Browsing Háskóli Íslands by Author "Chebib, Mary"

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Concatenated γ-aminobutyric acid type A receptors revisited: Finding order in chaos

Liao, Vivian Wan Yu; Chua, Han Chow; Kowal, Natalia Magdalena; Chebib, Mary; Balle, Thomas; Ahring, Philip Kiær (Rockefeller University Press, 2019-04-15)

γ-aminobutyric acid type A receptors (GABAARs), the major inhibitory neurotransmitter receptors in the mammalian central nervous system, are arguably the most challenging member of the pentameric Cys-loop receptors to study due to their heteromeric ...
Novel Approach for the Search for Chemical Scaffolds with Activity at Both Acetylcholinesterase and the α7 Nicotinic Acetylcholine Receptor: A Perspective on Scaffolds with Dual Activity for the Treatment of Neurodegenerative Disorders

Kowal, Natalia Magdalena; Indurthi, Dinesh; Ahring, Philip; Chebib, Mary; Olafsdottir, Elin Soffia; Balle, Thomas (MDPI AG, 2019-01-27)

Neurodegenerative disorders, including Alzheimer’s disease, belong to the group of the most difficult and challenging conditions with very limited treatment options. Attempts to find new drugs in most cases fail at the clinical stage. New tactics to ...

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