Outcome After Surgery for Acute Type A Aortic Dissection With or Without Primary Tear Resection

dc.contributor.authorUimonen, Mikko
dc.contributor.authorOlsson, Christian
dc.contributor.authorJeppsson, Anders
dc.contributor.authorGeirsson, Arnar
dc.contributor.authorChemtob, Raphaelle
dc.contributor.authorKhalil, Ahmad
dc.contributor.authorHjortdal, Vibeke
dc.contributor.authorHansson, Emma C.
dc.contributor.authorNozohoor, Shahab
dc.contributor.authorZindovic, Igor
dc.contributor.authorGunn, Jarmo
dc.contributor.authorWickbom, Anders
dc.contributor.authorAhlsson, Anders
dc.contributor.authorGuðbjartsson, Tómas
dc.contributor.authorMennander, Ari
dc.contributor.departmentFaculty of Medicine
dc.date.accessioned2025-11-20T09:05:45Z
dc.date.available2025-11-20T09:05:45Z
dc.date.issued2022-08-01
dc.descriptionFunding Information: This study was funded by the Competitive State Research Financing of the Expert Responsibility area of Tampere University Hospital and the Finnish Cultural Foundation from Pirkanmaa Regional Fund (Dr Mennander), The Mats Kleberg Foundation , Stockholm, Sweden (Dr Olsson), and the University of Iceland Research Fund and the Lanspitali Research Fund (Dr. Gudbjartsson). Publisher Copyright: © 2022 The Society of Thoracic Surgeonsen
dc.description.abstractBackground: The outcome in patients after surgery for acute type A aortic dissection without replacement of the part of the aorta containing the primary tear is undefined. Methods: Data of 1122 patients who underwent surgery for acute type A aortic dissection in 8 Nordic centers from January 2005 to December 2014 were retrospectively analyzed. The patients with primary tear location unfound, unknown, not confirmed, or not recorded (n = 243, 21.7%) were excluded from the analysis. The patients were divided into 2 groups according to whether the aortic reconstruction encompassed the portion of the primary tear (tear resected [TR] group, n = 730) or not (tear not resected [TNR] group, n = 149). The restricted mean survival time ratios adjusted for patient characteristics and surgical details between the groups were calculated for all-cause mortality and aortic reoperation–free survival. The median follow-up time was 2.57 (interquartile range, 0.53-5.30) years. Results: For the majority of the patients in the TR group, the primary tear was located in the ascending aorta (83.6%). The reconstruction encompassed both the aortic root and the aortic arch in 7.4% in the TR group as compared with 0.7% in the TNR patients (P < .001). There were no significant differences in all-cause mortality (adjusted restricted mean survival time ratio, 1.01; 95% confidence interval, 0.92-1.12; P = .799) or reoperation-free survival (adjusted restricted mean survival time ratio, 0.98; 95% confidence interval, 0.95-1.02; P = .436) between the TR and TNR groups. Conclusions: Primary tear resection alone does not determine the midterm outcome after surgery for acute type A aortic dissection.en
dc.description.versionPeer revieweden
dc.format.extent10
dc.format.extent1002284
dc.format.extent492-501
dc.identifier.citationUimonen, M, Olsson, C, Jeppsson, A, Geirsson, A, Chemtob, R, Khalil, A, Hjortdal, V, Hansson, E C, Nozohoor, S, Zindovic, I, Gunn, J, Wickbom, A, Ahlsson, A, Guðbjartsson, T & Mennander, A 2022, 'Outcome After Surgery for Acute Type A Aortic Dissection With or Without Primary Tear Resection', Annals of Thoracic Surgery, vol. 114, no. 2, pp. 492-501. https://doi.org/10.1016/j.athoracsur.2021.09.067en
dc.identifier.doi10.1016/j.athoracsur.2021.09.067
dc.identifier.issn0003-4975
dc.identifier.other70335737
dc.identifier.other4abe1489-a2af-421c-91ec-a9f05854d195
dc.identifier.other85123620613
dc.identifier.other34774491
dc.identifier.otherunpaywall: 10.1016/j.athoracsur.2021.09.067
dc.identifier.urihttps://hdl.handle.net/20.500.11815/7045
dc.language.isoen
dc.relation.ispartofseriesAnnals of Thoracic Surgery; 114(2)en
dc.relation.urlhttps://www.scopus.com/pages/publications/85123620613en
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.subjectAcute Diseaseen
dc.subjectAortic Dissection/surgeryen
dc.subjectAorta/surgeryen
dc.subjectAortic Aneurysm, Thoracic/surgeryen
dc.subjectBlood Vessel Prosthesis Implantationen
dc.subjectFollow-Up Studiesen
dc.subjectHumansen
dc.subjectLacerations/surgeryen
dc.subjectRetrospective Studiesen
dc.subjectTreatment Outcomeen
dc.subjectCardiology and Cardiovascular Medicineen
dc.subjectPulmonary and Respiratory Medicineen
dc.subjectSurgeryen
dc.titleOutcome After Surgery for Acute Type A Aortic Dissection With or Without Primary Tear Resectionen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/articleen

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