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Fletta eftir efnisorði "Efnaskipti"
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2023-11-16)ATG7, an essential protein for cellular homeostasis, plays a pivotal role in regulating autophagy. The autophagy process ensures the degradation and recycling of cellular components for proper cell function. ATG7 facilitates the lipidation of ATG8 ... -
(University of Iceland, School of Health Sciences, Faculty of Medicine, 2022-05-24)Breast cancer is the leading cause of cancer deaths among women in Iceland and worldwide. Epithelial-mesenchymal transition (EMT) is a cellular developmental process where epithelial cells assume mesenchymal-like phenotypes through degradation of the ...
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Examining the link between maternal nutrition, gestational weight gain, and later offspring health (University of Iceland, School of Health Sciences, Faculty of Food Science and Nutrition, 2018-01)Aim: The aim of this Ph.D. thesis is to enhance understanding of the relation between maternal diet, gestational weight gain (GWG), and offspring’s cardio-metabolic factors. Moreover, the objective is to identify dietary predictors for excessive GWG. ...
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Metabolic systems analysis of breast epithelial cells following epithelial-to-mesenchymal transition (University of Iceland, School of Health Sciences, Faculty of Medicine, 2022-02-25)Breast cancer is a heterogenous disease in which the mechanism for signalling, gene expression, metabolism and growth in breast tissue is deranged. Breast cancer is responsible for the death of over 600,000 people worldwide on a yearly basis. By ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2016-12)Studying human metabolism is crucial for the understanding of diseases and improvement of therapy as metabolic alterations are central to a number of human diseases. A variety of experimental disciplines, such as biochemistry, biophysics and systems ...
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