Non-infectious sternal dehiscence after coronary artery bypass surgery

dc.contributor.authorSilverborn, Per Martin
dc.contributor.authorHeitmann, Leon Arnar
dc.contributor.authorSveinsdóttir, Nanna
dc.contributor.authorRögnvaldsson, Sigurjon
dc.contributor.authorKristjánsson, Tómas Þór
dc.contributor.authorGuðbjartsson, Tómas
dc.contributor.departmentFaculty of Medicine
dc.date.accessioned2025-11-20T08:50:42Z
dc.date.available2025-11-20T08:50:42Z
dc.date.issued2022-10-03
dc.descriptionFunding Information: This study was funded by the University of Iceland Research Fund, Landspitali University Hospital Research Fund, and the Memorial Fund of Helga Jonsdottir & Sigurlidi Kristjansson. Publisher Copyright: © 2022, The Author(s). © 2022. The Author(s).en
dc.description.abstractIntroduction: Non-infectious sternal dehiscence (NISD) is a known complication following coronary artery bypass grafting (CABG), with previous studies estimating an incidence of 0.4–1% of surgeries. We aimed to study the incidence of NISD together with short- and long-term outcomes in a whole-nation cohort of patients. Materials and methods: A retrospective study on consecutive CABG patients diagnosed with NISD at Landspitali from 2001 to 2020. Patients diagnosed with infectious mediastinitis (n = 20) were excluded. NISD patients were compared to patients with an intact sternum regarding patient demographics, cardiovascular risk factors, intra- and postoperative data, and estimated overall survival. The median follow-up was 9.5 years. Results: Twenty out of 2280 eligible patients (0.88%) developed NISD, and the incidence did not change over the study period (p = 0.98). The median time of diagnosis was 12 days postoperatively (range, 4–240). All patients were re-operated using a Robicsek-rewiring technique, with two cases requiring a titanium plate for fixation. Patients with NISD were older, had a higher BMI and EuroSCORE II, lower LVEF, and more often had a history of COPD, MI, and diabetes compared to those without NISD. Length of stay was extended by 15 days for NISD patients, but short and long-term survival was not statistically different between the groups. Conclusions: The incidence of NISD was low and in line with previous studies. Although the length of hospital stay was extended, both short- and long-term survival of NISD patients was not significantly different from patients with an intact sternum.en
dc.description.versionPeer revieweden
dc.format.extent1007827
dc.format.extent249
dc.identifier.citationSilverborn, P M, Heitmann, L A, Sveinsdóttir, N, Rögnvaldsson, S, Kristjánsson, T Þ & Guðbjartsson, T 2022, 'Non-infectious sternal dehiscence after coronary artery bypass surgery', Journal of Cardiothoracic Surgery, vol. 17, no. 1, 249, pp. 249. https://doi.org/10.1186/s13019-022-02015-1en
dc.identifier.doi10.1186/s13019-022-02015-1
dc.identifier.issn1749-8090
dc.identifier.other62214480
dc.identifier.otherbba49c9f-4528-4f35-9587-e23c56d30925
dc.identifier.other85139175034
dc.identifier.other36192764
dc.identifier.otherunpaywall: 10.1186/s13019-022-02015-1
dc.identifier.urihttps://hdl.handle.net/20.500.11815/6800
dc.language.isoen
dc.relation.ispartofseriesJournal of Cardiothoracic Surgery; 17(1)en
dc.relation.urlhttps://www.scopus.com/pages/publications/85139175034en
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.subjectCoronary Artery Bypass/adverse effectsen
dc.subjectHumansen
dc.subjectMediastinitis/epidemiologyen
dc.subjectRetrospective Studiesen
dc.subjectRisk Factorsen
dc.subjectSternum/surgeryen
dc.subjectTitaniumen
dc.subjectCardiology and Cardiovascular Medicineen
dc.subjectPulmonary and Respiratory Medicineen
dc.subjectSurgeryen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.titleNon-infectious sternal dehiscence after coronary artery bypass surgeryen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/articleen

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