Browsing Háskóli Íslands by Author "Ostrowski, Sisse Rye"

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Co-administration of iloprost and eptifibatide in septic shock (CO-ILEPSS)—a randomised, controlled, double-blind investigator-initiated trial investigating safety and efficacy

Berthelsen, Rasmus Ehrenfried; Ostrowski, Sisse Rye; Bestle, Morten Heiberg; Johansson, Pär Ingemar (Springer Science and Business Media LLC, 2019-09-05)

Background: Part of the pathophysiology in septic shock is a progressive activation of the endothelium and platelets leading to widespread microvascular injury with capillary leakage, microthrombi and consumption coagulopathy. Modulating the inflammatory ...
Shock induced endotheliopathy (SHINE) in acute critical illness - a unifying pathophysiologic mechanism

Johansson, Pär Ingemar; Stensballe, Jakob; Ostrowski, SisseRye (Springer Nature, 2017-02-09)

One quarter of patients suffering from acute critical illness such as severe trauma, sepsis, myocardial infarction (MI) or post cardiac arrest syndrome (PCAS) develop severe hemostatic aberrations and coagulopathy, which are associated with excess ...

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