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Factor B Mutation in Monozygotic Twins Discordant for Atypical Hemolytic Uremic Syndrome

Factor B Mutation in Monozygotic Twins Discordant for Atypical Hemolytic Uremic Syndrome


Title: Factor B Mutation in Monozygotic Twins Discordant for Atypical Hemolytic Uremic Syndrome
Author: Aradottir, Sigridur Sunna
Kristoffersson, Ann-Charlotte
Jensson, Brynjar O
Sulem, Patrick   orcid.org/0000-0001-7123-6123
Gong, Henning
Pálsson, Runólfur
Karpman, Diana
Date: 2023-05
Language: English
Scope: 5
Department: Other departments
Faculty of Medicine
Series: Kidney International Reports; 8(5)
ISSN: 2468-0249
DOI: 10.1016/j.ekir.2023.02.1069
Subject: Nýrnalæknisfræði; atypical hemolytic uremic syndrome; complement; Factor B; genetics; monozygotic twins; Nephrology
URI: https://hdl.handle.net/20.500.11815/4215

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Citation:

Aradottir , S S , Kristoffersson , A-C , Jensson , B O , Sulem , P , Gong , H , Pálsson , R & Karpman , D 2023 , ' Factor B Mutation in Monozygotic Twins Discordant for Atypical Hemolytic Uremic Syndrome ' , Kidney International Reports , vol. 8 , no. 5 , pp. 1097-1101 . https://doi.org/10.1016/j.ekir.2023.02.1069

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Funding Information: The authors acknowledge scientific discussions with Professor Nancy Segal, California State University Fullerton. We are grateful for bioinformatic expertise provided by Dr. Petter Storm, Lund University. We thank Dr. Ida Arvidsson, Dr. Annie Willysson, and Dr. Ashmita Tontanahal of the Department of Pediatrics, Lund University for their help with microscopy and quantification. This paper was presented in poster form at the 18th European Meeting on Complement in Human Disease 26-29/8, 2022 in Bern Switzerland. The authors are grateful to the patients and their family members for participating in the study. The Swedish Research Council (2020-02200, 2017-01920), The Knut and Alice Wallenberg Foundation (Wallenberg Clinical Scholar 2015.0320), Skåne Centre of Excellence in Health, The Inga-Britt and Arne Lundberg's Research Foundation, Kidneeds Fund, Olle Engkvist Byggmästare Foundation and The Swedish Freemason's Foundation for Children's Welfare (all to DK). Funding Information: The Swedish Research Council ( 2020-02200, 2017-01920 ), The Knut and Alice Wallenberg Foundation (Wallenberg Clinical Scholar 2015.0320), Skåne Centre of Excellence in Health, The Inga-Britt and Arne Lundberg’s Research Foundation, Kidneeds Fund, Olle Engkvist Byggmästare Foundation and The Swedish Freemason’s Foundation for Children’s Welfare (all to DK).

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