dc.contributor |
Landspitali - The National University Hospital of Iceland |
dc.contributor.author |
Chew, Michelle S. |
dc.contributor.author |
Kattainen, Salla |
dc.contributor.author |
Haase, Nicolai |
dc.contributor.author |
Buanes, Eirik A. |
dc.contributor.author |
Kristinsdóttir, Linda B. |
dc.contributor.author |
Hofsø, Kristin |
dc.contributor.author |
Laake, Jon Henrik |
dc.contributor.author |
Kvåle, Reidar |
dc.contributor.author |
Hästbacka, Johanna |
dc.contributor.author |
Reinikainen, Matti |
dc.contributor.author |
Bendel, Stepani |
dc.contributor.author |
Varpula, Tero |
dc.contributor.author |
Walther, Sten |
dc.contributor.author |
Perner, Anders |
dc.contributor.author |
Flaatten, Hans K. |
dc.contributor.author |
Sigurðsson, Martin Ingi |
dc.date.accessioned |
2022-01-26T01:02:19Z |
dc.date.available |
2022-01-26T01:02:19Z |
dc.date.issued |
2022-01 |
dc.identifier.citation |
Chew , M S , Kattainen , S , Haase , N , Buanes , E A , Kristinsdóttir , L B , Hofsø , K , Laake , J H , Kvåle , R , Hästbacka , J , Reinikainen , M , Bendel , S , Varpula , T , Walther , S , Perner , A , Flaatten , H K & Sigurðsson , M I 2022 , ' A descriptive study of the surge response and outcomes of ICU patients with COVID-19 during first wave in Nordic countries ' , Acta Anaesthesiologica Scandinavica , vol. 66 , no. 1 , pp. 56-64 . https://doi.org/10.1111/aas.13983 |
dc.identifier.issn |
0001-5172 |
dc.identifier.other |
42214175 |
dc.identifier.other |
5f1fa951-6405-4cd2-a0c0-4226404ff6a1 |
dc.identifier.other |
85116132838 |
dc.identifier.other |
34570897 |
dc.identifier.other |
000702990200001 |
dc.identifier.uri |
https://hdl.handle.net/20.500.11815/2858 |
dc.description |
Funding: NordForsk (Nordic COVID-19 Activities), Finnish Society of Intensive Care. Publisher Copyright: © 2021 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd |
dc.description.abstract |
Background: We sought to provide a description of surge response strategies and characteristics, clinical management and outcomes of patients with severe COVID-19 in the intensive care unit (ICU) during the first wave of the pandemic in Denmark, Finland, Iceland, Norway and Sweden. Methods: Representatives from the national ICU registries for each of the five countries provided clinical data and a description of the strategies to allocate ICU resources and increase the ICU capacity during the pandemic. All adult patients admitted to the ICU for COVID-19 disease during the first wave of COVID-19 were included. The clinical characteristics, ICU management and outcomes of individual countries were described with descriptive statistics. Results: Most countries more than doubled their ICU capacity during the pandemic. For patients positive for SARS-CoV-2, the ratio of requiring ICU admission for COVID-19 varied substantially (1.6%–6.7%). Apart from age (proportion of patients aged 65 years or over between 29% and 62%), baseline characteristics, chronic comorbidity burden and acute presentations of COVID-19 disease were similar among the five countries. While utilization of invasive mechanical ventilation was high (59%–85%) in all countries, the proportion of patients receiving renal replacement therapy (7%–26%) and various experimental therapies for COVID-19 disease varied substantially (e.g. use of hydroxychloroquine 0%–85%). Crude ICU mortality ranged from 11% to 33%. Conclusion: There was substantial variability in the critical care response in Nordic ICUs to the first wave of COVID-19 pandemic, including usage of experimental medications. While ICU mortality was low in all countries, the observed variability warrants further attention. |
dc.format.extent |
9 |
dc.format.extent |
496129 |
dc.format.extent |
56-64 |
dc.language.iso |
en |
dc.relation.ispartofseries |
Acta Anaesthesiologica Scandinavica; 66(1) |
dc.rights |
info:eu-repo/semantics/openAccess |
dc.subject |
COVID-19 |
dc.subject |
Dánartíðni |
dc.subject |
Norðurlönd |
dc.subject |
Norðurlönd |
dc.subject |
Svæfinga- og gjörgæslulæknisfræði |
dc.subject |
COVID-19 |
dc.subject |
mortality |
dc.subject |
Nordic |
dc.subject |
SARS-CoV2 |
dc.subject |
Intensive Care Units |
dc.subject |
SARS-CoV-2 |
dc.subject |
Pandemics |
dc.subject |
Humans |
dc.subject |
Adult |
dc.subject |
Critical Care |
dc.subject |
Aged |
dc.subject |
Anesthesiology and Pain Medicine |
dc.title |
A descriptive study of the surge response and outcomes of ICU patients with COVID-19 during first wave in Nordic countries |
dc.type |
/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article |
dc.description.version |
Peer reviewed |
dc.identifier.doi |
10.1111/aas.13983 |
dc.relation.url |
http://www.scopus.com/inward/record.url?scp=85116132838&partnerID=8YFLogxK |
dc.contributor.department |
Perioperative Services |
dc.contributor.department |
Faculty of Medicine |