Opin vísindi

Fletta eftir efnisorði "Sameindalíffræði"

Fletta eftir efnisorði "Sameindalíffræði"

Röðun: Raða: Niðurstöður:

  • Icon
    The Malignant Role of Exosomes as Nanocarriers of Rare RNA Species 
    Zimta, Alina-Andreea; Sigurjonsson, Olafur Eysteinn; Gulei, Diana; Tomuleasa, Ciprian (MDPI AG, 2020-08-15)
    Nowadays, advancements in the oncology sector regarding diagnosis methods allow us to specifically detect an increased number of cancer patients, some of them in incipient stages. However, one of the main issues consists of the invasive character of ...
  • Icon
    Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017 
    Nigatu, Yeshambel Tesfa; Sigfúsdóttir, Inga Dóra (Springer Science and Business Media LLC, 2020-04-20)
    A double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 ...
  • Icon
    POGZ Is Required for Silencing Mouse Embryonic β-like Hemoglobin and Human Fetal Hemoglobin Expression 
    Gudmundsdottir, Bjorg; Gudmundsson, Kristbjorn Orri; Klarmann, Kimberly D.; Singh, Satyendra K.; Sun, Lei; Singh, Shweta; Du, Yang; Coppola, Vincenzo; Stockwin, Luke; Nguyen, Nhu; Tessarollo, Lino; Thorsteinsson, Leifur; Sigurjonsson, Olafur; Gudmundsson, Sveinn Vidar; Rafnar, Thorunn; Tisdale, John F.; Keller, Jonathan R. (Elsevier BV, 2018-06-12)
    Fetal globin genes are transcriptionally silenced during embryogenesis through hemoglobin switching. Strategies to derepress fetal globin expression in the adult could alleviate symptoms in sickle cell disease and β-thalassemia. We identified a zinc-finger ...
  • Icon
    popSTR2 enables clinical and population-scale genotyping of microsatellites 
    Kristmundsdottir, Snædis; Eggertsson, Hannes P; Arnadottir, Gudny A; Halldórsson, Bjarni (Oxford University Press (OUP), 2019-12-05)
    Summary: popSTR2 is an update and augmentation of our previous work ‘popSTR: a population-based microsatellite genotyper’. To make genotyping sensitive to inter-sample differences, we supply a kernel to estimate sample-specific slippage rates. For ...
  • Icon
    Sequence variants associating with urinary biomarkers 
    Benonisdottir, Stefania; Kristjansson, Ragnar P; Oddsson, Asmundur; Steinthorsdottir, Valgerdur; Mikaelsdottir, Evgenia; Kehr, Birte; Jensson, Brynjar O; Arnadottir, Gudny A; Sulem, Gerald; Sveinbjornsson, Gardar; Kristmundsdóttir, Snædís; Ívarsdóttir, Erna V.; Tragante, Vinicius; Gunnarsson, Bjarni; Runolfsdottir, Hrafnhildur Linnet; Arthur, Joseph G; Deaton, Aimee M; Eyjolfsson, Gudmundur I; Davidsson, Olafur B; Asselbergs, Folkert W; Hreidarsson, Astradur B; Rafnar, Thorunn; Thorleifsson, Gudmar; Edvardsson, Vidar; Sigurdsson, Gunnar; Helgadottir, Anna; Halldórsson, Bjarni; Masson, Gisli; Holm, Hilma; Önundarson, Páll Torfi; Indridason, Olafur S; Benediktsson, Rafn; Palsson, Runolfur; Gudbjartsson, Daniel F; Olafsson, Isleifur; Thorsteinsdottir, Unnur; sulem, patrick; Stefansson, Kari (Oxford University Press (OUP), 2018-11-24)
    Urine dipstick tests are widely used in routine medical care to diagnose kidney and urinary tract and metabolic diseases. Several environmental factors are known to affect the test results, whereas the effects of genetic diversity are largely unknown. ...
  • Icon
    Systems biology as an emerging paradigm in transfusion medicine 
    Yurkovich, James; Bordbar, Aarash; Sigurjonsson, Olafur; Palsson, Bernhard O. (Springer Nature, 2018-03-07)
    Blood transfusions are an important part of modern medicine, delivering approximately 85 million blood units to patients annually. Recently, the field of transfusion medicine has started to benefit from the “omic” data revolution and corresponding ...