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Increasing numbers and improved overall survival of patients on kidney replacement therapy over the last decade in Europe : an ERA Registry study

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dc.contributor.author Huijben, Jilske A
dc.contributor.author Kramer, Anneke
dc.contributor.author Kerschbaum, Julia
dc.contributor.author de Meester, Johan
dc.contributor.author Collart, Frederic
dc.contributor.author Arévalo, Olga Lucía Rodríguez
dc.contributor.author Helve, Jaakko
dc.contributor.author Lassalle, Mathilde
dc.contributor.author Pálsson, Runólfur
dc.contributor.author Ten Dam, Marc
dc.contributor.author Casula, Anna
dc.contributor.author Methven, Shona
dc.contributor.author Ortiz, Alberto
dc.contributor.author Ferraro, Pietro Manuel
dc.contributor.author Segelmark, Mårten
dc.contributor.author Mingo, Pablo Ucio
dc.contributor.author Arici, Mustafa
dc.contributor.author Reisæter, Anna Varberg
dc.contributor.author Stendahl, Maria
dc.contributor.author Stel, Vianda S
dc.contributor.author Jager, Kitty J
dc.date.accessioned 2023-01-14T01:06:55Z
dc.date.available 2023-01-14T01:06:55Z
dc.date.issued 2023-04
dc.identifier.citation Huijben , J A , Kramer , A , Kerschbaum , J , de Meester , J , Collart , F , Arévalo , O L R , Helve , J , Lassalle , M , Pálsson , R , Ten Dam , M , Casula , A , Methven , S , Ortiz , A , Ferraro , P M , Segelmark , M , Mingo , P U , Arici , M , Reisæter , A V , Stendahl , M , Stel , V S & Jager , K J 2023 , ' Increasing numbers and improved overall survival of patients on kidney replacement therapy over the last decade in Europe : an ERA Registry study ' , Nephrology, dialysis, transplantation , vol. 38 , no. 4 , pp. 1027-1040 . https://doi.org/10.1093/ndt/gfac165
dc.identifier.issn 0931-0509
dc.identifier.other PURE: 72662191
dc.identifier.other PURE UUID: fa0fcb69-929f-4002-ab6d-b823fff5ff9c
dc.identifier.other Scopus: 85149453045
dc.identifier.uri https://hdl.handle.net/20.500.11815/3852
dc.description Funding Information: K.J.J. reports grants from the European Renal Association (ERA). All other authors declare no competing interests. The results presented in this paper have not been published previously in whole or part. Publisher Copyright: © 2022 The Author(s).
dc.description.abstract BACKGROUND: The aim of this study was to describe the trends in the incidence, prevalence and survival of patients on kidney replacement therapy (KRT) for end-stage kidney disease (ESKD) across Europe from 2008 to 2017. METHODS: Data from renal registries in 9 countries and 16 regions that provided individual patient data to the ERA Registry from 2008 to 2017 were included. These registries cover 34% of the general population in Europe. Crude and standardized incidence and prevalence per million population (pmp) were determined. Trends over time were studied using Joinpoint regression. Survival probabilities were estimated using Kaplan-Meier analysis and hazard ratios (HRs) using Cox regression analysis. RESULTS: The standardized incidence of KRT was stable [annual percentage change (APC): -1.48 (-3.15; 0.21)] from 2008 (146.0 pmp) to 2011 (141.6 pmp), followed by a slight increase [APC: 1.01 (0.43; 1.60)] to 148.0 pmp in 2017, although trends in incidence varied across countries. This increase was primarily due to a rise in the incidence of KRT in men older than 65 years. Moreover, as a cause of kidney failure, diabetes mellitus is increasing. The standardized prevalence increased from 2008 (990.0 pmp) to 2017 (1166.8 pmp) [APC: 1.82 (1.75; 1.89)]. Patient survival on KRT improved in the time period 2011-13 compared with 2008-[adjusted HR: 0.94 (0.93; 0.95)]. CONCLUSION: This study showed an overall increase in the incidence and prevalence of KRT for ESKD as well as an increase in the KRT patient survival over the last decade in Europe.
dc.format.extent 14
dc.format.extent 1027-1040
dc.language.iso en
dc.relation.ispartofseries Nephrology, dialysis, transplantation; 38(4)
dc.rights info:eu-repo/semantics/openAccess
dc.subject Nýrnalæknisfræði
dc.subject dialysis
dc.subject incidence
dc.subject kidney transplantation
dc.subject prevalence
dc.subject survival
dc.subject Humans
dc.subject Proportional Hazards Models
dc.subject Renal Replacement Therapy
dc.subject Male
dc.subject Kidney Failure, Chronic/epidemiology
dc.subject Incidence
dc.subject Europe/epidemiology
dc.subject Registries
dc.subject Nephrology
dc.subject Transplantation
dc.title Increasing numbers and improved overall survival of patients on kidney replacement therapy over the last decade in Europe : an ERA Registry study
dc.type /dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article
dc.description.version Peer reviewed
dc.identifier.pmid 35974693
dc.identifier.doi https://doi.org/10.1093/ndt/gfac165
dc.relation.url http://www.scopus.com/inward/record.url?scp=85149453045&partnerID=8YFLogxK
dc.contributor.department Other departments
dc.contributor.department Faculty of Medicine


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