Opin vísindi

National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio : A pooled analysis of 458 population-based studies in Asian and Western countries

Show simple item record

dc.contributor.author Taddei, Cristina
dc.contributor.author Jackson, Rod
dc.contributor.author Zhou, Bin
dc.contributor.author Bixby, Honor
dc.contributor.author Danaei, Goodarz
dc.contributor.author Di Cesare, Mariachiara
dc.contributor.author Kuulasmaa, Kari
dc.contributor.author Hajifathalian, Kaveh
dc.contributor.author Bentham, James
dc.contributor.author Bennett, James E.
dc.contributor.author Aekplakorn, Wichai
dc.contributor.author Cifkova, Renata
dc.contributor.author Dallongeville, Jean
dc.contributor.author Debacquer, Dirk
dc.contributor.author Giampaoli, Simona
dc.contributor.author Guðnason, Vilmundur G.
dc.contributor.author Khang, Young Ho
dc.contributor.author Laatikainen, Tiina
dc.contributor.author Mann, Jimi
dc.contributor.author Marques-Vidal, Pedro
dc.contributor.author Mensah, Georgea
dc.contributor.author Müller-Nurasyid, Martina
dc.contributor.author Ninomiya, Toshiharu
dc.contributor.author Petkeviciene, Janina
dc.contributor.author Rodríguez-Artalejo, Fernando
dc.contributor.author Servais, Jennifer
dc.contributor.author Söderberg, Stefan
dc.contributor.author Stavreski, Bill
dc.contributor.author Wilsgaard, Tom
dc.contributor.author Zdrojewski, Tomasz
dc.contributor.author Zhao, Dong
dc.contributor.author Stevens, Gretchen A.
dc.contributor.author Savin, Stefan
dc.contributor.author Cowan, Melanie J.
dc.contributor.author Riley, Leanne M.
dc.contributor.author Ezzati, Majid
dc.contributor.author Adams, Robert J.
dc.contributor.author Ahrens, Wolfgang
dc.contributor.author Amouyel, Philippe
dc.contributor.author Amuzu, Antoinette
dc.contributor.author Anderssen, Sigmund A.
dc.contributor.author Ariansen, Inger
dc.contributor.author Arveiler, Dominique
dc.contributor.author Aspelund, Thor
dc.contributor.author Auvinen, Juha
dc.contributor.author Avdicová, Mária
dc.contributor.author Banach, Maciej
dc.contributor.author Bandosz, Piotr
dc.contributor.author Banegas, José R.
dc.contributor.author Barbagallo, Carlo M.
dc.contributor.author Bata, Iqbal
dc.contributor.author Baur, Louise A.
dc.contributor.author Beaglehole, Robert
dc.contributor.author Bernotiene, Gailute
dc.contributor.author Bi, Yufang
dc.contributor.author Bienek, Asako
dc.contributor.author Björkelund, Cecilia
dc.contributor.author Bo, Simona
dc.contributor.author Boehm, Bernhard O.
dc.contributor.author Bonaccio, Marialaura
dc.contributor.author Bongard, Vanina
dc.contributor.author Borchini, Rossana
dc.contributor.author Borghs, Herman
dc.contributor.author Breckenkamp, Juergen
dc.contributor.author Brenner, Hermann
dc.contributor.author Bruno, Graziella
dc.contributor.author Busch, Markusa
dc.contributor.author Cabreradeleón, Antonio
dc.contributor.author Capuano, Vincenzo
dc.contributor.author Casanueva, Felipe F.
dc.contributor.author Casas, Juan Pablo
dc.contributor.author Caserta, Carmelo A.
dc.contributor.author Censi, Laura
dc.contributor.author Chen, Fangfang
dc.contributor.author Chen, Shuohua
dc.contributor.author Chirlaque, María Dolores
dc.contributor.author Cho, Belong
dc.contributor.author Cho, Yumi
dc.contributor.author Chudek, Jerzy
dc.contributor.author Claessens, Frank
dc.contributor.author Clarke, Janine
dc.contributor.author Clays, Els
dc.contributor.author Cooper, Cyrus
dc.contributor.author Costanzo, Simona
dc.contributor.author Cottel, Dominique
dc.contributor.author Cowell, Chris
dc.contributor.author Crujeiras, Ana B.
dc.contributor.author Cui, Liufu
dc.contributor.author D'Arrigo, Graziella
dc.contributor.author Dauchet, Luc
dc.contributor.author De Backer, Guy
dc.contributor.author De Bacquer, Dirk
dc.contributor.author De Gaetano, Giovanni
dc.contributor.author De Henauw, Stefaan
dc.contributor.author De Smedt, Delphine
dc.contributor.author Dennison, Elaine
dc.contributor.author Deschamps, Valérie
dc.contributor.author Dicastelnuovo, Augusto
dc.contributor.author Dobson, Annette J.
dc.contributor.author Donfrancesco, Chiara
dc.contributor.author Döring, Angela
dc.contributor.author Drygas, Wojciech
dc.contributor.author Du, Yong
dc.contributor.author Dziankowska-Zaborszczyk, Elzbieta
dc.contributor.author Eggertsen, Robert
dc.contributor.author Ekelund, Ulf
dc.contributor.author Elosua, Roberto
dc.contributor.author Eriksson, Johan G.
dc.contributor.author Evans, Alun
dc.contributor.author Faeh, David
dc.contributor.author Felix-Redondo, Francisco J.
dc.contributor.author Fernández-Bergés, Daniel
dc.contributor.author Ferrari, Marika
dc.contributor.author Ferrieres, Jean
dc.contributor.author Finn, Joseph D.
dc.contributor.author Forslund, Ann Sofie
dc.contributor.author Forsner, Maria
dc.contributor.author Frontera, Guillermo
dc.contributor.author Fujita, Yuki
dc.contributor.author Gaciong, Zbigniew
dc.contributor.author Galvano, Fabio
dc.contributor.author Gao, Jingli
dc.contributor.author Garcia-De-La-Hera, Manoli
dc.contributor.author Garnett, Sarahp
dc.contributor.author Gaspoz, Jean Michel
dc.contributor.author Gasull, Magda
dc.contributor.author Gates, Louise
dc.contributor.author Gianfagna, Francesco
dc.contributor.author Gill, Tiffany K.
dc.contributor.author Giovannelli, Jonathan
dc.contributor.author Goltzman, David
dc.contributor.author Gonzalezgross, Marcela
dc.contributor.author Gottrand, Frederic
dc.contributor.author Graff-Iversen, Sidsel
dc.contributor.author Grafnetter, Dušan
dc.contributor.author Gregor, Ronald D.
dc.contributor.author Grodzicki, Tomasz
dc.contributor.author Grosso, Giuseppe
dc.contributor.author Gruden, Grabriella
dc.contributor.author Gu, Dongfeng
dc.contributor.author Guallar-Castillón, Pilar
dc.contributor.author Gudmundsson, Elias F.
dc.contributor.author Guessous, Idris
dc.contributor.author Gunnlaugsdottir, Johanna
dc.contributor.author Gutzwiller, Felix
dc.contributor.author Hardy, Rebecca
dc.contributor.author Hata, Jun
dc.contributor.author Haugsgjerd, Teresa
dc.contributor.author Hayes, Alison J.
dc.contributor.author He, Jiang
dc.contributor.author He, Yuna
dc.contributor.author Herrala, Sauli
dc.contributor.author Tapanihihtaniemi, Ilpo
dc.contributor.author Hobbs, Michael
dc.contributor.author Hopman, Wilma M.
dc.contributor.author Maríahuerta, José
dc.contributor.author Huybrechts, Inge
dc.contributor.author Iacoviello, Licia
dc.contributor.author Iannone, Anna G.
dc.contributor.author Ikeda, Nayu
dc.contributor.author Iwasaki, Masanori
dc.contributor.author Jamrozik, Konrad
dc.contributor.author Janszky, Imre
dc.contributor.author Jarvelin, Marjo Riitta
dc.contributor.author Jasienska, Grazyna
dc.contributor.author Jennings, Garry
dc.contributor.author Jeong, Seung Lyeal
dc.contributor.author Qiangjiang, Chao
dc.contributor.author Joffres, Michel
dc.contributor.author Jokelainen, Jari J.
dc.contributor.author Jonas, Jost B.
dc.contributor.author Jóźwiak, Jacek
dc.contributor.author Kajantie, Eero O.
dc.contributor.author Kauhanen, Jussi
dc.contributor.author Keil, Ulrich
dc.contributor.author Keinänen-Kiukaanniemi, Sirkka
dc.contributor.author Kersting, Mathilde
dc.contributor.author Kiechl-Kohlendorfer, Ursula
dc.contributor.author Kiechl, Stefan
dc.contributor.author Kim, Jeongseon
dc.contributor.author Kim, Yeon Yong
dc.contributor.author Klumbiene, Jurate
dc.contributor.author Knoflach, Michael
dc.contributor.author Ko, Stephanie
dc.contributor.author Kolle, Elin
dc.contributor.author Korpelainen, Raija
dc.contributor.author Koskinen, Seppo
dc.contributor.author Kouda, Katsuyasu
dc.contributor.author Kratzer, Wolfgang
dc.contributor.author Kriemler, Susi
dc.contributor.author Krokstad, Steinar
dc.contributor.author Kujala, Urhom
dc.contributor.author Kurjata, Pawel
dc.contributor.author Hinglam, Tai
dc.contributor.author Lanska, Vera
dc.contributor.author Lappas, Georg
dc.contributor.author Laugsand, Lars E.
dc.contributor.author Lee, Jeonghee
dc.contributor.author Lehtimäki, Terho
dc.contributor.author Li, Yanping
dc.contributor.author Lilly, Christa L.
dc.contributor.author Lin, Xu
dc.contributor.author Lind, Lars
dc.contributor.author Lissner, Lauren
dc.contributor.author Liu, Jing
dc.contributor.author Lopez-Garcia, Esther
dc.contributor.author Lorbeer, Roberto
dc.contributor.author Eugeniolozano, José
dc.contributor.author Luksiene, Dalia
dc.contributor.author Lundqvist, Annamari
dc.contributor.author Lundqvist, Robert
dc.contributor.author Lytsy, Per
dc.contributor.author Ma, Guansheng
dc.contributor.author Machi, Suka
dc.contributor.author Maggi, Stefania
dc.contributor.author Magliano, Dianna J.
dc.contributor.author Mann, Jim I.
dc.contributor.author Manzato, Enzo
dc.contributor.author Mathiesen, Ellisiv B.
dc.contributor.author McLachlan, Stela
dc.contributor.author McLean, Rachael M.
dc.contributor.author Scott, B. S.
dc.contributor.author Meirhaeghe, Aline
dc.contributor.author Christa, C.
dc.contributor.author Metcalf, Patricia
dc.contributor.author Mi, Jie
dc.contributor.author Miller, Jody C.
dc.contributor.author Moreno, Luisa
dc.contributor.author Morin, Suzanne
dc.contributor.author Mossakowska, Malgorzata
dc.contributor.author Muiesan, Maria L.
dc.contributor.author Mursu, Jaakko
dc.contributor.author Nakamura, Harunobu
dc.contributor.author Námešná, Jana
dc.contributor.author Matthias, M.
dc.contributor.author Marianavarrete-Muñoz, Eva
dc.contributor.author Neal, William A.
dc.contributor.author Nenko, Ilona
dc.contributor.author Niiranen, Teemu J.
dc.contributor.author Ning, Guang
dc.contributor.author Noale, Marianna
dc.contributor.author Norie, Sawada
dc.contributor.author Noto, Davide
dc.contributor.author O'Neill, Terence
dc.contributor.author O'Reilly, Dermot
dc.contributor.author Oh, Kyungwon
dc.contributor.author Olafsson, Örn
dc.contributor.author Michelpaccaud, Fred
dc.contributor.author Pajak, Andrzej
dc.contributor.author Palmieri, Luigi
dc.contributor.author Panza, Francesco
dc.contributor.author Parnell, Winsome R.
dc.contributor.author Peltonen, Markku
dc.contributor.author Peters, Annette
dc.contributor.author Petersmann, Astrid
dc.contributor.author Pigeot, Iris
dc.contributor.author Pilotto, Lorenza
dc.contributor.author Piwonska, Aleksandra
dc.contributor.author Plans-Rubió, Pedro
dc.contributor.author Porta, Miquel
dc.contributor.author Price, Jacqueline F.
dc.contributor.author Puder, Jardena J.
dc.contributor.author Puhakka, Soilee
dc.contributor.author Radisauskas, Ricardas
dc.contributor.author Raitakari, Olli
dc.contributor.author Ramos, Rafel
dc.contributor.author Redon, Josep
dc.contributor.author Rigo, Fernando
dc.contributor.author Rodriguez-Perez, Maríadel Cristo
dc.contributor.author Romaguera, Dora
dc.contributor.author Ronkainen, Kimmo
dc.contributor.author Rosengren, Annika
dc.contributor.author Roy, Joel G.R.
dc.contributor.author Ruidavets, Jean Bernard
dc.contributor.author Rutkowski, Marcin
dc.contributor.author Salanave, Benoit
dc.contributor.author Salmerón, Diego
dc.contributor.author Salomaa, Veikko
dc.contributor.author Salonen, Jukka T.
dc.contributor.author Salvetti, Massimo
dc.contributor.author Sans, Susana
dc.contributor.author Saramies, Jouko L.
dc.contributor.author Saum, Kai Uwe
dc.contributor.author Scheidt-Nave, Christa
dc.contributor.author Schienkiewitz, Anja
dc.contributor.author Schipf, Sabine
dc.contributor.author Schmidt, Carsteno
dc.contributor.author Schöttker, Ben
dc.contributor.author Sebert, Sylvain
dc.contributor.author Sen, Abhijit
dc.contributor.author Shaw, Jonathan E.
dc.contributor.author Shibuya, Kenji
dc.contributor.author Wookshin, Dong
dc.contributor.author Shiri, Rahman
dc.contributor.author Simons, Judith
dc.contributor.author Simons, Leon A.
dc.contributor.author Sjöström, Michael
dc.contributor.author Slowikowska-Hilczer, Jolanta
dc.contributor.author Slusarczyk, Przemyslaw
dc.contributor.author Solfrizzi, Vincenzo
dc.contributor.author Sonestedt, Emily
dc.contributor.author Soumare, Aicha
dc.contributor.author Staessen, Jan A.
dc.contributor.author Stathopoulou, Maria G.
dc.contributor.author Steene-Johannessen, Jostein
dc.contributor.author Stehle, Peter
dc.contributor.author Stieber, Jutta
dc.contributor.author Stöckl, Doris
dc.contributor.author Stokwiszewski, Jakub
dc.contributor.author Sundström, Johan
dc.contributor.author Suriyawongpaisal, Paibul
dc.contributor.author Tamosiunas, Abdonas
dc.contributor.author Jootan, Eng
dc.contributor.author Taylor, Anne
dc.contributor.author Tell, Grethe
dc.contributor.author Thijs, Lutgarde
dc.contributor.author Tolonen, Hanna K.
dc.contributor.author Topór-Madry, Roman
dc.contributor.author Josétormo, María
dc.contributor.author Torrent, Maties
dc.contributor.author Tsugane, Shoichiro
dc.contributor.author Tuomainen, Tomi Pekka
dc.contributor.author Tuomilehto, Jaakko
dc.contributor.author Tzourio, Christophe
dc.contributor.author Uusitalo, Hannu M.T.
dc.contributor.author Vanherck, Koen
dc.contributor.author Vanderschueren, Dirk
dc.contributor.author Vanuzzo, Diego
dc.contributor.author Vatten, Lars
dc.contributor.author Vega, Tomas
dc.contributor.author Veronesi, Giovanni
dc.contributor.author Vioque, Jesus
dc.contributor.author Virtanen, Jyrkik
dc.contributor.author Visvikis-Siest, Sophie
dc.contributor.author Vollenweider, Peter
dc.contributor.author Voutilainen, Sari
dc.contributor.author Vrijheid, Martine
dc.contributor.author Wagner, Aline
dc.contributor.author Wagner, Anne
dc.contributor.author Wang, Ming Dong
dc.contributor.author Wang, Qian
dc.contributor.author Xingwang, Ya
dc.contributor.author Wannamethee, S. Goya
dc.contributor.author Wei, Wenbin
dc.contributor.author Wiecek, Andrzej
dc.contributor.author Willeit, Johann
dc.contributor.author Willeit, Peter
dc.contributor.author Wojtyniak, Bogdan
dc.contributor.author Wong, Andrew
dc.contributor.author Woodward, Mark
dc.contributor.author Giwercmanwu, Aleksander
dc.contributor.author Wu, Frederick C.
dc.contributor.author Wu, Shouling
dc.contributor.author Xu, Haiquan
dc.contributor.author Xu, Liang
dc.contributor.author Yan, Weili
dc.contributor.author Yang, Xiaoguang
dc.contributor.author Ye, Xingwang
dc.contributor.author Yoshihara, Akihiro
dc.contributor.author Zambon, Sabina
dc.contributor.author Zhao, Wenhua
dc.date.accessioned 2022-07-28T01:03:09Z
dc.date.available 2022-07-28T01:03:09Z
dc.date.issued 2020-02-01
dc.identifier.citation Taddei , C , Jackson , R , Zhou , B , Bixby , H , Danaei , G , Di Cesare , M , Kuulasmaa , K , Hajifathalian , K , Bentham , J , Bennett , J E , Aekplakorn , W , Cifkova , R , Dallongeville , J , Debacquer , D , Giampaoli , S , Guðnason , V G , Khang , Y H , Laatikainen , T , Mann , J , Marques-Vidal , P , Mensah , G , Müller-Nurasyid , M , Ninomiya , T , Petkeviciene , J , Rodríguez-Artalejo , F , Servais , J , Söderberg , S , Stavreski , B , Wilsgaard , T , Zdrojewski , T , Zhao , D , Stevens , G A , Savin , S , Cowan , M J , Riley , L M , Ezzati , M , Adams , R J , Ahrens , W , Amouyel , P , Amuzu , A , Anderssen , S A , Ariansen , I , Arveiler , D , Aspelund , T , Auvinen , J , Avdicová , M , Banach , M , Bandosz , P , Banegas , J R , Barbagallo , C M , Bata , I , Baur , L A , Beaglehole , R , Bernotiene , G , Bi , Y , Bienek , A , Björkelund , C , Bo , S , Boehm , B O , Bonaccio , M , Bongard , V , Borchini , R , Borghs , H , Breckenkamp , J , Brenner , H , Bruno , G , Busch , M , Cabreradeleón , A , Capuano , V , Casanueva , F F , Casas , J P , Caserta , C A , Censi , L , Chen , F , Chen , S , Chirlaque , M D , Cho , B , Cho , Y , Chudek , J , Claessens , F , Clarke , J , Clays , E , Cooper , C , Costanzo , S , Cottel , D , Cowell , C , Crujeiras , A B , Cui , L , D'Arrigo , G , Dauchet , L , De Backer , G , De Bacquer , D , De Gaetano , G , De Henauw , S , De Smedt , D , Dennison , E , Deschamps , V , Dicastelnuovo , A , Dobson , A J , Donfrancesco , C , Döring , A , Drygas , W , Du , Y , Dziankowska-Zaborszczyk , E , Eggertsen , R , Ekelund , U , Elosua , R , Eriksson , J G , Evans , A , Faeh , D , Felix-Redondo , F J , Fernández-Bergés , D , Ferrari , M , Ferrieres , J , Finn , J D , Forslund , A S , Forsner , M , Frontera , G , Fujita , Y , Gaciong , Z , Galvano , F , Gao , J , Garcia-De-La-Hera , M , Garnett , S , Gaspoz , J M , Gasull , M , Gates , L , Gianfagna , F , Gill , T K , Giovannelli , J , Goltzman , D , Gonzalezgross , M , Gottrand , F , Graff-Iversen , S , Grafnetter , D , Gregor , R D , Grodzicki , T , Grosso , G , Gruden , G , Gu , D , Guallar-Castillón , P , Gudmundsson , E F , Guessous , I , Gunnlaugsdottir , J , Gutzwiller , F , Hardy , R , Hata , J , Haugsgjerd , T , Hayes , A J , He , J , He , Y , Herrala , S , Tapanihihtaniemi , I , Hobbs , M , Hopman , W M , Maríahuerta , J , Huybrechts , I , Iacoviello , L , Iannone , A G , Ikeda , N , Iwasaki , M , Jamrozik , K , Janszky , I , Jarvelin , M R , Jasienska , G , Jennings , G , Jeong , S L , Qiangjiang , C , Joffres , M , Jokelainen , J J , Jonas , J B , Jóźwiak , J , Kajantie , E O , Kauhanen , J , Keil , U , Keinänen-Kiukaanniemi , S , Kersting , M , Kiechl-Kohlendorfer , U , Kiechl , S , Kim , J , Kim , Y Y , Klumbiene , J , Knoflach , M , Ko , S , Kolle , E , Korpelainen , R , Koskinen , S , Kouda , K , Kratzer , W , Kriemler , S , Krokstad , S , Kujala , U , Kurjata , P , Hinglam , T , Lanska , V , Lappas , G , Laugsand , L E , Lee , J , Lehtimäki , T , Li , Y , Lilly , C L , Lin , X , Lind , L , Lissner , L , Liu , J , Lopez-Garcia , E , Lorbeer , R , Eugeniolozano , J , Luksiene , D , Lundqvist , A , Lundqvist , R , Lytsy , P , Ma , G , Machi , S , Maggi , S , Magliano , D J , Mann , J I , Manzato , E , Mathiesen , E B , McLachlan , S , McLean , R M , Scott , B S , Meirhaeghe , A , Christa , C , Metcalf , P , Mi , J , Miller , J C , Moreno , L , Morin , S , Mossakowska , M , Muiesan , M L , Mursu , J , Nakamura , H , Námešná , J , Matthias , M , Marianavarrete-Muñoz , E , Neal , W A , Nenko , I , Niiranen , T J , Ning , G , Noale , M , Norie , S , Noto , D , O'Neill , T , O'Reilly , D , Oh , K , Olafsson , Ö , Michelpaccaud , F , Pajak , A , Palmieri , L , Panza , F , Parnell , W R , Peltonen , M , Peters , A , Petersmann , A , Pigeot , I , Pilotto , L , Piwonska , A , Plans-Rubió , P , Porta , M , Price , J F , Puder , J J , Puhakka , S , Radisauskas , R , Raitakari , O , Ramos , R , Redon , J , Rigo , F , Rodriguez-Perez , M C , Romaguera , D , Ronkainen , K , Rosengren , A , Roy , J G R , Ruidavets , J B , Rutkowski , M , Salanave , B , Salmerón , D , Salomaa , V , Salonen , J T , Salvetti , M , Sans , S , Saramies , J L , Saum , K U , Scheidt-Nave , C , Schienkiewitz , A , Schipf , S , Schmidt , C , Schöttker , B , Sebert , S , Sen , A , Shaw , J E , Shibuya , K , Wookshin , D , Shiri , R , Simons , J , Simons , L A , Sjöström , M , Slowikowska-Hilczer , J , Slusarczyk , P , Solfrizzi , V , Sonestedt , E , Soumare , A , Staessen , J A , Stathopoulou , M G , Steene-Johannessen , J , Stehle , P , Stieber , J , Stöckl , D , Stokwiszewski , J , Sundström , J , Suriyawongpaisal , P , Tamosiunas , A , Jootan , E , Taylor , A , Tell , G , Thijs , L , Tolonen , H K , Topór-Madry , R , Josétormo , M , Torrent , M , Tsugane , S , Tuomainen , T P , Tuomilehto , J , Tzourio , C , Uusitalo , H M T , Vanherck , K , Vanderschueren , D , Vanuzzo , D , Vatten , L , Vega , T , Veronesi , G , Vioque , J , Virtanen , J , Visvikis-Siest , S , Vollenweider , P , Voutilainen , S , Vrijheid , M , Wagner , A , Wagner , A , Wang , M D , Wang , Q , Xingwang , Y , Wannamethee , S G , Wei , W , Wiecek , A , Willeit , J , Willeit , P , Wojtyniak , B , Wong , A , Woodward , M , Giwercmanwu , A , Wu , F C , Wu , S , Xu , H , Xu , L , Yan , W , Yang , X , Ye , X , Yoshihara , A , Zambon , S & Zhao , W 2020 , ' National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio : A pooled analysis of 458 population-based studies in Asian and Western countries ' , International Journal of Epidemiology , vol. 49 , no. 1 , pp. 173-192 . https://doi.org/10.1093/ije/dyz099
dc.identifier.issn 0300-5771
dc.identifier.other PURE: 38450912
dc.identifier.other PURE UUID: f461d68d-f21e-4665-bed7-01fae0b35cbd
dc.identifier.other Scopus: 85074478745
dc.identifier.uri https://hdl.handle.net/20.500.11815/3303
dc.description This work was supported by the Wellcome Trust (grant numbers 101506/Z/13/Z and Research Training Fellowship 203616/Z/16/Z). R.C. acknowledges funding from the Ministry of Health of the Czech Republic (grant number 15-27109A). Publisher Copyright: © 2019 The Author(s) 2019. Published by Oxford University Press on behalf of the International Epidemiological Association.
dc.description.abstract Background: Although high-density lipoprotein (HDL) and non-HDL cholesterol have opposite associations with coronary heart disease, multi-country reports of lipid trends only use total cholesterol (TC). Our aim was to compare trends in total, HDL and non-HDL cholesterol and the total-to-HDL cholesterol ratio in Asian and Western countries. Methods: We pooled 458 population-based studies with 82.1 million participants in 23 Asian and Western countries. We estimated changes in mean total, HDL and non-HDL cholesterol and mean total-to-HDL cholesterol ratio by country, sex and age group. Results: Since ∼1980, mean TC increased in Asian countries. In Japan and South Korea, the TC rise was due to rising HDL cholesterol, which increased by up to 0.17 mmol/L per decade in Japanese women; in China, it was due to rising non-HDL cholesterol. TC declined in Western countries, except in Polish men. The decline was largest in Finland and Norway, at ∼0.4 mmol/L per decade. The decline in TC in most Western countries was the net effect of an increase in HDL cholesterol and a decline in non-HDL cholesterol, with the HDL cholesterol increase largest in New Zealand and Switzerland. Mean total-to-HDL cholesterol ratio declined in Japan, South Korea and most Western countries, by as much as ∼0.7 per decade in Swiss men (equivalent to ∼26% decline in coronary heart disease risk per decade). The ratio increased in China. Conclusions: HDL cholesterol has risen and the total-to-HDL cholesterol ratio has declined in many Western countries, Japan and South Korea, with only a weak correlation with changes in TC or non-HDL cholesterol.
dc.format.extent 20
dc.format.extent 173-192
dc.language.iso en
dc.relation.ispartofseries International Journal of Epidemiology; 49(1)
dc.rights info:eu-repo/semantics/openAccess
dc.subject Blóðfita
dc.subject Kólesteról
dc.subject Blood lipids
dc.subject HDL cholesterol
dc.subject LDL cholesterol
dc.subject Multi-country study
dc.subject Total cholesterol
dc.subject Epidemiology
dc.title National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio : A pooled analysis of 458 population-based studies in Asian and Western countries
dc.type /dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article
dc.description.version Peer reviewed
dc.identifier.pmid 31321439
dc.identifier.doi https://doi.org/10.1093/ije/dyz099
dc.relation.url http://www.scopus.com/inward/record.url?scp=85074478745&partnerID=8YFLogxK
dc.contributor.department Faculty of Medicine


Files in this item

This item appears in the following Collection(s)

Show simple item record