dc.contributor |
Landspitali - The National University Hospital of Iceland |
dc.contributor.author |
Garðarsdóttir, Helga Rún |
dc.contributor.author |
Sigurðsson, Martin Ingi |
dc.contributor.author |
Andersen, Karl Konráð |
dc.contributor.author |
Guðmundsdóttir, Ingibjörg Jóna |
dc.date.accessioned |
2022-10-01T01:03:37Z |
dc.date.available |
2022-10-01T01:03:37Z |
dc.date.issued |
2022-05-31 |
dc.identifier.citation |
Garðarsdóttir , H R , Sigurðsson , M I , Andersen , K K & Guðmundsdóttir , I J 2022 , ' Long-term survival of Icelandic women following acute myocardial infarction ' , Scandinavian Cardiovascular Journal , vol. 56 , no. 1 , pp. 114-120 . https://doi.org/10.1080/14017431.2022.2075561 |
dc.identifier.issn |
1401-7431 |
dc.identifier.other |
60581474 |
dc.identifier.other |
c89e39ba-9919-46d2-8269-a559f1fb5d7c |
dc.identifier.other |
85131179976 |
dc.identifier.other |
35638773 |
dc.identifier.other |
unpaywall: 10.1080/14017431.2022.2075561 |
dc.identifier.uri |
https://hdl.handle.net/20.500.11815/3507 |
dc.description |
Publisher Copyright: © 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. |
dc.description.abstract |
Objective. To evaluate the impact of sex on treatment and survival after acute myocardial infarction (AMI) in Iceland. Methods. A retrospective, nationwide cohort study of patients with STEMI (2008–2018) and NSTEMI (2013–2018) and obstructive coronary artery disease. Patient and procedural information were obtained from a registry and electronic health records. Survival was estimated with Kaplan–Meier method and Cox regression analysis used to identify risk factors for long-term mortality. Excess mortality from the AMI episode was estimated by comparing the survival with age- and sex-matched population in Iceland at 30-day interval. Results. A total of 1345 STEMI-patients (24% women) and 1249 NSTEMI-patients (24% women) were evaluated. Women with STEMI (mean age: 71 ± 11 vs. 67 ± 12) and NSTEMI (mean age: 69 ± 13 vs. 62 ± 12) were older and less likely to have previous cardiovascular disease. There was neither sex difference in the extent of coronary artery disease nor treatment. Although crude one-year post-STEMI survival was lower for women (88.7% vs. 93.4%, p =.006), female sex was not an independent risk factor after adjusting for age and co-morbidities after STEMI and was protective for NSTEMI (HR 0.67, 95% CI: 0.46–0.97). There was excess 30-day mortality in both STEMI and NSTEMI for women compared with sex-, age- and inclusion year-matched Icelandic population, but thereafter the mortality rate was similar. Conclusion. Women and men with AMI in Iceland receive comparable treatment including revascularization and long-term survival appears similar. Prognosis after NSTEMI is better in women, whereas higher early mortality after STEMI may be caused by delays in presentation and diagnosis. |
dc.format.extent |
7 |
dc.format.extent |
1390084 |
dc.format.extent |
114-120 |
dc.language.iso |
en |
dc.relation.ispartofseries |
Scandinavian Cardiovascular Journal; 56(1) |
dc.rights |
info:eu-repo/semantics/openAccess |
dc.subject |
Svæfinga- og gjörgæslulæknisfræði |
dc.subject |
Hjartalæknisfræði |
dc.subject |
Acute myocardial infarction |
dc.subject |
excess mortality |
dc.subject |
long-term survival |
dc.subject |
sex difference |
dc.subject |
ST Elevation Myocardial Infarction/diagnosis |
dc.subject |
Humans |
dc.subject |
Middle Aged |
dc.subject |
Male |
dc.subject |
Non-ST Elevated Myocardial Infarction/diagnosis |
dc.subject |
Coronary Artery Disease |
dc.subject |
Myocardial Infarction/diagnosis |
dc.subject |
Sex Factors |
dc.subject |
Aged, 80 and over |
dc.subject |
Female |
dc.subject |
Aged |
dc.subject |
Iceland/epidemiology |
dc.subject |
Retrospective Studies |
dc.subject |
Cohort Studies |
dc.subject |
Cardiology and Cardiovascular Medicine |
dc.title |
Long-term survival of Icelandic women following acute myocardial infarction |
dc.type |
/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article |
dc.description.version |
Peer reviewed |
dc.identifier.doi |
10.1080/14017431.2022.2075561 |
dc.relation.url |
http://www.scopus.com/inward/record.url?scp=85131179976&partnerID=8YFLogxK |
dc.contributor.department |
Faculty of Medicine |