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Outcome After Surgery for Acute Type A Aortic Dissection With or Without Primary Tear Resection

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dc.contributor.author Uimonen, Mikko
dc.contributor.author Olsson, Christian
dc.contributor.author Jeppsson, Anders
dc.contributor.author Geirsson, Arnar
dc.contributor.author Chemtob, Raphaelle
dc.contributor.author Khalil, Ahmad
dc.contributor.author Hjortdal, Vibeke
dc.contributor.author Hansson, Emma C.
dc.contributor.author Nozohoor, Shahab
dc.contributor.author Zindovic, Igor
dc.contributor.author Gunn, Jarmo
dc.contributor.author Wickbom, Anders
dc.contributor.author Ahlsson, Anders
dc.contributor.author Guðbjartsson, Tómas
dc.contributor.author Mennander, Ari
dc.date.accessioned 2023-01-10T01:05:14Z
dc.date.available 2023-01-10T01:05:14Z
dc.date.issued 2022-08-01
dc.identifier.citation Uimonen , M , Olsson , C , Jeppsson , A , Geirsson , A , Chemtob , R , Khalil , A , Hjortdal , V , Hansson , E C , Nozohoor , S , Zindovic , I , Gunn , J , Wickbom , A , Ahlsson , A , Guðbjartsson , T & Mennander , A 2022 , ' Outcome After Surgery for Acute Type A Aortic Dissection With or Without Primary Tear Resection ' , Annals of Thoracic Surgery , vol. 114 , no. 2 , pp. 492-501 . https://doi.org/10.1016/j.athoracsur.2021.09.067
dc.identifier.issn 0003-4975
dc.identifier.other 70335737
dc.identifier.other 4abe1489-a2af-421c-91ec-a9f05854d195
dc.identifier.other 85123620613
dc.identifier.other 34774491
dc.identifier.other unpaywall: 10.1016/j.athoracsur.2021.09.067
dc.identifier.uri https://hdl.handle.net/20.500.11815/3834
dc.description Funding Information: This study was funded by the Competitive State Research Financing of the Expert Responsibility area of Tampere University Hospital and the Finnish Cultural Foundation from Pirkanmaa Regional Fund (Dr Mennander), The Mats Kleberg Foundation , Stockholm, Sweden (Dr Olsson), and the University of Iceland Research Fund and the Lanspitali Research Fund (Dr. Gudbjartsson). Publisher Copyright: © 2022 The Society of Thoracic Surgeons
dc.description.abstract Background: The outcome in patients after surgery for acute type A aortic dissection without replacement of the part of the aorta containing the primary tear is undefined. Methods: Data of 1122 patients who underwent surgery for acute type A aortic dissection in 8 Nordic centers from January 2005 to December 2014 were retrospectively analyzed. The patients with primary tear location unfound, unknown, not confirmed, or not recorded (n = 243, 21.7%) were excluded from the analysis. The patients were divided into 2 groups according to whether the aortic reconstruction encompassed the portion of the primary tear (tear resected [TR] group, n = 730) or not (tear not resected [TNR] group, n = 149). The restricted mean survival time ratios adjusted for patient characteristics and surgical details between the groups were calculated for all-cause mortality and aortic reoperation–free survival. The median follow-up time was 2.57 (interquartile range, 0.53-5.30) years. Results: For the majority of the patients in the TR group, the primary tear was located in the ascending aorta (83.6%). The reconstruction encompassed both the aortic root and the aortic arch in 7.4% in the TR group as compared with 0.7% in the TNR patients (P < .001). There were no significant differences in all-cause mortality (adjusted restricted mean survival time ratio, 1.01; 95% confidence interval, 0.92-1.12; P = .799) or reoperation-free survival (adjusted restricted mean survival time ratio, 0.98; 95% confidence interval, 0.95-1.02; P = .436) between the TR and TNR groups. Conclusions: Primary tear resection alone does not determine the midterm outcome after surgery for acute type A aortic dissection.
dc.format.extent 10
dc.format.extent 1002284
dc.format.extent 492-501
dc.language.iso en
dc.relation.ispartofseries Annals of Thoracic Surgery; 114(2)
dc.rights info:eu-repo/semantics/openAccess
dc.subject Hjarta- og lungnaskurðlæknisfræði
dc.subject Acute Disease
dc.subject Aortic Dissection/surgery
dc.subject Aorta/surgery
dc.subject Aortic Aneurysm, Thoracic/surgery
dc.subject Blood Vessel Prosthesis Implantation
dc.subject Follow-Up Studies
dc.subject Humans
dc.subject Lacerations/surgery
dc.subject Retrospective Studies
dc.subject Treatment Outcome
dc.subject Cardiology and Cardiovascular Medicine
dc.subject Pulmonary and Respiratory Medicine
dc.subject Surgery
dc.title Outcome After Surgery for Acute Type A Aortic Dissection With or Without Primary Tear Resection
dc.type /dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article
dc.description.version Peer reviewed
dc.identifier.doi 10.1016/j.athoracsur.2021.09.067
dc.relation.url http://www.scopus.com/inward/record.url?scp=85123620613&partnerID=8YFLogxK
dc.contributor.department Faculty of Medicine
dc.contributor.department Other departments
dc.contributor.department Cardio-Vascular Center


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