Opin vísindi

Non-infectious sternal dehiscence after coronary artery bypass surgery

Non-infectious sternal dehiscence after coronary artery bypass surgery

Title: Non-infectious sternal dehiscence after coronary artery bypass surgery
Author: Silverborn, Per Martin
Heitmann, Leon Arnar
Sveinsdóttir, Nanna
Rögnvaldsson, Sigurjon
Kristjánsson, Tómas Þór
Guðbjartsson, Tómas
Date: 2022-10-03
Language: English
Scope: 249
University/Institute: Landspitali - The National University Hospital of Iceland
Department: Faculty of Medicine
Cardio-Vascular Center
Series: Journal of Cardiothoracic Surgery; 17(1)
ISSN: 1749-8090
DOI: https://doi.org/10.1186/s13019-022-02015-1
Subject: Hjarta- og lungnaskurðlæknisfræði; Coronary Artery Bypass/adverse effects; Humans; Mediastinitis/epidemiology; Retrospective Studies; Risk Factors; Sternum/surgery; Titanium; Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery
URI: https://hdl.handle.net/20.500.11815/3526

Show full item record


Silverborn , P M , Heitmann , L A , Sveinsdóttir , N , Rögnvaldsson , S , Kristjánsson , T Þ & Guðbjartsson , T 2022 , ' Non-infectious sternal dehiscence after coronary artery bypass surgery ' , Journal of Cardiothoracic Surgery , vol. 17 , no. 1 , 249 , pp. 249 . https://doi.org/10.1186/s13019-022-02015-1


Introduction: Non-infectious sternal dehiscence (NISD) is a known complication following coronary artery bypass grafting (CABG), with previous studies estimating an incidence of 0.4–1% of surgeries. We aimed to study the incidence of NISD together with short- and long-term outcomes in a whole-nation cohort of patients. Materials and methods: A retrospective study on consecutive CABG patients diagnosed with NISD at Landspitali from 2001 to 2020. Patients diagnosed with infectious mediastinitis (n = 20) were excluded. NISD patients were compared to patients with an intact sternum regarding patient demographics, cardiovascular risk factors, intra- and postoperative data, and estimated overall survival. The median follow-up was 9.5 years. Results: Twenty out of 2280 eligible patients (0.88%) developed NISD, and the incidence did not change over the study period (p = 0.98). The median time of diagnosis was 12 days postoperatively (range, 4–240). All patients were re-operated using a Robicsek-rewiring technique, with two cases requiring a titanium plate for fixation. Patients with NISD were older, had a higher BMI and EuroSCORE II, lower LVEF, and more often had a history of COPD, MI, and diabetes compared to those without NISD. Length of stay was extended by 15 days for NISD patients, but short and long-term survival was not statistically different between the groups. Conclusions: The incidence of NISD was low and in line with previous studies. Although the length of hospital stay was extended, both short- and long-term survival of NISD patients was not significantly different from patients with an intact sternum.


Funding Information: This study was funded by the University of Iceland Research Fund, Landspitali University Hospital Research Fund, and the Memorial Fund of Helga Jonsdottir & Sigurlidi Kristjansson. Publisher Copyright: © 2022, The Author(s). © 2022. The Author(s).

Files in this item

This item appears in the following Collection(s)