjectUpplýsingakerfien_US
dc.subjectSjúkdómsgreiningen_US
dc.subjectÁhættuþættiren_US
dc.titleClinical decision support system for the management of osteoporosis compared to NOGG guidelines and an osteology specialist: a validation pilot studyen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dcterms.licenseOpen Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.en_US

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