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Non-infectious sternal dehiscence after coronary artery bypass surgery

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dc.contributor Landspitali - The National University Hospital of Iceland
dc.contributor.author Silverborn, Per Martin
dc.contributor.author Heitmann, Leon Arnar
dc.contributor.author Sveinsdóttir, Nanna
dc.contributor.author Rögnvaldsson, Sigurjon
dc.contributor.author Kristjánsson, Tómas Þór
dc.contributor.author Guðbjartsson, Tómas
dc.date.accessioned 2022-10-21T01:04:38Z
dc.date.available 2022-10-21T01:04:38Z
dc.date.issued 2022-10-03
dc.identifier.citation Silverborn , P M , Heitmann , L A , Sveinsdóttir , N , Rögnvaldsson , S , Kristjánsson , T Þ & Guðbjartsson , T 2022 , ' Non-infectious sternal dehiscence after coronary artery bypass surgery ' , Journal of Cardiothoracic Surgery , vol. 17 , no. 1 , 249 , pp. 249 . https://doi.org/10.1186/s13019-022-02015-1
dc.identifier.issn 1749-8090
dc.identifier.other 62214480
dc.identifier.other bba49c9f-4528-4f35-9587-e23c56d30925
dc.identifier.other 85139175034
dc.identifier.other 36192764
dc.identifier.other unpaywall: 10.1186/s13019-022-02015-1
dc.identifier.uri https://hdl.handle.net/20.500.11815/3526
dc.description Funding Information: This study was funded by the University of Iceland Research Fund, Landspitali University Hospital Research Fund, and the Memorial Fund of Helga Jonsdottir & Sigurlidi Kristjansson. Publisher Copyright: © 2022, The Author(s). © 2022. The Author(s).
dc.description.abstract Introduction: Non-infectious sternal dehiscence (NISD) is a known complication following coronary artery bypass grafting (CABG), with previous studies estimating an incidence of 0.4–1% of surgeries. We aimed to study the incidence of NISD together with short- and long-term outcomes in a whole-nation cohort of patients. Materials and methods: A retrospective study on consecutive CABG patients diagnosed with NISD at Landspitali from 2001 to 2020. Patients diagnosed with infectious mediastinitis (n = 20) were excluded. NISD patients were compared to patients with an intact sternum regarding patient demographics, cardiovascular risk factors, intra- and postoperative data, and estimated overall survival. The median follow-up was 9.5 years. Results: Twenty out of 2280 eligible patients (0.88%) developed NISD, and the incidence did not change over the study period (p = 0.98). The median time of diagnosis was 12 days postoperatively (range, 4–240). All patients were re-operated using a Robicsek-rewiring technique, with two cases requiring a titanium plate for fixation. Patients with NISD were older, had a higher BMI and EuroSCORE II, lower LVEF, and more often had a history of COPD, MI, and diabetes compared to those without NISD. Length of stay was extended by 15 days for NISD patients, but short and long-term survival was not statistically different between the groups. Conclusions: The incidence of NISD was low and in line with previous studies. Although the length of hospital stay was extended, both short- and long-term survival of NISD patients was not significantly different from patients with an intact sternum.
dc.format.extent 1007827
dc.format.extent 249
dc.language.iso en
dc.relation.ispartofseries Journal of Cardiothoracic Surgery; 17(1)
dc.rights info:eu-repo/semantics/openAccess
dc.subject Hjarta- og lungnaskurðlæknisfræði
dc.subject Coronary Artery Bypass/adverse effects
dc.subject Humans
dc.subject Mediastinitis/epidemiology
dc.subject Retrospective Studies
dc.subject Risk Factors
dc.subject Sternum/surgery
dc.subject Titanium
dc.subject Cardiology and Cardiovascular Medicine
dc.subject Pulmonary and Respiratory Medicine
dc.subject Surgery
dc.title Non-infectious sternal dehiscence after coronary artery bypass surgery
dc.type /dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article
dc.description.version Peer reviewed
dc.identifier.doi 10.1186/s13019-022-02015-1
dc.relation.url http://www.scopus.com/inward/record.url?scp=85139175034&partnerID=8YFLogxK
dc.contributor.department Faculty of Medicine
dc.contributor.department Cardio-Vascular Center


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