Titill: | Respiratory outcomes after delivery room stabilisation with a new respiratory support system using nasal prongs |
Höfundur: |
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Útgáfa: | 2023-04 |
Tungumál: | Enska |
Umfang: | 7 |
Háskóli/Stofnun: | Landspitali - The National University Hospital of Iceland |
Birtist í: | Acta Paediatrica, International Journal of Paediatrics; 112(4) |
ISSN: | 0803-5253 |
DOI: | 10.1111/apa.16665 |
Efnisorð: | Barnalæknisfræði; bronchopulmonary dysplasia; delivery room; nasal prongs; pre-term; stabilisation; Follow-Up Studies; Humans; Infant; Bronchopulmonary Dysplasia; Respiration, Artificial; Pregnancy; Delivery Rooms; Infant, Premature; Adolescent; Respiratory Distress Syndrome, Newborn/diagnosis; Female; Infant, Newborn; Pediatrics, Perinatology and Child Health |
URI: | https://hdl.handle.net/20.500.11815/4050 |
Tilvitnun:Baldursdottir , S , Dónaldsson , S F , Palleri , E , Drevhammar , T & Jonsson , B 2023 , ' Respiratory outcomes after delivery room stabilisation with a new respiratory support system using nasal prongs ' , Acta Paediatrica, International Journal of Paediatrics , vol. 112 , no. 4 , pp. 719-725 . https://doi.org/10.1111/apa.16665
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Útdráttur:AIM: To study if stabilisation using a new respiratory support system with nasal prongs compared to T-piece with a face mask is associated with less need for mechanical ventilation and bronchopulmonary dysplasia. METHODS: A single-centre follow-up study of neonates born <28 weeks gestation at Karolinska University Hospital, Stockholm included in the multicentre Comparison of Respiratory Support after Delivery (CORSAD) trial and randomised to initial respiratory support with the new system versus T-piece. Data on respiratory support, neonatal morbidities and mortality were collected up to 36 weeks post-menstrual age. RESULTS: Ninety-four infants, 51 female, with a median (range) gestational age of 25 + 2 (23 + 0, 27 + 6) weeks and days, were included. Significantly fewer infants in the new system group received mechanical ventilation during the first 72 h, 24 (52.2%) compared with 35 (72.9%) (p = 0.034) and during the first 7 days, 29 (63.0%) compared with 39 (81.3%) (p = 0.045) in the T-piece group. At 36 weeks post-menstrual age, 13 (28.3%) in the new system and 13 (27.1%) in the T-piece group were diagnosed with bronchopulmonary dysplasia. CONCLUSION: Stabilisation with the new system was associated with less need for mechanical ventilation during the first week of life. No significant difference was seen in the outcome of bronchopulmonary dysplasia.
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Athugasemdir:Funding Information: The study was funded by H.K.H. Kronprinsessan Lovisas Förening för Barnasjukvård, Sällskapet Barnavård Research Fund, Region Stockholm and the Swedish Heart-Lung Fund. Funding Information: The study was funded by H.K.H. Kronprinsessan Lovisas Förening för Barnasjukvård, Sällskapet Barnavård Research Fund, Region Stockholm and the Swedish Heart‐Lung Fund. Publisher Copyright: © 2023 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica.
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