Browsing Háskóli Íslands by Author "Óskarsson, Kristinn Ragnar"

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Kinetic stability and temperature adaptation. Observations from a cold adapted subtilisin-like serine protease.

Óskarsson, Kristinn Ragnar (University of Iceland, School of Engineering and Natural Sciences, Faculty of Physical Sciences, 2020-10)

Life on earth is found everywhere where water is found, meaning that life has adapted to extremely varied environments. Thus, protein structures must adapt to a myriad of environmental stressors while maintaining their functional forms. In the case ...
Thermostabilization of VPR, a kinetically stable cold adapted subtilase, via multiple proline substitutions into surface loops

Óskarsson, Kristinn Ragnar; Sævarsson, Arnór Freyr; Kristjánsson, Magnús M. (Springer Science and Business Media LLC, 2020-01-23)

Protein stability is a widely studied topic, there are still aspects however that need addressing. In this paper we examined the effects of multiple proline substitutions into loop regions of the kinetically stable proteinase K-like serine protease ...

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