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A descriptive study of the surge response and outcomes of ICU patients with COVID-19 during first wave in Nordic countries

A descriptive study of the surge response and outcomes of ICU patients with COVID-19 during first wave in Nordic countries


Titill: A descriptive study of the surge response and outcomes of ICU patients with COVID-19 during first wave in Nordic countries
Höfundur: Chew, Michelle S.
Kattainen, Salla
Haase, Nicolai
Buanes, Eirik A.
Kristinsdóttir, Linda B.
Hofsø, Kristin
Laake, Jon Henrik
Kvåle, Reidar
Hästbacka, Johanna
Reinikainen, Matti
... 6 fleiri höfundar Sýna alla höfunda
Útgáfa: 2022-01
Tungumál: Enska
Umfang: 9
Háskóli/Stofnun: Landspitali - The National University Hospital of Iceland
Deild: Perioperative Services
Faculty of Medicine
Birtist í: Acta Anaesthesiologica Scandinavica; 66(1)
ISSN: 0001-5172
DOI: 10.1111/aas.13983
Efnisorð: COVID-19; Dánartíðni; Norðurlönd; Norðurlönd; Svæfinga- og gjörgæslulæknisfræði; COVID-19; mortality; Nordic; SARS-CoV2; Intensive Care Units; SARS-CoV-2; Pandemics; Humans; Adult; Critical Care; Aged; Anesthesiology and Pain Medicine; SDG 3 - Good Health and Well-being
URI: https://hdl.handle.net/20.500.11815/2858

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Tilvitnun:

Chew, M S, Kattainen, S, Haase, N, Buanes, E A, Kristinsdóttir, L B, Hofsø, K, Laake, J H, Kvåle, R, Hästbacka, J, Reinikainen, M, Bendel, S, Varpula, T, Walther, S, Perner, A, Flaatten, H K & Sigurðsson, M I 2022, 'A descriptive study of the surge response and outcomes of ICU patients with COVID-19 during first wave in Nordic countries', Acta Anaesthesiologica Scandinavica, vol. 66, no. 1, pp. 56-64. https://doi.org/10.1111/aas.13983

Útdráttur:

Background: We sought to provide a description of surge response strategies and characteristics, clinical management and outcomes of patients with severe COVID-19 in the intensive care unit (ICU) during the first wave of the pandemic in Denmark, Finland, Iceland, Norway and Sweden. Methods: Representatives from the national ICU registries for each of the five countries provided clinical data and a description of the strategies to allocate ICU resources and increase the ICU capacity during the pandemic. All adult patients admitted to the ICU for COVID-19 disease during the first wave of COVID-19 were included. The clinical characteristics, ICU management and outcomes of individual countries were described with descriptive statistics. Results: Most countries more than doubled their ICU capacity during the pandemic. For patients positive for SARS-CoV-2, the ratio of requiring ICU admission for COVID-19 varied substantially (1.6%–6.7%). Apart from age (proportion of patients aged 65 years or over between 29% and 62%), baseline characteristics, chronic comorbidity burden and acute presentations of COVID-19 disease were similar among the five countries. While utilization of invasive mechanical ventilation was high (59%–85%) in all countries, the proportion of patients receiving renal replacement therapy (7%–26%) and various experimental therapies for COVID-19 disease varied substantially (e.g. use of hydroxychloroquine 0%–85%). Crude ICU mortality ranged from 11% to 33%. Conclusion: There was substantial variability in the critical care response in Nordic ICUs to the first wave of COVID-19 pandemic, including usage of experimental medications. While ICU mortality was low in all countries, the observed variability warrants further attention.

Athugasemdir:

Funding: NordForsk (Nordic COVID-19 Activities), Finnish Society of Intensive Care. Publisher Copyright: © 2021 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd

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