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Fletta eftir efnisorði "Macroautophagy"

Fletta eftir efnisorði "Macroautophagy"

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    MITF has a central role in regulating starvation-induced autophagy in melanoma 
    Möller, Katrin; Sigurbjornsdottir, Sara; Arnþórsson, Ásgeir O.; Pogenberg, Vivian; Dilshat, Ramile; Fock, Valerie; Brynjólfsdóttir, Sólveig Hlín; Bindesboll, Christian; Bessadóttir, Margrét; Ögmundsdóttir, Helga M.; Simonsen, Anne; Larue, Lionel; Wilmanns, Matthias; Thorsson, Vésteinn; Steingrimsson, Eirikur; Ogmundsdottir, Margret H (Springer Science and Business Media LLC, 2019-01-31)
    The MITF transcription factor is a master regulator of melanocyte development and a critical factor in melanomagenesis. The related transcription factors TFEB and TFE3 regulate lysosomal activity and autophagy processes known to be important in ...
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    A short isoform of ATG7 fails to lipidate LC3/GABARAP 
    Ogmundsdottir, Margret H; Fock, Valerie; Sooman, L.; Pogenberg, V.; Dilshat, R.; Bindesbøll, C.; Ögmundsdóttir, Helga M.; Simonsen, A.; Wilmanns, M.; Steingrimsson, Eirikur (Springer Science and Business Media LLC, 2018-09-26)
    Autophagy is a degradation pathway important for cellular homeostasis. The E1-like enzyme ATG7 is a key component of the autophagy machinery, with the main function of mediating the lipidation of LC3/GABARAP during autophagosome formation. By analysing ...